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Enio R Vasques Estela RR Figueira Joel A Rocha-Filho Cinthia Lanchotte Jorge LS Ximenes Helena B Nader Ivarne LS Tersariol Marcelo A Lima Tiago Rodrigues José EM Cunha Eleazar Chaib Luiz AC D'Albuquerque Flávio HF Galv?o 《Hepatobiliary & pancreatic diseases international : HBPD INT》2022,21(2):190-192
<正>To the Editor:Ischemia-reperfusion injury following surgery and transplantation can lead to irreversible multiorgan failure.Intracellular calcium overload is associated to cellular death during ischemiareperfusion.A recently discovered heparin fragment (HF),trisulfated disaccharide (TD),that acts on sodium-calcium exchanger(NCX) decreasing intracellular Ca2+,showed effectiveness on protecting hepatocytes from ischemia-reperfusion injury [1], 相似文献
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Shruti Chaturvedi Desiree Carcioppolo Li Zhang Keith R. McCrae 《American journal of hematology》2013,88(7):560-565
The advent of plasma exchange has led to a dramatic improvement in the survival of patients with thrombotic thrombocytopenic purpura (TTP), though approximately 10% of patients still die and a third suffer relapses. Clinical features that identify poor risk patients have not been clearly identified. We reviewed 100 patients who were treated for a first episode of TTP at the Cleveland Clinic between 2000 and 2012 to identify factors predictive of poor outcomes. On multivariate analysis, increasing age, especially age > 60 (RR: 7.08, 95% CI: 2.15–23.39, P = 0.002), severe neurological symptoms at presentation (RR: 18.37, 95% CI: I4.19–80.13, P < 0.001) and a persistently elevated LDH level after two plasma exchanges were predictive of mortality. Patients with ADAMTS13 activity above or below 5% did not differ in terms of clinical presentation or mortality and relapse rates, although ADAMTS13 activity > 5% was an independent predictor of adverse renal outcomes (need for dialysis and progression to chronic kidney disease). These variables may be useful for risk stratification and identification of patients who could potentially benefit from early institution of adjunctive therapy. Am. J. Hematol. 88:560–565, 2013. © 2013 Wiley Periodicals, Inc. 相似文献
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Abhishek Chaturvedi Randy Lau Gregory Kicska Gautham P. Reddy 《The international journal of cardiovascular imaging》2013,29(1):3-4
Congenital or acquired communication between left ventricle and right atrium is rare and can be easily overlooked as an eccentric tricuspid regurgitation jet. MRI is the ideal modality for accurate diagnosis, providing details for surgical planning about the location and size of the defect. 相似文献
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Neeraj Parakh Niraj Yadav Sanjeev Kathuria Vivek Chaturvedi Vijay Trehan Sanjay Tyagi 《Indian heart journal》2013,65(1):100-103
The fibrous body between the mitral and aortic valve, known as mitral-aortic intervalvular fibrosa (MAIVF) is prone to infection and injury resulting in pseudo-aneurysm formation. Because of its relative rarity, we are far from making any conclusion regarding the natural history and appropriate therapeutic strategy for this condition. We report two cases of this condition with two different and rare etiologies with strikingly different natural courses, providing insight into the natural course and timing of surgery in this rare entity. 相似文献
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Prospective study of the pattern of lymphatic metastasis in relation to the submandibular gland in patients with carcinoma of the oral cavity 下载免费PDF全文
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This report documents an unusualfinding of scattered psammomatous-type calcification in a well-differentiated adenocarcinoma of the rectosigmoid colon in a 54-year-old woman. The clinical relevance of this histologic feature is discussed, in light of review of the literature. 相似文献