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Objective:To investigate the association between malocclusion/dentofacial anomalies and traumatic dental injuries (TDI) in adolescents.Materials and Methods:The sample of this cross-sectional study comprised 509 adolescents aged 11 to 14 years enrolled at public schools in the city of Osório, southern Brazil. Parents answered a structured questionnaire addressing demographic and socioeconomic characteristics. An examiner who had undergone a training and calibration exercise recorded malocclusion/dentofacial anomalies (Dental Aesthetic Index, DAI), TDI (Andreasen), and dental caries (World Health Organisation). Statistical analyses (SPSS software) involved Poisson regression with robust variance.Results:The prevalence of TDI was 11.6%, and the prevalence of defined, severe, and handicapping malocclusion was 24.0%, 21.6%, and 22.0%, respectively. The multivariate analysis demonstrated that the probability of TDI was approximately twofold higher among adolescents with severe malocclusion (prevalence ratio [PR] 2.22; 95% confidence interval [CI] 1.14–4.31) and handicapping malocclusion (PR 1.95; 95% CI 1.01–3.85) in comparison to those with normal occlusion or minor malocclusion. Defined malocclusion was not significantly associated with the outcome. Among the dentofacial anomalies evaluated, the probability of TDI was nearly twofold higher among adolescents with overjet greater than 3 mm (PR 1.96; 95% CI 1.14–3.37) and 2.2-fold higher among those with an abnormal molar relationship (PR 2.24; 95% CI 1.17–4.32), after controlling for confounding variables.Conclusions:Severe and handicapping malocclusion, accentuated overjet, and abnormal molar relationship were strongly associated with the occurrence of TDI. Future studies should investigate whether the treatment of these conditions can help reduce the occurrence of TDI in adolescents.  相似文献   
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Introduction and hypothesis  

The objective of this study is to evaluate pregnancy’s action on glycosaminoglycans (GAGs) profile in bladder and urethra of female adult rats.  相似文献   
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The aim of this study was to evaluate the influence of endodontic irrigants on adhesion to pulp chamber dentin. Seventy crowns of bovine incisors were cut to expose the pulp chamber. Specimens were divided into seven groups, according to the irrigant solution used: G1, 0.9% sodium chlorite (control); G2, 5.25% NaOCl; G3, 5.25% NaOCl + 17% EDTA; G4, 2% chlorhexidine solution; G5, 2% CHX solution + 17% EDTA; G6, 2% chlorhexidine in a gel base; and G7, 2% CHX gel + 17% EDTA. After irrigation, Clearfil SE Bond was applied to pulp chamber dentin, followed by Filtek Z250 composite. Six rectangular sticks were obtained from each specimen and dentin/resin interface was tested in tension. Bond strength means were analyzed by ANOVA and Tukey test. There was a significant decrease in bond strength associated to NaOCl, whereas chlorhexidine irrigation showed no effects on adhesion. It was concluded that endodontic irrigants affected differently bond strength to pulp chamber dentin.  相似文献   
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This study quantified alterations in root dentin permeability after exposure to different acid beverages. Twenty-five third molars were sectioned below the cementoenamel junction, the root segment was collected, and the pulp tissue was removed. The root segments were connected to a hydraulic pressure apparatus to measure the permeability of root dentin after the following sequential steps, with 5 specimens in each: 1) phosphoric acid etching for 30 s (maximum permeability), 2) root planning to create new smear layer, 3) exposure to different acid substances for 5 min (orange, cola drink, vinegar, white wine, lemon juice), 4) toothbrushing with sonic toothbrush for 3 min, 5) toothbrushing with sonic toothbrush plus dentifrice for 3 min. Considering step I as 100%, the data were converted into percentage and each specimen was its own control. Data were analyzed statistically by Kruskal-Wallis and Dunn's post test at 5% significance level. All acidic substances increased dentin permeability significantly after scraping (p< 0.05). Toothbrushing after exposure to acid substances decreased dentin permeability and the association with dentifrice accentuated the decrease (p< 0.05), except for the specimens treated with cola drink. Thus, it may be concluded that all tested acid fruit juices increased dentin permeability, and toothbrushing with or without dentifrice can decrease root dentin permeability after dentin exposure to acid diet.  相似文献   
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