全文获取类型
收费全文 | 3680篇 |
免费 | 161篇 |
国内免费 | 15篇 |
专业分类
耳鼻咽喉 | 127篇 |
儿科学 | 254篇 |
妇产科学 | 272篇 |
基础医学 | 307篇 |
口腔科学 | 84篇 |
临床医学 | 295篇 |
内科学 | 698篇 |
皮肤病学 | 57篇 |
神经病学 | 244篇 |
特种医学 | 113篇 |
外科学 | 850篇 |
综合类 | 61篇 |
一般理论 | 1篇 |
预防医学 | 90篇 |
眼科学 | 96篇 |
药学 | 199篇 |
中国医学 | 8篇 |
肿瘤学 | 100篇 |
出版年
2023年 | 22篇 |
2022年 | 43篇 |
2021年 | 53篇 |
2020年 | 39篇 |
2019年 | 55篇 |
2018年 | 97篇 |
2017年 | 64篇 |
2016年 | 103篇 |
2015年 | 100篇 |
2014年 | 114篇 |
2013年 | 201篇 |
2012年 | 237篇 |
2011年 | 256篇 |
2010年 | 154篇 |
2009年 | 138篇 |
2008年 | 270篇 |
2007年 | 296篇 |
2006年 | 267篇 |
2005年 | 287篇 |
2004年 | 275篇 |
2003年 | 231篇 |
2002年 | 199篇 |
2001年 | 82篇 |
2000年 | 57篇 |
1999年 | 53篇 |
1998年 | 20篇 |
1997年 | 11篇 |
1996年 | 15篇 |
1995年 | 14篇 |
1994年 | 9篇 |
1993年 | 3篇 |
1992年 | 14篇 |
1991年 | 8篇 |
1990年 | 9篇 |
1989年 | 11篇 |
1988年 | 10篇 |
1987年 | 8篇 |
1986年 | 4篇 |
1985年 | 8篇 |
1984年 | 2篇 |
1980年 | 1篇 |
1979年 | 2篇 |
1978年 | 2篇 |
1976年 | 3篇 |
1975年 | 1篇 |
1972年 | 1篇 |
1970年 | 1篇 |
1968年 | 2篇 |
1967年 | 1篇 |
1966年 | 1篇 |
排序方式: 共有3856条查询结果,搜索用时 15 毫秒
51.
Ebru Asicioglu Arzu Kahveci Hakkı Arikan Mehmet Koc Serhan Tuglular Cetin Ishak Ozener 《International urology and nephrology》2013,45(5):1437-1443
Purpose
Atherosclerosis is responsible for the high mortality rate in end-stage renal disease patients. Defining risk factors for atherosclerosis may lead to reduction in cardiovascular disease through modification of these factors. Peritoneal dialysis (PD) patients are subjected to high glucose loads on a daily basis, which results in considerable weight gain and an increase in waist circumference (WC). WC as an indicator of abdominal obesity is a risk factor for atherosclerosis in the general population. Carotid artery intima media thickness (CIMT) measurement is a reliable method for the detection of early atherosclerosis. The aim of this study was to investigate the relationship between WC and CIMT and to define risk factors associated with CIMT in PD patients.Methods
Fifty-five PD patients and 40 healthy controls were included. Atherosclerosis was assessed using measurement of CIMT. Fasting blood was collected for analysis. Anthropometric parameters (age, weight, BMI, and WC) were measured.Results
Peritoneal dialysis patients had higher WC (93.9 ± 1.7 vs. 87.3 ± 1.2 cm, p < 0.05) and CIMT (0.70 ± 0.02 vs. 0.57 ± 0.01 mm, p < 0.01) than the control group. On univariate analysis, age, WC, plaque formation, and D/P creatinine were positively correlated with CIMT, whereas residual renal function, albumin, ultrafiltration volume, and D/D0 glucose were negatively correlated. On multivariate analysis, only age, WC, and plaque formation showed correlation (p < 0.001).Conclusions
Carotid artery intima media thickness is associated with age, plaque formation, and WC in PD patients. WC measurement is a simple, inexpensive, reproducible, and reliable method of evaluating atherosclerosis risk in PD patients and should be assessed at every visit. Appropriate counsel should be provided to patients with greater WC who are deemed to be at risk for atherosclerosis. 相似文献52.
53.
Fuat Ozkan Betul Bakan Mehmet Fatih Inci Fatih Kocturk Gozde Yildirim Cetin Murvet Yuksel Mehmet Sayarlioglu 《REV BRAS REUMATOL》2013,53(4):335-340
ObjectiveThe aim of the present study is to determine the frequency of enthesopathy in fibromyalgia (FM) by using a newly developed ultrasonography (US) method, the Madrid Sonography Enthesitis Index (MASEI).MethodsThis study was conducted on 38 consecutive patients with FM and 48 healthy sex- and age-matched controls. Six entheseal sites (olecranon tuberosity, superior and inferior poles of patella, tibial tuberosity, superior and inferior poles of calcaneus) on both lower limbs were evaluated. All US findings were identified according to MASEI. Scores of patients and controls were compared by Student's t-test and Mann-Whitney U-test. Validity was analysed by receiver operating characteristic curve. Values of P < 0.05 were considered significant.ResultsTotal enthesitis score was 7.39 ± 4.99 (mean ± SD) among FM patients and 3.7 ± 3.22 among healthy controls (P < 0.001). The receiver operating characteristic curve established an ultrasound score of > 3.5 in the FM group as the best cut-off point to differentiate between cases and controls. No statistically significant correlation was found between the MASEI score and the FM disease duration, and the location of the tender points.ConclusionsMisdiagnoses of FM are harmful to patients and the community, and the presence of enthesopathy among FM patients increases. Its detection with the MASEI score may help to discriminate FM patients presenting with ill-defined symptoms and signs, in order to prevent mistreatment. 相似文献
54.
Kemal Agbaht Funda Pepedil Alper Kirkpantur Rahmi Yilmaz Cetin Turgan 《Renal failure》2013,35(1):107-110
Kaposi's sarcoma (KS) is an unusual tumor principally affecting the skin of the lower extremities. Although the association between KS and renal transplant has been well documented, there are a few KS cases in the literature associated with membranoproliferative glomerulonephritis or other glomerular diseases. This report presents a patient with membranoproliferative glomerulonephritis (MPGN) who developed KS following treatment with long-term medium dose glucocorticoid and short-term additional immunosuppressives. The KS cases associated with glomerulonephritis are also reviewed. KS is a rare complication in glomerular diseases that may (or may not) be related to immunosuppression. Hence, immunosuppression treatment should be carefully planned in glomerulonephritis treatment and avoided if they are not essentially necessary. 相似文献
55.
56.
Ugur Coskun Onur Baydar Gurkan Cetin Mehmet Serdar Kucukoglu 《Journal of Echocardiography》2013,11(1):23-25
We report two cases of mechanical prosthetic mitral valve obstruction caused by remnants of the mitral valve posterior leaflet tissue preserved from the previous surgery. Both patients had rheumatic mitral stenosis causing New York Heart Association class III symptoms prior to mitral valve replacement. 相似文献
57.
58.
Ardeshir Ardeshiri Siamak Asgari Elias Lemonas Neriman Oezkan Marc Schlamann Ulrich Sure I. Erol Sandalcioglu 《Clinical neurology and neurosurgery》2013
Objective
Dens fractures are common cervical injuries in advanced aged patients. The presented study was undertaken to analyze the clinical results and risks of surgically treated patients with dens fractures over 70 years.Methods
Data of 28 patients (17 female, 11 male) over 70 years treated from September 2004 to October 2009 were recorded. Clinical and radiological parameters were obtained including type of fracture, associated cervical and/or other injuries, comorbidities, symptoms, neurological condition, surgical strategy, postoperative course and complications.Results
89% were in a good neurological condition before surgery (ASIA E or D). In most cases, surgery was performed at an early stage after trauma (21 patients within 5 days). Ventral screw fixation was the preferred surgical strategy (64%). A slight worsening of neurological functions immediately after operation was only seen in one patient. Five patients died in the early and 2 in the late postoperative course which means a treatment mortality of 25%. Among the surviving patients two had general medical complications.Conclusion
Type II dens fractures are a common fracture of elderly patients. Our results are good concerning the neurological functions. Surgical and general medical complications were acceptable. However, the study also underlines that mortality rate is high and therefore treatment options should be well-considered in this high risk group. 相似文献59.
60.
Hüsniye Aylin Hakyemez Bayram Veyseller Feriha Ozer Serkan Ozben Gulum Ivgin Bayraktar Defne Gurbuz Sibel Cetin Yavuz Selim Yildirim 《Journal of clinical neuroscience》2013,20(10):1469-1470
We aimed to investigate the relationship between olfactory function and olfactory bulbus (OB) volume, disease duration and Unified Parkinson’s disease rating scale (UPDRS) scores in early stage idiopathic Parkinson’s disease patients. The University of Pennsylvania Smell Identification Test (UPSIT) was used for the evaluation of olfactory function. UPSIT scores for patients with Parkinson’s disease were significantly lower than controls. There was no significant difference between stage 1 and stage 2 patients. OB volumes were higher in stage 1 and 2 patients than controls, but there was no statistical difference between the three groups. No significant correlation was found between UPSIT and UPDRS total scores, nor between UPSIT scores and disease duration in stage 1 and 2 patients. According to our results, we propose UPSIT be used as a screening test to diagnose presymptomatic patients, but not OB volumes. 相似文献