全文获取类型
收费全文 | 3404篇 |
免费 | 381篇 |
国内免费 | 42篇 |
专业分类
耳鼻咽喉 | 25篇 |
儿科学 | 148篇 |
妇产科学 | 56篇 |
基础医学 | 330篇 |
口腔科学 | 53篇 |
临床医学 | 493篇 |
内科学 | 848篇 |
皮肤病学 | 78篇 |
神经病学 | 272篇 |
特种医学 | 379篇 |
外科学 | 400篇 |
综合类 | 44篇 |
一般理论 | 1篇 |
预防医学 | 174篇 |
眼科学 | 91篇 |
药学 | 191篇 |
中国医学 | 9篇 |
肿瘤学 | 235篇 |
出版年
2024年 | 9篇 |
2023年 | 71篇 |
2022年 | 57篇 |
2021年 | 105篇 |
2020年 | 129篇 |
2019年 | 60篇 |
2018年 | 149篇 |
2017年 | 115篇 |
2016年 | 109篇 |
2015年 | 106篇 |
2014年 | 158篇 |
2013年 | 208篇 |
2012年 | 168篇 |
2011年 | 151篇 |
2010年 | 142篇 |
2009年 | 173篇 |
2008年 | 117篇 |
2007年 | 143篇 |
2006年 | 128篇 |
2005年 | 103篇 |
2004年 | 86篇 |
2003年 | 76篇 |
2002年 | 67篇 |
2001年 | 78篇 |
2000年 | 48篇 |
1999年 | 72篇 |
1998年 | 96篇 |
1997年 | 108篇 |
1996年 | 88篇 |
1995年 | 77篇 |
1994年 | 57篇 |
1993年 | 53篇 |
1992年 | 50篇 |
1991年 | 30篇 |
1990年 | 36篇 |
1989年 | 68篇 |
1988年 | 58篇 |
1987年 | 37篇 |
1986年 | 32篇 |
1985年 | 22篇 |
1984年 | 22篇 |
1983年 | 18篇 |
1982年 | 17篇 |
1981年 | 16篇 |
1980年 | 17篇 |
1979年 | 9篇 |
1977年 | 9篇 |
1976年 | 11篇 |
1975年 | 8篇 |
1971年 | 8篇 |
排序方式: 共有3827条查询结果,搜索用时 0 毫秒
31.
32.
C. J. Chung V. Bui Lynn A. Fordham Jeannie Hill Dorothy Bulas 《Pediatric radiology》1998,28(5):317-321
Objective. The purpose of this paper is to review and categorize the CT appearances of primary and secondary intraperitoneal neoplasms
in children. Materials and methods. We retrospectively reviewed the CT images of 14 cases of intraperitoneal neoplasms. They were reviewed for bowel wall thickening,
mesenteric nodules, ascites, calcification, peritoneal nodules, omental caking, and contrast enhancement. Results. Computed tomography images of 14 cases of intraperitoneal neoplasms were evaluated: rhabdomyosarcoma (5), lymphoma (3), neuroblastoma
(2), germ cell tumor (1), mesothelioma (1), Wilms tumor (1), and hepatocellular carcinoma (1). Nodular enhancement was seen
in all cases, ascites in most, significant bowel wall thickening only with lymphoma, and calcification only with germ cell
tumors. Omental caking was present both with rhabdomyosarcoma and lymphoma. Conclusions. While rare in pediatrics, intraperitoneal neoplasms occur in children, and CT is useful in identifying these peritoneal neoplasms.
Received: 7 August 1997 Accepted: 9 December 1997 相似文献
33.
Studies have shown family planning adoption is likely to be more effective for women when men are actively involved. The transtheoretical model of behavior change was used to examine men's involvement in general contraception and intrauterine device (IUD) use by their wives. The study was carried out in rural Vietnam with 651 eligible participants. Cons of IUD use for men in precontemplation and contemplation/preparation were significantly higher than those in the action/maintenance stages, whereas the reverse was true for pros of IUD. The self-efficacy for convincing wife to have IUD in precontemplation was significantly lower than for those in higher stages. Women's education and ages, spontaneous recall of modern contraceptive method, cons for IUD, and self-efficacy for contraception and for convincing wives to get IUD inserted (or continue use) were significant predictors of men's readiness to accept IUD. Interventions are targeted to reduce cons and increase self-efficacy for IUD use. 相似文献
34.
Adjuvant radiation therapy for soft tissue sarcoma of the extremities: analysis of local control according to volume and dose] 总被引:1,自引:0,他引:1
Y Milbéo G Kantor H Laharie P Lagarde E Stoeckle F Bonichon L Thomas V Brouste B N Bui 《Cancer radiothérapie》2005,9(5):293-303
PURPOSE: To evaluate retrospectively the anatomical definition of target volumes in the treatment of soft tissue sarcomas of the limbs and to study the radiation dose in the local control and toxicity. METHODS AND PATIENTS: Seventy-seven patients were consecutively treated for primary soft tissue sarcoma of the extremity with limb sparing surgery and external beam radiotherapy (EBRT) in the same institution. The median follow up was 56 months (17-89 months). RESULTS: Fifty-two patients (67%) had clear microscopic surgical margin (R0 resection), 23 (30%) had histologically positive microscopic margin (R1 resection), 2 had a macroscopic residual disease (R2 resection). An anatomical definition of target volumes has been realised. The mean dose was 50 Gy in 25 or 28 fractions; 23 patients received a boost restricted to the tumor bed: 13 with EBRT, 10 with brachytherapy (BRT). Thirty-four patients had an adjuvant chemotherapy. The overall 5 year local relapse rate was 10%. Seven local relapses were described, five of the high-grade tumours, and five in patients with positive margin. In univariate analysis, quality of surgery shows a significant effect for local control. By using LENT-SOMA scale for late toxicity, a significant difference was found for neurological complications for patients receiving a boost. CONCLUSIONS: The results of the series validate the concept of anatomical definition of the initial target volume. A boost should be realised for positive margin tumors and may be for high-grade tumors. Neurological toxicity must be considered for the evaluation of the prescribed dose. 相似文献
35.
Zhong Ning Leonard Goh Roland Yii Lin Teo Bui Khiong Chung Alexis Ching Wong Chen-June Seak 《Medicine》2022,101(31)
Heart failure leading to cardiac ascites is an extremely rare and underrecognized entity in clinical practice. Recognizing cardiac ascites can be difficult, especially since patients presenting with ascites may have more than 1 etiology. Various biomarkers are available to aid in the diagnosis of cardiac ascites, though with differing sensitivities and specificities. Such biomarkers include serum albumin, ascitic albumin and protein, as well as serum N-terminal pro-brain natriuretic peptide (NT-proBNP). While serum NT-proBNP is a powerful biomarker in distinguishing the etiology of ascites and monitoring treatment progression, its cost can be prohibitive in low-resource settings. Clinicians practicing under these circumstances may opt to rely on other parameters to manage their patients. We go on further to report a series of 3 patients with cardiac ascites to illustrate how these biomarkers may be employed in the management of this patient population. Clinicians should always keep in mind the differential diagnosis of cardiac failure as a cause of ascites. The resolution of cardiac ascites may serve as a surrogate clinical marker for response to antifailure therapy in lieu of NT-proBNP at resource-scarce centers. 相似文献
36.
37.
38.
Sulfonic ester is a chemical structure common to many organic molecules, including biologically active compounds. Herein, a visible-light-induced synthetic method to prepare aryl sulfonic ester from arylazo sulfones was developed. In the present study, a one-pot reaction was carried out using arylazo sulfones, DABSO (DABCO·(SO2)2), and alcohols in the presence of CuI as a coupling catalyst and HCl as an additive to yield sulfonic esters via multicomponent reaction. This synthetic method afforded a wide range of sulfonic esters with high yields under mild conditions.Facile and efficient one-pot synthesis of sulfonic esters has been achieved via visible-light-induced multicomponent reaction of arylazo sulfones, and alcohols in the presence of DABSO, CuI, and HCI. 相似文献
39.
40.
Hamady ZZ Malik HZ Finch R Adair R Al-Mukhtar A Prasad KR Toogood GJ Lodge JP 《Annals of surgical oncology》2006,13(11):1493-1499
Background Many colorectal liver metastasis patients are denied surgical resection on the basis of tumour size. The aim of this study was to explore the impact of metastasis size on modern liver resection.Methods Using a prospectively collected database, this was a retrospective analysis of 484 consecutive patients who underwent liver resection for colorectal liver metastases between 1993 and 2003. The cohort was divided into two groups: smaller metastases (<8 cm) and larger metastases (≥ 8 cm). Those with larger metastases were then further stratified into big metastases (8–12 cm) and giant metastases (>12 cm). Demographic, pathological, surgical technique and outcome data were compared between the groups.Results There were 88 (18%) patients with metastases measuring 8 cm or larger. There was an association between higher carcinoembryonic antigen (CEA) and cancer antigen (CA) 19-9 levels and larger metastases. The actuarial 5-year survival for patients with larger metastases was 38% compared with 42% for smaller metastases (not statistically significant). Patients with giant metastases had poorer overall and disease-free survival (both nonsignificant) compared with those with big metastases: 29% and 28% at 5 years, respectively.Conclusion Patients with colorectal liver metastasis greater than 8 cm and up to 12 cm in size should not be treated differently from those with smaller lesions. 相似文献