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排序方式: 共有677条查询结果,搜索用时 31 毫秒
81.
两个小样本对照试验得到的证据尚不足以说明,在Lisfranc关节损伤时,切开复位内固定术(ORIF)的治疗效果要优于I期跗趾关节融合术. 相似文献
82.
Branko J. Brmboli Ivan Borii Dubravka R. Salemovi Djordje Li. Jevtovi Jovan T. Ranin Ana Begi-Janeva 《Liver international》1996,16(3):218-220
Abstract: Tuberculosis of the liver is common in patients with acquired immunodeficiency syndrome (AIDS). Tuberculous liver granulomas in such patients are usually atypical. The liver granulomas may be even totally absent, but liver tissue usually reveals numerous acid-fast bacilli. Focal tuberculosis of the liver is a less common form of liver tuberculous infection. We present a 33-year old white homosexual man infected with the human immunodeficiency virus. He had three tumour-like lesions in the left liver lobe, which were subsequently diagnosed as focal hepatic tuberculosis with local hemorrhage. This unusual presentation of liver tuberculosis indicates the necessity of an aggressive diagnostic approach for the evaluation of focal liver lesions in patients with AIDS. 相似文献
83.
84.
The aim of the study was to define the relevance of deletions and duplications within the DAZ gene cluster to male factor infertility in a population of 90 infertile men and a control of 50 fertile men using real-time polymerase chain reaction (PCR). We conclude that partial deletions of the DAZ genes are associated with oligozoospermia but not with azoospermia; however, an increased number of DAZ genes does not seem to be a statistically significant risk factor for spermatogenic failure. 相似文献
85.
Branko Pikula Pavle Plamenac Borivoje Ćurčić Aleksandar Nikulin 《Virchows Archiv : an international journal of pathology》1973,358(1):99-103
Summary We report a case of primary oxalosis in a 4-year-old boy with intensive deposition of calcium oxalate monohydrate crystals in the kidney and the myocardium. In addition severe fibroplastic inflammatory reaction in form of intensive myocarditis was found. It is an extremely rare complication at this age and represents a particularly rare case of oxalosis. Disorders of oxalate metabolism are discussed in relation to extrarenal deposition of oxalate crystals. 相似文献
86.
David M. Mel Branko Cvjetanovi? Oscar Felsenfeld 《Bulletin of the World Health Organization》1970,43(3):431-437
In earlier studies in man it has been demonstrated that streptomycin-dependent shigellae, if given orally in 5 sufficiently large doses, confer a very high type-specific protection against bacillary dysentery. 相似文献
87.
88.
Grujić J Djurković-Djaković O Nikolić A Klun I Bobić B 《International journal of antimicrobial agents》2005,25(3):226-230
The antitoxoplasmic activity of spiramycin (SPI) was evaluated in murine models of infection using a type-1 (RH) or type-2 (Me49) strain of Toxoplasma gondii. In mice infected with 10(2) tachyzoites of the RH strain, treatment with 100 and 200 mg SPI/kg/day had only a limited effect; despite some dose-dependent prolongation of survival, it was unable to protect mice against death. In contrast, in acute infection induced by peroral inoculation of 10, but not 20, cysts of the Me49 strain, a 3-week course of 100 mg SPI/kg/day and a 4-week course of 200 mg/kg/day significantly enhanced protection and markedly reduced brain cyst burdens at 6 months post infection (p.i.). In chronic infection established by inoculation of 10 cysts 3 months previously, a 3-week course of 200 mg SPI/kg/day resulted in significantly decreased brain cyst burdens compared with controls, both 2 weeks after treatment cessation and by 6 months p.i. Although a favourable effect on chronic infection may be specific for mice, these data merit investigation, since they may have clinical ramifications. 相似文献
89.
90.
Kitazawa M Ohnuma T Takebayashi Y Shibata N Baba H Ohi K Yasuda Y Nakamura Y Aleksic B Yoshimi A Okochi T Ikeda M Naitoh H Hashimoto R Iwata N Ozaki N Takeda M Arai H 《American journal of medical genetics. Part B, Neuropsychiatric genetics》2012,(4):456-464
Recent GWAS demonstrated an association between candidate genes located at region 6p22.1 and schizophrenia. This region has been reported to house certain candidate SNPs, which may be associated with schizophrenia at HIST1H2BJ, PRSS16, and PGBD1. These genes may presumably be associated with pathophysiology in schizophrenia, namely epigenetics and psychoneuroimmunology. A three-step study was undertaken to focus on these genes with the following aims: (1) whether these genes may be associated in Japanese patients with schizophrenia by performing a 1st stage case-control study (514 cases and 706 controls) using Japanese tagging SNPs; (2) if the genetic regions of interest for the disease from the 1st stage of analyses were found, re-sequencing was performed to search for new mutations; (3) finally, a replication study was undertaken to confirm positive findings from the 1st stage were reconfirmed using a larger number of subjects (2,583 cases and 2,903 controls) during a 2nd stage multicenter replication study in Japan. Genotyping was performed using TaqMan PCR method for the selected nine tagging SNPs. Although three SNPs situated at the 3' side of PGBD1; rs3800324, rs3800327, and rs2142730, and two-window haplotypes between rs3800327 and rs2142730 showed positive associations with schizophrenia, these associations did not have enough power to sustain significance during the 2nd stage replication study. In addition, re-sequencing for exons 5 and 6 situated at this region did not express any new mutations for schizophrenia. Taken together these results indicate that the genes HIST1H2BJ, PRSS16, and PGBD1 were not associated with Japanese patients with schizophrenia. 相似文献