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21.
Ingrid Dias Belmiro Freitas de Salles Jefferson Novaes Pablo Brando Costa Roberto Simão 《Journal of Science and Medicine in Sport》2010,12(1):65-69
It is generally recommended that exercises involving large muscle groups be placed at the beginning of a training session. However, methodological training studies manipulating exercise order and the investigation of its influence on strength have not been conducted. Therefore, the purpose of this study was to examine the influence of exercise order on strength in untrained young men after 8 weeks of training. Prior to the training program, participants were randomly assigned to three groups. One group began with large and progressed toward small muscle group exercises (G1) while another performed the opposite order (G2). The third group did not exercise and served as a control (CG). Training frequency was three sessions per week with at least 48 h of rest between sessions for a total of 24 sessions in the 8-week period. One repetition maximum (1RM) was assessed for all exercises at baseline and after 8 weeks of training. Both G1 and G2 resulted in significant increases of 16.3–77.8% in 1RM compared to baseline (p < 0.05). However, only the small muscle group exercises revealed significant differences between groups (p < 0.05). The results demonstrated exercise order of small muscle group exercises might be particularly important during the initial stages of strength training in untrained young men. 相似文献
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23.
M. Airoldi F. Pedani P. Gabriele C. Giordano A. Cavalot V. Brando 《Journal of chemotherapy (Florence, Italy)》2013,25(4):272-276
SummaryThirty-two patients (24 males, 8 females; median age 54 yrs) with recurrent and/or metastatic undifferentiated carcinoma of the nasopharyngeal type were treated with chemotherapy. Remissions were observed in 17 of 32 (53.2%) with 5 complete (CR) (15.6%) and 12 partial responses (PR) (37.6%). A combination of cisplatin and 5-fluorouracil was the most effective regimen (CR + PR = 83.3%). Objective responses. (CR + PR) were 47% (CR=11.7%) in schemes without cisplatin and 60% (CR = 20%) in cisplatin-based combinations. The median overall duration of response was 7.2 months. The median overall survival time was 10.3 months: 15.1 months for responders and 5.2 for non-responders. No important toxicity was observed. 相似文献
24.
Trop-2 induces ADAM10-mediated cleavage of E-cadherin and drives EMT-less metastasis in colon cancer
Emanuela Guerra Marco Trerotola Valeria Relli Rossano Lattanzio Romina Tripaldi Giovanna Vacca Martina Ceci Khouloud Boujnah Valeria Garbo Antonino Moschella Romina Zappacosta Pasquale Simeone Robert de Lange Ulrich H. Weidle Maria Teresa Rotelli Arcangelo Picciariello Raffaella Depalo Patrizia Querzoli Massimo Pedriali Enzo Bianchini Domenico Angelucci Giuseppe Pizzicannella Carla Di Loreto Mauro Piantelli Laura Antolini Xiao-Feng Sun Donato F. Altomare Saverio Alberti 《Neoplasia (New York, N.Y.)》2021,23(9):898
25.
Gomes FS Bastos MA Matozinhos FP Temponi HR Velásquez-Meléndez G 《Revista da Escola de Enfermagem da U S P》2010,44(4):1070-1076
The objective of this a cross-sectional analytical study was to estimate the occurrence of pressure ulcers and their associated factors in adult ICUs in the city of Belo Horizonte, Brazil. The sample consisted of 142 patients aged 18 or older, admitted before midnight of the day prior to data collection, from a total of 316 beds distributed in 22 ICUs. Presence of at least one pressure ulcer per patient was 35.2% (CI 95% = 27.4-47.7). Of the 99 ulcers identified, the ones in the sacral region were most frequent (36.0%), followed by those in the calcaneus (22.0%). We observed that the presence of sepsis (OR = 6.04, CI 95% = 1.09-33.53), period of stay > or = 10 days (OR = 7.61, CI 95% = 2.92-19.82) and being high risk and very high-risk in the Braden scale (OR = 4.96, CI 95% = 1.50-16.50) were independent factors significantly associated with the presence of pressure ulcers. Results suggest that sepsis, length of stay, and having high and very high risk" in the Braden scale are factors potentially associated to the development of ulcers in bedridden patients. 相似文献
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27.
G Busnach A Dal Col B Brando M L Perrino C Brunatti L Minetti 《The International journal of artificial organs》1986,9(4):267-270
Monthly plasma exchange (PE) sessions have been carried out in 3 patients with advanced Waldenstr?m macroglobulinemia, in order to reduce electrophoretic M band under 2g/100 ml. When PE was combined to low doses of cytostatics (n = 18), 3 procedures per session were required to obtain a mean 57.4 +/- 12.3% IgM reduction, from 4.2 +/- 1.2 to 1.7 +/- 0.5 g/100 ml. A mean 61.5 +/- 13.1% IgM reduction, from 5.5 +/- 1.3 to 2.1 +/- 1 g/100 ml, was obtained in 64 procedures carried out as the only therapy in 12 sessions, with 5.3 procedures requirement per monthly session. IgM percent reduction 24 hours after PE was greater with combined treatment (45 +/- 9.7 vs. 28.9 +/- 15.4%; p = 0.001). The advantage of a combined treatment is therefore either a lowered PE requirement or a tapered maintenance cytostatic dosage. 相似文献
28.
Effects of different energy intakes on nitrogen balance in patients with acute renal failure: a pilot study. 总被引:3,自引:0,他引:3
Enrico Fiaccadori Umberto Maggiore Carlo Rotelli Roberto Giacosa Edoardo Picetti Elisabetta Parenti Tiziana Meschi Loris Borghi Dante Tagliavini Aderville Cabassi 《Nephrology, dialysis, transplantation》2005,20(9):1976-1980
BACKGROUND: Thus far, there have been no controlled studies to examine optimal levels of energy provision in critically ill patients with acute renal failure (ARF) receiving artificial nutrition. METHODS: After a 24 h nitrogen-free regimen (20% dextrose), we assigned during an open-label, AB/BA-crossover-trial, 10 ARF patients receiving both total parenteral nutrition (TPN) and renal replacement therapy (seven males; mean age 72 years, range 60-83; mean APACHE II score 27.1, range 23-34, mechanical ventilation 8/10) to a lower calorie-TPN regimen (30 kcal/kg/day) and to a higher calorie-TPN regimen (40 kcal/kg/day), each for 3 days. Nitrogen intake was 0.25 g/kg/day for both regimens. We estimated nitrogen balance, protein catabolic rate and urea generation rate by urea kinetic methods based on both timed blood samples of serum urea and direct urea quantification from dialysis fluid. RESULTS: Two patients were excluded from the analysis (due to death and serum triglycerides above 5.1 mmol/l, respectively). Compared with the lower calorie-TPN, the higher calorie-TPN regimen did not improve estimated nitrogen balance [+1.55 g/day (95% confidence interval: -0.95 to +4.05, P = 0.18)], protein catabolic rate [-0.10 g/kg/day (-0.33 to +0.14, P = 0.35)], or urea generation rate [-1.3 mg/min (-5.2 to +2.7, P = 0.46)], whereas it increased serum triglycerides [+1.36 mmol/l (+0.53 to +2.19, P = 0.007)], glucose [+1.15 mmol/l (+0.07 to +2.24, P = 0.041)], insulin need [+20.4 U/day (+8.3 to +32.6, P = 0.006)] and nutritional fluid administration [+468 ml/day (+370 to +566, P<0.001)]. CONCLUSIONS: The present study, conducted in a small group of subjects, shows that in critically ill patients with ARF on a nitrogen intake of 0.25 g/kg/day, an energy provision of 40 kcal/kg/day does not improve nitrogen balance estimates compared with a 30 kcal/kg/day intake; instead, it may increase the risk of artificial nutrition-related side-effects. 相似文献
29.
We retrospectively analyzed experience with total gastrectomy (TG) for gastric carcinoma in 23 patients. The TNM stage was I in one patient, II in one patient, III in eight patients, and IV in 13. Linitis plastica was found in ten patients. The operation was considered curative in only eight patients (35%). There were 13 complications in eight patients. There were no operative deaths. The survival ranged from three to 36 months. The survival for curative TG was a mean of 21.2 months +/- 3.3 SEM; for palliative TG, mean survival was 10.1 months +/- 1.1 SEM (P less than .001). These results suggest that gastric carcinoma that extensively involves the fundus and/or the corpus continues to be highly lethal, even when these tumors can be resected with a TG. Furthermore, even when the operation is considered "curative" and can be done with little or no operative mortality, the average survival was at best 21 months. 相似文献
30.
Flaviana Bombarda de Andrade Ferreira Sergio Aparecido Torres Odila Pereira da Silva Rosa Cláudio Maniglia Ferreira Roberto Brando Garcia Maria Cristina Marcucci Brenda P F A Gomes 《Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics》2007,104(5):709-716
OBJECTIVE: The aim of this study was to determine the antimicrobial effect of ethanol extract of propolis (EEP) and intracanal medicaments calcium hydroxide, camphorated paramonochlorophenol, and formocresol by means of the macrodilution method using the reinforced clostridial medium (RCM) and brucella and brain heart infusion media. STUDY DESIGN: The antimicrobial agents were sequentially diluted and tested against anaerobic bacteria Prevotella nigrescens, Fusobacterium nucleatum, Actinomyces israelii, and Clostridium perfringens and against Enterococcus faecalis, with the 5 x 10(5) CFU/mL standardized inocula. The tubes were anaerobically incubated and the minimum inhibitory concentration was detected. Blood agar RCM subcultures were performed to provide minimum bactericidal concentration. The results were analyzed by analysis of variance test. RESULTS: All drugs were effective against all tested strains, without statistical differences. E. faecalis was the less susceptible strain, and RCM broth promoted faster bacterial growth, but there were no significant differences in these results. Ethanol did not influence the antimicrobial effect of EEP. 相似文献