A video system for laboratory studies

Instructions on assembling a high-quality and inexpensive microscopy video system that can be made independently are described in the paper. Recommendations on tuning and using the video set are defined alongside with the methods of modernizing the system.     

Cholinopositive Effect of Dilept (Neurotensin Peptidomimetic) as the Basis of Its Mnemotropic Effect

Dilept eliminated learning disturbances in the extrapolation avoidance test, caused by chronic injections of scopolamine alone and in combination with madopar to rats. Dilept improved the dynamics of training and parameters of spatial memory impaired by olfactory bulbectomy (operation causing hypofunction of the central cholinergic system). The detected choline-positive effect of dilept together with pronounced dopaminergic activity necessitate its further development as a drug effective in positive and negative symptoms of schizophrenia and psychotic manifestations of Alzheimer’s disease.__________Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 139, No. 3, pp. 319–324, March, 2005     

The differential diagnosis of intestinal amebiasis

Differential diagnosis of intestinal amebiasis (106 patients), acute Flexner's dysentery (105 patients) and nonspecific ulcerative colitis (31 patients) based on the clinical data and rectoromanoscopic findings is described. Rapidly and gradually progressing in the first 7 days intestinal amebiasis is characterized by a gradual onset, normal t0 with mounting general weakness, celiectasia, diarrhea with hyaloid mucus, focal catarrh-hemorrhagic changes and appearance of individual oval transversal ulcers on the colon mucosa.     

The problems of the modern electrocardiography (to the 100th anniversary of electrocardiography, 1903-2003)

Elucidated in the paper are the key issues of modern electrocardiography (ECG). The negative results of large-scale use of automated ECG interpretation programs are under discussion. The possibility of removing the analogue filters from the electrophysiological apparatus and replacing them with the digital signal processing equipment is contemplated. The modern ECG examinations can not exist without simple automation the program security of information processing. The results of introducing the or apparatus-program complexes (APC) into practice as auxiliary analysis instruments in ECG are analyzed. The effects of APC introduction into daily ECG practice are shown to be advantageous. Finally, there is an analysis of issues related with global computerization in clinical examinations.     

The Effects of Delta Sleep-Inducing Peptide on the Intensity of Lipid Peroxidation and Xanthine Oxidase Activity in Rat Tissues during Cold Stress

Exogenous delta sleep-inducing peptide given i.p. to intact rats at a dose of 12 g/100 g decreased the levels of diene conjugates and Schiff bases in liver and brain tissues and had no effect on xanthine oxidase activity in these tissues. Cold stress was accompanied by increases in xanthine oxidase activity in rat liver and brain, with a consequent accumulation of diene conjugates and Schiff bases, as compared with intact animals. Preliminary administration of delta sleep-inducing peptide before three days of cold stress led to decreases in xanthine oxidase activity and lipid peroxidation products in the liver and brain, as compared with values in stressed rats. The protective effect of delta sleep-inducing peptide in stress is discussed.     

Sensitivity of Gd-DTPA-enhanced MR imaging of benign extraaxial tumors

The effect of gadolinium diethylenetriaminepentaacetic acid (DTPA) on the sensitivity of cranial magnetic resonance (MR) imaging was measured in a prospective blinded study. Twenty-two consecutive patients with benign extraaxial tumors underwent MR imaging on a 1.5-T system without and with intravenous administration of Gd-DTPA. Readers independently interpreted the unenhanced and enhanced images without clinical information. The interpretations were compared with the anatomically verified diagnoses. Gd-DTPA improved the sensitivity of MR imaging for benign extraaxial tumors, especially in cases of residual or recurrent acoustic neuromas, multiple tumors (e.g., neurofibromatosis), or inconclusive unenhanced MR images. Enhancement with Gd-DTPA impaired the identification of a skull base tumor.