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31.
Structure and receptor binding 总被引:42,自引:0,他引:42
32.
Bhatavdekar J Patel D Trivedi C Dave R Nadkarni S Karelia N Vora H Ghosh M Patel S Suthar T Doctor S Balar D 《Oncology reports》1994,1(1):255-257
Hormones are believed to play a dominant role as promoters in the growth and development of hormone-dependent cancers. Much less is known about the circulating hormones in male patients with oesophageal cancer. This lack of attention led us to evaluate the role of peptide and steroid hormones (by RIA) in male patients with oesophageal cancer (n=49). Blood samples of patients were collected pretherapeutically and data was compared with age matched controls (n=25). In this retrospective study, significantly high levels of FSH (P<0.02), LH (P<0.001) and prolactin (P<0.001) were observed with concomitant low levels of estradiol (P<0.001), DHEA-S (P<0.02) and testosterone (P<0.001) in patients when compared with respective controls. The patients when grouped according to anatomical site and histological type of the tumor, intergroup variation was not observed in these hormones. From our, study, it seems that hormonal imbalance or altered ratio of peptide and steroid hormones might be playing a significant role in the development and/or progression of oesophageal carcinoma in men. 相似文献
33.
Mukhopadhyay AK Dave JN Vora NS Shah SV Ghosh A Cardoso BJ 《Indian journal of dermatology, venereology and leprology》1995,61(3):176-177
A two-and-half month-old female infant with cavernous haemangioma, agenesis and syndactyly of toes, microophthalmia and microcornea is reported. 相似文献
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S. C. Mishra S. K. Sardana V. S. Dave 《Indian journal of otolaryngology and head and neck surgery》1978,30(2):65-67
Abnormal vestibular responses are observed more frequently in cerebellar and Brain stem lesions than in cerebello-pontine angle tumours. The direction of spontaneous, positional, positioning nystagmus or caloric induced directional preponderance are not quite reliable in topographical localisation of these lesions. Hyperreflexia and dysarhythmia of thermally induced nystagmus are reasonably reliable evidences of affections of cerebellum or its connections. The deficiency of the fast phase of nystagmus indicates a bulbopontine lesion. 相似文献
36.
Complicated stent supported cerebrovascular angioplasty: case analyses and review of literature 总被引:2,自引:0,他引:2
Koenigsberg RA Dave A McCormick D Weiss J Higashida RT Faro SH Grandinetti LM Tsai FY 《Surgical neurology》2000,53(5):465-474
BACKGROUND: Hemodynamic lesions of the cervicocerebral vasculature are currently being treated with stent supported percutaneous transluminal angioplasty. These procedures have met with increasing success when compared to the risks and morbidity of more invasive surgical approaches. The versatility of stent-supported angioplasty as a primary therapeutic modality is examined in the following complex cases. CASE DESCRIPTION: We present four cases involving cervical angioplasty with emergent or adjunctive stent placement. Two cases involved the subclavian arteries, whereas the others involved the vertebral and internal carotid arteries. In our experience, complications of cervicocerebral artery angioplasty have been successfully managed by stent placement. CONCLUSION: Our cases demonstrate the emerging role of cervical angioplasty and stent implantation as a successful therapeutic modality, highlighted in these complex cases. 相似文献
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Morgan C. Willson Emily C. Bell Sanjay Dave Sheila J. Asghar Brent M. McGrath Peter H. Silverstone 《European neuropsychopharmacology》2005,15(6):633-639
Dextroamphetamine administration in healthy controls produces a range of subjective and physiological effects, which have been likened to those occurring during mania. However, it is uncertain if these can be attenuated by lithium since conflicting results have been reported. To date there have been no previous studies examining the effects of valproate on dextroamphetamine-induced mood and physiological changes. The current study was a double-blind, placebo-controlled, study in which volunteers received either 1000 mg sodium valproate (n = 12), 900 mg lithium (n = 9), or placebo (n = 12) pre-treatment for 14 days. Subjective and physiological measures were then obtained prior to administration of a 25 mg dose of dextroamphetamine, and at two time points after administration. Differences in the response to dextroamphetamine were assessed between the three treatment groups. The results of this study show that pre-treatment with lithium only significantly attenuated dextroamphetamine-induced change in happiness, while valproate pre-treatment significantly attenuated the effects of dextroamphetamine on happiness, energy, alertness and on the diastolic blood pressure. These results suggest that lithium and valproate do not have the same mechanism of action on dextroamphetamine-induced changes, and this finding may relate to differences in their mechanism of action in mood disorders. 相似文献