全文获取类型
收费全文 | 1545篇 |
免费 | 81篇 |
国内免费 | 13篇 |
专业分类
耳鼻咽喉 | 9篇 |
儿科学 | 93篇 |
妇产科学 | 103篇 |
基础医学 | 121篇 |
口腔科学 | 42篇 |
临床医学 | 167篇 |
内科学 | 332篇 |
皮肤病学 | 45篇 |
神经病学 | 24篇 |
特种医学 | 145篇 |
外科学 | 119篇 |
综合类 | 135篇 |
预防医学 | 94篇 |
眼科学 | 10篇 |
药学 | 90篇 |
1篇 | |
中国医学 | 74篇 |
肿瘤学 | 35篇 |
出版年
2021年 | 15篇 |
2020年 | 10篇 |
2018年 | 12篇 |
2017年 | 18篇 |
2016年 | 14篇 |
2015年 | 33篇 |
2014年 | 42篇 |
2013年 | 42篇 |
2012年 | 48篇 |
2011年 | 46篇 |
2010年 | 55篇 |
2009年 | 44篇 |
2008年 | 43篇 |
2007年 | 33篇 |
2006年 | 38篇 |
2005年 | 16篇 |
2004年 | 21篇 |
2003年 | 13篇 |
2002年 | 13篇 |
2001年 | 23篇 |
2000年 | 10篇 |
1999年 | 19篇 |
1998年 | 44篇 |
1997年 | 55篇 |
1996年 | 48篇 |
1995年 | 43篇 |
1994年 | 55篇 |
1993年 | 35篇 |
1992年 | 17篇 |
1991年 | 15篇 |
1990年 | 15篇 |
1989年 | 28篇 |
1988年 | 27篇 |
1987年 | 30篇 |
1986年 | 25篇 |
1985年 | 17篇 |
1984年 | 16篇 |
1983年 | 17篇 |
1982年 | 13篇 |
1981年 | 23篇 |
1980年 | 16篇 |
1959年 | 35篇 |
1958年 | 58篇 |
1957年 | 87篇 |
1956年 | 45篇 |
1955年 | 75篇 |
1954年 | 67篇 |
1953年 | 17篇 |
1952年 | 14篇 |
1949年 | 10篇 |
排序方式: 共有1639条查询结果,搜索用时 0 毫秒
91.
92.
PETRERE JUDITH A.; HUMPHREY RONALD R.; ANDERSON JOHN A.; FITZGERALD JAMES E.; DE LA IGLESIA FELIX A. 《Toxicological sciences》1985,5(4):665-671
Studies on Reproduction in Rats with Meclofenamate Sodium, aNonsteroidal Anti-inflammatory Agent. PETRERE, J. A., HUMPHREY,R. R., ANDERSON, J. A., FITZGERALD, J. E., AND DE LA IGLESIA,F. A. (1985). Fundam. Appl. Toxicol. 5, 665671. Reproductionand teratology studies were performed in rats given meclofenamatesodium, a nonsteroidal anti-inflammatory agent. Dosages of 0,3, 6, and 9 mg/kg were administered orally as dietary admixturesin the Fertility and Perinatal-Postnatal studies. In the Teratologystudy, dosages of 10, 12, 15, and 20 mg/kg were administeredby intragastric intubation. In the Male-Fertility study no adverseeffects on fertility or litter and offspring parameters wereobserved in two generations. In the Female-Fertility and Perinatal-Postnatalstudies, maternal toxicity (death associated with intestinalulceration and adhesions) was particularly evident during lactation.Prolonged gestation periods, decreased weanling weights, andincreased weanling mortality were evident at dosages of 6 and9 mg/kg. Increased postimplantation loss occurred at 6 and 9mg/kg in the Term Sacrifice subgroup of the Female-Fertilitystudy. Fertility rates were unaffected and all other litterand offspring parameters of the F1 and F2 generations appearednormal. In the Teratology study no adverse effects on embryonicor fetal development were evident at maternally toxic dosagesup to 20 mg/kg. © 1985 Society of Texicology. 相似文献
93.
94.
目的:探讨HBV-DNA复制水平与肝纤维化之间的相关性。方法:对210例慢性乙型肝炎患者进行HBV-DNA和肝纤维化血清学标志透明质酸(HA)、层粘蛋白(LN)、III型前胶原(PCIII)、IV型胶原(IV-C)进行定量检测。应用SPSS10.0统计软件对结果数据进行分析处理。结果:随慢性乙肝临床类型的加重,肝纤维化血清学标志逐渐升高(P<0.01),而肝纤维化血清学标志与HBV复制水平呈正相关(P<0.05);结论:HBV复制水平与肝纤维化之间呈正相关。 相似文献
95.
96.
97.
98.
目的:研究秦艽醇提取物的抗炎及镇痛作用。方法:采用二甲苯致小鼠耳廓肿胀,角叉菜胶致大鼠足趾肿胀及冰醋酸致小鼠扭体反应,观察秦艽醇提物的抗炎及镇痛作用。结果:秦艽醇提物能降低二甲苯炎症模型小鼠的耳廓肿胀度(P<0.01),对角叉菜胶模型大鼠的急性炎症有一定的抑制作用,从第3小时起足趾容积和肿胀度与模型组比较具有统计学意义(P<0.05),秦艽醇提物还能提高小鼠的痛阈,减少冰醋酸致小鼠扭体次数,与模型组比较具有统计学意义(P<0.05)。结论:秦艽醇提物对二甲苯及角叉菜胶所致的炎症具有一定的抑制作用,同时具有明显的镇痛作用。 相似文献
99.
100.
3-Hydroxypropyl flufenamide (Flu-HPA) is one of a series of flufenamic acid derivatives that enhances blood clot lysis in vitro. Studies of possible mechanisms of action of Flu-HPA were undertaken. The profibrinolytic activity of Flu-HPA in clot lysis assays was found to be dependent on plasminogen. The influence of Flu-HPA on the ability of purified alpha 2-antiplasmin to inhibit purified plasmin was studied. Plasmin activity was determined using 125I-fibrin plates or the spectrophotometric tripeptide substrate, Val-Leu-Lys-paranitroanilide. At Flu-HPA concentrations greater than 1 mM, the inhibitory activity of alpha 2-antiplasmin was abolished in a time-dependent and concentration- dependent manner. The influence of Flu-HPA on the ability of purified Cl inhibitor to inhibit purified plasma kallikrein and beta-Factor XIIa was also studied. Cl inhibitor activity was abolished by Flu-HPA at concentrations greater than 2 mM. Notably, Flu-HPA up to 60 mM did not affect the amidolytic activities of plasmin, kallikrein, or beta-Factor XIIa. Flu-HPA did not release enzyme activity from preformed complexes of either alpha 2-antiplasmin and plasmin of Cl inhibitor and kallikrein. A water-soluble derivative of flufenamic acid, N-flufenamyl- glutamic acid, also inactivated alpha 2-antiplasm and Cl inhibitor. This inactivation was shown to be reversible. These results indicate that synthetic fibrinolytic compounds such as flufenamic acid derivatives may promote fibrinolysis by directly inactivating alpha 2- antiplasmin and Cl inhibitor. 相似文献