Experience of closed screwing of intraarticular fractures of the calcaneum. Operation technique and clinical outcome

Summary For the closed treatment of an intraarticular fracture of the heelbone it is essential to know the 3D shape of the bone, the various types of fractures and to get skilled in reduction under an image intensifier. In our hospital we have made a comparison of 34 fractures treated with a plate and 94 treated with screws. The evaluation was made by the scores based on Merle d'Aubigne and clinical and radiological findings. The method of closed reduction and fixation with screws is easier, less dangerous for the patient and, compared to the open fixation, the results are the same or even better (good and excellent: 79,7 %). As a result of gentle treatment of the soft tissues and the early reposition, the wound healing complications decreased to 2,1 % compaired to the 14 % healing problems connected to open plating. Furthermore, cancellous grafting was necessary within the first group.      

Effects of prenatal gamma-irradiation on postnatal astrogliogenesis in the hippocampal formation of rat

Female Wistar rats were exposed to a single 1.0 Gy dose of gamma radiation on gestational days 13, 15, 17 or 19 (E13, E15, E17 and E19, respectively). Their 8- and 16-day old male offsprings were injected with ³H-thymidine and sacrificed 4 h after the injection. Brain sections were immunostained for S100β protein and subjected to autoradiography. Thereafter, the dorsal part of the hippocampal formation was examined microscopically and numbers and locations of proliferating astrocytes were recorded. Following prenatal irradiation, the intensity of astrocyte proliferation was considerably reduced, especially in the region of dentate gyrus. The reduction showed regular trend of changes being much stronger in brains irradiated on E19 than in those irradiated on E13. The changes, therefore, were related to the stage of brain development at which the irradiation was performed. A possible role of neuronal regulatory influence on the postnatal development of glial cells was discussed.     

Structural and functional MRI in children with renal disease: First experience

PurposeThis MRI study demonstrates our first clinical experiences with structural and functional evaluation in children with renal dysfunction, and communicates our experience with quantitative measurements of renal function compared to reference values found employing radionucleotides.Material and methodsWe included renal impaired children who were recruited for clinical radioisotopic GFR measurements (n=8). MRI was performed 2 hours after Cr-EDTA measurements and was conducted using a protocol involving both anatomical/structural sequences and a dynamic contrast-enhanced sequence. Data obtained with the dynamic MRI sequence were processed using the graphical Patlak approach to obtain estimates of GFR.ResultsWe were able to characterize the intrarenal configuration (cortex, medulla, pelvicalyceal arrangement) in all cases. Functional analyses of dynamic contrast-enhanced MRI revealed an overall underestimation of GFR measured by MRI compared to Cr-EDTPA measures (range: ?2% to ?43%).ConclusionsWe advocate the use of MRI as a single-modality approach in the structural and functional evaluation of impaired kidneys in children, and concurrently, we presented a clinically available strategy for estimations of renal cortical volume and single kidney function. However, the use of MRI contrast agents have recently become controversial in renal patients due to the risk of NSF.     

Cotard’s syndrome: A review

Cotard’s syndrome is a rare disorder in which nihilistic delusions concerning one’s own body are the central feature. It is not listed as a specific disorder in the DSM-IV, as it is typically viewed as a part of other underlying disorders. However, it remains important to recognize the syndrome because specific underlying mechanisms are present, and prognostic and therapeutic consequences have to be taken into account. This review presents an up-to-date overview of Cotard’s syndrome, which was initially described more than a century ago.     

Ueber die psychologischen Grundlagen der Vergleichung gehobener Gewichte

Ohne Zusammenfassung     

über die Beeinflussung der Schmerzempfind-Lichkeit der Haut Durch Quarzlampen-Bestrahlung

Ohne ZusammenfassungAusführl. Mitteil. erscheint in der Zeitschr. f. d. ges. exp. Med.