全文获取类型
收费全文 | 6935篇 |
免费 | 402篇 |
国内免费 | 40篇 |
专业分类
耳鼻咽喉 | 141篇 |
儿科学 | 251篇 |
妇产科学 | 67篇 |
基础医学 | 845篇 |
口腔科学 | 80篇 |
临床医学 | 642篇 |
内科学 | 1909篇 |
皮肤病学 | 98篇 |
神经病学 | 611篇 |
特种医学 | 232篇 |
外国民族医学 | 10篇 |
外科学 | 1141篇 |
综合类 | 37篇 |
预防医学 | 368篇 |
眼科学 | 65篇 |
药学 | 430篇 |
中国医学 | 6篇 |
肿瘤学 | 444篇 |
出版年
2023年 | 36篇 |
2022年 | 57篇 |
2021年 | 132篇 |
2020年 | 75篇 |
2019年 | 135篇 |
2018年 | 178篇 |
2017年 | 120篇 |
2016年 | 136篇 |
2015年 | 174篇 |
2014年 | 216篇 |
2013年 | 285篇 |
2012年 | 455篇 |
2011年 | 441篇 |
2010年 | 233篇 |
2009年 | 237篇 |
2008年 | 372篇 |
2007年 | 368篇 |
2006年 | 425篇 |
2005年 | 387篇 |
2004年 | 334篇 |
2003年 | 350篇 |
2002年 | 313篇 |
2001年 | 135篇 |
2000年 | 145篇 |
1999年 | 125篇 |
1998年 | 77篇 |
1997年 | 54篇 |
1996年 | 64篇 |
1995年 | 40篇 |
1994年 | 39篇 |
1993年 | 36篇 |
1992年 | 108篇 |
1991年 | 93篇 |
1990年 | 72篇 |
1989年 | 81篇 |
1988年 | 60篇 |
1987年 | 90篇 |
1986年 | 66篇 |
1985年 | 73篇 |
1984年 | 47篇 |
1983年 | 47篇 |
1982年 | 25篇 |
1981年 | 25篇 |
1979年 | 49篇 |
1976年 | 27篇 |
1974年 | 31篇 |
1973年 | 36篇 |
1972年 | 27篇 |
1971年 | 37篇 |
1970年 | 23篇 |
排序方式: 共有7377条查询结果,搜索用时 0 毫秒
91.
Kimberly A Bertrand Rulla M Tamimi Christopher G Scott Matthew R Jensen V Shane Pankratz Daniel Visscher Aaron Norman Fergus Couch John Shepherd Bo Fan Yunn-Yi Chen Lin Ma Andrew H Beck Steven R Cummings Karla Kerlikowske Celine M Vachon 《Breast cancer research : BCR》2013,15(6):R104
Introduction
Understanding whether mammographic density (MD) is associated with all breast tumor subtypes and whether the strength of association varies by age is important for utilizing MD in risk models.Methods
Data were pooled from six studies including 3414 women with breast cancer and 7199 without who underwent screening mammography. Percent MD was assessed from digitized film-screen mammograms using a computer-assisted threshold technique. We used polytomous logistic regression to calculate breast cancer odds according to tumor type, histopathological characteristics, and receptor (estrogen receptor (ER), progesterone receptor (PR), human epidermal growth factor receptor (HER2)) status by age (<55, 55–64, and ≥65 years).Results
MD was positively associated with risk of invasive tumors across all ages, with a two-fold increased risk for high (>51%) versus average density (11-25%). Women ages <55 years with high MD had stronger increased risk of ductal carcinoma in situ (DCIS) compared to women ages 55–64 and ≥65 years (Page-interaction = 0.02). Among all ages, MD had a stronger association with large (>2.1 cm) versus small tumors and positive versus negative lymph node status (P’s < 0.01). For women ages <55 years, there was a stronger association of MD with ER-negative breast cancer than ER-positive tumors compared to women ages 55–64 and ≥65 years (Page-interaction = 0.04). MD was positively associated with both HER2-negative and HER2-positive tumors within each age group.Conclusion
MD is strongly associated with all breast cancer subtypes, but particularly tumors of large size and positive lymph nodes across all ages, and ER-negative status among women ages <55 years, suggesting high MD may play an important role in tumor aggressiveness, especially in younger women. 相似文献92.
Assessment and predictors determination of indoor airborne fungal concentrations in Paris newborn babies' homes 总被引:2,自引:0,他引:2
Dassonville C Demattei C Detaint B Barral S Bex-Capelle V Momas I 《Environmental research》2008,108(1):80-85
Indoor mould growth can affect health, especially in early childhood. As part of a birth cohort follow-up, the purpose of this study was firstly to examine spectrum and levels of airborne fungi in 190 Paris newborns’ dwellings, and secondly to identify predictors of these levels. Sequential duplicate air samples were collected twice a year in the newborn's bedroom and outside the building. A single-stage multi-holed impactor (Air Ideal®) was used with chloramphenicol/MEA agar. Housing characteristics were assessed using a questionnaire administered by a trained interviewer. Cladosporium and Penicillium were isolated in, respectively, 77% and 93% of homes in the cold season, and in 95% and 83% of homes in the hot season. Aspergillus and Alternaria were recovered from indoor air in, respectively, 60% and less than 20% of homes. Geometric means (geometric standard deviation) of indoor total airborne fungal concentrations at two different visits were, respectively, 232.4 (3.2) and 186.7 (2.7) cfu/m3. In the GEE multivariate analysis, outdoor fungal concentrations were the best predictors for variability of indoor total fungal and Cladosporium concentrations (respectively, R2=32% and 31%). Levels of total airborne fungal and Cladosporium concentrations were significantly higher during the hot season (respectively, p=0.003 and p<0.001) and were positively correlated with the duration of bedroom aeration (respectively, p=0.004 and p<0.001). Signs of dampness were associated with higher total airborne fungi (p=0.031) and Aspergillus levels (p=0.055). This study provides for the first time indoor airborne fungal spectrum and concentrations in Paris. Outdoor levels and season largely contributed to the variability of indoor total airborne fungal concentrations, which also depended on aeration and signs of dampness. 相似文献
93.
Chronic splenomegaly in Nairobi, Kenya. II. Portal hypertension 总被引:1,自引:0,他引:1
K M De Cock S Awadh R S Raja B M Wankya R A Jupp B Slavin T K Arap Siongok P H Rees J Bertrand S B Lucas 《Transactions of the Royal Society of Tropical Medicine and Hygiene》1987,81(1):107-110
Eighty-five patients with chronic splenomegaly and proven oesophageal varices were studied at Kenyatta National Hospital, Nairobi. The major defined groups were hepatosplenic schistosomiasis (24%), cirrhosis (20%) and portal vein occlusion (11%). Hyper-reactive malarial splenomegaly (tropical splenomegaly syndrome) was considered as the cause of oesophageal varices in only one patient. In 26% of cases liver biopsy was non-diagnostic and the extrahepatic portal vein was demonstrated radiologically to be patent. Such patients were thought to be suffering from idiopathic portal hypertension, not previously described elsewhere in Africa. Hepatitis B surface antigen was detected in 12% of controls and in 58% of patients with cirrhosis (p less than 0.001). Some serological marker of previous hepatitis B virus infection was present in 92% of patients with cirrhosis and in 79% of controls. Kamba patients from Machakos and Kitui Districts were significantly more prevalent than expected among these 85 cases of portal hypertension. 相似文献
94.
Florent Le Bars Remy Pascot Charles Ricordel Herve Corbineau Jean Philippe Verhoye Bertrand Richard De Latour Simon Rouze 《中华创伤杂志(英文版)》2020,23(3):185-186
Thoracic splenosis is the autotransplantation of splenic tissue in the left thoracic cavity as a result of a splenic injury. This rare pathology is usually asymptomatic and may be discovered on incidental imaging, but the diagnosis often requires invasive procedures such as surgery in order to eliminate a neoplasic origin. We report a rare symptomatic case of a 39-year-old man presenting with chest pain and multiple nodules revealed on a computed tomography scan. The patient underwent a surgical exploration and the pathological studies concluded to a thoracic splenosis. Indeed, the previous medical history of the patient revealed a left thoraco-abdominal traumatism during childhood. The aim of this paper is to emphasize
that the diagnosis can now be performed using only imaging techniques such as technetium-99 sulfur colloid or labelled heat-denatured red blood cell scintigraphy to avoid unnecessary invasive procedures including thoracotomy. 相似文献
95.
Impact of a change in protected environment on the occurrence of severe bacterial and fungal infections in children undergoing hematopoietic stem cell transplantation 下载免费PDF全文
96.
97.
Vincristine efficacy and safety in treating immune thrombocytopenia: a retrospective study of 35 patients 下载免费PDF全文
Jérôme Stirnemann Najett Kaddouri Medhi Khellaf Anne‐Sophie Morin Virginie Prendki Marc Michel Arsène Mekinian Philippe Bierling Pierre Fenaux Bertrand Godeau Olivier Fain 《European journal of haematology》2016,96(3):269-275
Although vincristine (VCR) is sometimes prescribed for newly diagnosed immune thrombocytopenia (ITP), its efficacy in refractory ITP and sustained efficacy has yet to be demonstrated. We describe our clinical experience and recommend vincristine's correct place in ITP management. This retrospective study analysed data from 35 patients with newly diagnosed (ND), persistent (P) or chronic (C) ITP treated with VCR. The initial response rate, defined as >30 × 109 platelets/L, reached 86% after a median of 7 [interquartile range (IQR) 6–13] days. In ND and P ITP, even when previous therapies were inefficient, initial response was 87.5%, suggesting that this treatment could be used particularly in rescue. Median survival time, without failure or relapse, was 15 months (Kaplan–Meier curve). Predictive factors (univariate analysis) of an initial and long‐term response were a small number of prior treatments received. However, at 2 yr, only seven patients had sustained response. Eight (23%) patients experienced adverse events: neuropathy for seven and bowel obstruction for one. Vincristine efficacy in ITP was confirmed, and it could be a good strategy for treating resistant ITP, especially in emergencies. In this era of new therapeutics, VCR deserves to remain on the list of ITP treatments because of its initial efficacy, safety and low cost. 相似文献
98.
99.
100.
Naïka C. Gabriel Elizabeth Sloand Faye Gary Mona Hassan Desiree R. Bertrand Jacquelyn Campbell 《Health care for women international》2016,37(7):773-789
The purpose of this study was to explore the perceptions of violence against women (VAW) held by Haitian men to gain a better understanding of why VAW occurs. Women in Haiti have experienced significant violence, both before and following the 2010 earthquake. Fifteen men aged 26 to 47 participated in a focus group. The data revealed three themes: men's beliefs about VAW and its context, factors influencing VAW, and recommended interventions. When approaching VAW, men must be part of the collective effort. Their insights are valuable when planning and implementing interventions to decrease VAW in Haiti and worldwide. 相似文献