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Analysis of these results shows that complete hard tissue bridges, aside from occurring with great frequency, produce a satisfactory protection to the pulp. In a case in which the barrier is incomplete, some future clinical problems may result as an incomplete barrier does not offer adequate protection as shown by the chronic inflammatory reaction in the remaining pulp tissue.  相似文献   
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The purpose of this study was to compare the reaction of rat subcutaneous connective tissue to 0.9% sterile saline, 2.5% sodium hypochlorite (NaOCl), 5.25% NaOCl and 2% chlorhexidine gluconate solution or gel. Six circles were demarcated on the dorsal skin of 24 male Wistar rats, leaving 2 cm between each circle. Using a syringe, 0.1 mL of each root canal irrigant was injected subcutaneously into 5 circles. In the 6th circle, the needle of an empty syringe was introduced into the skin, but no irrigant was injected (control group). Evaluations were undertaken at 2 h, 48 h, 14 days and 30 days post-procedure. Tissue samples were excised, embedded in paraffin blocks and 3-μm-thick sections were obtained and stained with hematoxylin and eosin. The areas of inflammatory reaction were evaluated and analyzed statistically by ANOVA and Tukey''s test. The control group showed few or no inflammatory reaction areas in the subcutaneous tissue. 0.9% saline solution, 2.0% chlorhexidine solution and 2.5% NaOCl showed a good biocompatibility, as very mild inflammatory reaction was detected at 14 days and tissue repair occurred at 30 days. 5.25% NaOCl was the most toxic irrigant, as the number of inflammatory cells remained elevated at 14 and 30 days. The group treated with 2.0% chlorhexidine gluconate gel presented a moderate inflammatory response at 14 days, which decreased at 30 days, being considered similar to that of the control group, 0.9% saline solution, 2.0% chlorhexidine solution and 2.5% NaOCl at this experimental period.  相似文献   
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There is inconclusive evidence on the value of regular dental attendance. This study explored the relationship between long‐term patterns of dental attendance and caries experience. We used retrospective data from 3,235 adults, ≥16 yrs of age, who participated in the Adult Dental Health Survey in the UK. Participants were classified into four groups (always, current, former, and never regular‐attenders) based on their responses to three questions on lifetime dental‐attendance patterns. The association between dental‐attendance patterns and caries experience, as measured using the decayed, missing, or filled teeth (DMFT) index, was tested in negative binomial regression models, adjusting for demographic (sex, age, and country of residence) and socio‐economic (educational attainment, household income, and social class) factors. A consistent pattern of association between long‐term dental attendance and caries experience was found in adjusted models. Former and never regular‐attenders had a significantly higher DMFT score and numbers of decayed and missing teeth, but fewer filled teeth, than always regular‐attenders. No differences in DMFT or its components were found between current and always regular‐attenders. The findings of this study show that adults with different lifetime trajectories of dental attendance had different dental statuses.  相似文献   
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Rosel E, Tsakos G, Bernabé E, Sheiham A, Bravo M. Assessing the level of agreement between the self‐ and interview‐administered Child‐OIDP. Community Dent Oral Epidemiol 2010; 38: 340–347. © John Wiley & Sons A/S Abstract –  Objective: To assess the level of agreement between the self‐ and interviewer‐administered Child version of the Oral Impacts on Daily Performances (Child‐OIDP) index. Methods: This was a randomised study in 177 children aged 10–13 years from Granada (Spain). All children completed both administration modes of the Child‐OIDP; half the sample received the interviewer‐administered version first (n = 90), and the other half the self‐administered version first (n = 87). This was done to address potential order effects due to the sequential administration of both instruments. The level of agreement between both modes of administration was assessed with the Bland and Altman method for the Child‐OIDP score and Kappa for the prevalence of oral impacts. Results: The two groups did not differ in their socio‐demographic characteristics or self‐perceived oral health measures. No order effects were found. There was no significant difference between the two modes of administration in terms of the overall score and prevalence of oral impacts (P 0.784 in both cases). The mean difference in Child‐OIDP scores was 0.03 (95% CI = ?0.29 to 0.35) and the 95% limits of agreement were ?6.32 and 4.93. Kappa value for the prevalence of impacts was 0.92. Conclusions: The self‐ and interviewer‐administered Child‐OIDP had a high level of agreement, irrespectively of whether the overall score or the prevalence of oral impacts was used to describe children’s quality of life.  相似文献   
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