全文获取类型
收费全文 | 5395篇 |
免费 | 354篇 |
国内免费 | 25篇 |
专业分类
耳鼻咽喉 | 50篇 |
儿科学 | 225篇 |
妇产科学 | 215篇 |
基础医学 | 724篇 |
口腔科学 | 103篇 |
临床医学 | 624篇 |
内科学 | 1060篇 |
皮肤病学 | 168篇 |
神经病学 | 373篇 |
特种医学 | 150篇 |
外国民族医学 | 2篇 |
外科学 | 575篇 |
综合类 | 72篇 |
一般理论 | 4篇 |
预防医学 | 569篇 |
眼科学 | 166篇 |
药学 | 361篇 |
中国医学 | 5篇 |
肿瘤学 | 328篇 |
出版年
2023年 | 65篇 |
2022年 | 112篇 |
2021年 | 212篇 |
2020年 | 140篇 |
2019年 | 171篇 |
2018年 | 236篇 |
2017年 | 177篇 |
2016年 | 176篇 |
2015年 | 157篇 |
2014年 | 242篇 |
2013年 | 335篇 |
2012年 | 440篇 |
2011年 | 444篇 |
2010年 | 217篇 |
2009年 | 147篇 |
2008年 | 307篇 |
2007年 | 366篇 |
2006年 | 285篇 |
2005年 | 313篇 |
2004年 | 219篇 |
2003年 | 197篇 |
2002年 | 162篇 |
2001年 | 35篇 |
2000年 | 27篇 |
1999年 | 26篇 |
1998年 | 22篇 |
1997年 | 28篇 |
1996年 | 24篇 |
1995年 | 18篇 |
1994年 | 13篇 |
1993年 | 22篇 |
1992年 | 19篇 |
1991年 | 14篇 |
1990年 | 17篇 |
1989年 | 21篇 |
1988年 | 20篇 |
1987年 | 25篇 |
1986年 | 21篇 |
1985年 | 27篇 |
1983年 | 12篇 |
1982年 | 12篇 |
1981年 | 13篇 |
1980年 | 15篇 |
1976年 | 9篇 |
1975年 | 9篇 |
1971年 | 10篇 |
1970年 | 16篇 |
1969年 | 13篇 |
1967年 | 9篇 |
1960年 | 9篇 |
排序方式: 共有5774条查询结果,搜索用时 31 毫秒
71.
Kristine Lund Jenny Hultqvist Ulrika Bejerholm Elisabeth Argentzell Mona Eklund 《Scandinavian journal of occupational therapy》2020,27(6):462-473
AbstractBackground: There exist few recovery and occupation-based interventions for mental health service users. Balancing Everyday Life (BEL) is a new occupation-based lifestyle intervention that was created to fill this need.Aim: To gain group leaders’ and participants’ perspectives of the BEL intervention content and format, including factors that helped, hindered, and could be improved.Methods: A constructivist grounded theory method guided data collection and analysis. Interviews took place with 12 BEL group leaders and 19 BEL participants from out-patient psychiatry settings and community-based day centers in Sweden.Results: BEL’s structure and content were appreciated, yet flexibility was desired to adapt to participant needs. BEL could act as a bridge, helping participants connect with others, and to a more engaged and balanced everyday life. Facilitating factors included a person-focused (versus illness-focused) approach, physical and emotional environments, and connection. Barriers included room resources. More sessions were desired for the intervention.Conclusion: Group leaders and participants experienced BEL as a useful tool to instigate meaningful change and connection in the participants’ lives. The combination of a positive person-focused approach and group support was appreciated. These results could inform future research, evaluation, and development of occupation-focused lifestyle interventions for mental health service users. 相似文献
72.
Novel mutation in LIPH in a Lebanese patient with autosomal recessive woolly hair/hypotrichosis
下载免费PDF全文
![点击此处可从《The Journal of dermatology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
73.
Report of a newly indentified patient with mutations in BMP1 and underlying pathogenetic aspects
下载免费PDF全文
![点击此处可从《American journal of medical genetics. Part A》网站下载免费的PDF全文](/ch/ext_images/free.gif)
74.
HE4 as a predictor of adjuvant chemotherapy resistance and survival in patients with epithelial ovarian cancer
下载免费PDF全文
![点击此处可从《APMIS : acta pathologica, microbiologica, et immunologica Scandinavica》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Mona Aarenstrup Karlsen Claus Høgdall Lotte Nedergaard Kira Philipsen Prahm Nikoline Marie Schou Karlsen Anne Weng Ekmann‐Gade Tine Henrichsen Schnack Tim Svenstrup Poulsen Ib Jarle Christensen Estrid Høgdall 《APMIS : acta pathologica, microbiologica, et immunologica Scandinavica》2016,124(12):1038-1045
The aim of this study was to investigate the value of serum human epididymis protein 4 (HE4) and HE4 tissue protein expression to predict tumor resistance to adjuvant chemotherapy, progression‐free survival (PFS), and overall survival in patients with epithelial ovarian cancer (EOC). Consecutive inclusion of 198 patients diagnosed with EOC was conducted. Blood samples were collected prior to surgery and tissue samples during surgery. Patient data were registered prospectively in the Danish Gynecologic Cancer Database. The association between serum HE4 and HE4 tissue protein expression, resistance to adjuvant chemotherapy, PFS, and overall survival were analyzed in univariate analyses and in multivariate analyses adjusted for age, performance score, surgical outcome, stage, grade, and histological subtype. Serum HE4 levels predicted chemotherapy resistance, PFS, and overall survival correlated significantly (p < 0.001) in the univariate analyses; but after adjustment in a multivariate model, serum HE4 was insignificant, except in a subgroup analysis of postmenopausal women, where serum HE4 significantly predicted resistance to chemotherapy and progression‐free survival. HE4 tissue protein expression predicted PFS (p = 0.022) and overall survival (p = 0.047) in the univariate analysis, while HE4 tissue protein expression failed to predict these outcomes in the adjusted multivariate analyses. Serum HE4 or HE4 tissue protein expression are not independent factors of chemotherapy resistance or survival in patients with EOC, but serum HE4 might predict chemotherapy resistance and PFS in postmenopausal women. 相似文献
75.
76.
77.
78.
79.
There is growing evidence in the nephrology literature supporting the deleterious health effect of excess dietary phosphorus intake. This issue has largely escaped the attention of nutrition experts until this symposium, which raised the question of whether the same health concerns should be extended to the general population. The potential hazard of a high phosphorus intake in the healthy population is illustrated by findings from acute and epidemiologic studies. Acute studies in healthy young adults demonstrate that phosphorus intakes in excess of nutrient needs may significantly disrupt the hormonal regulation of phosphorus contributing to disordered mineral metabolism, vascular calcification, bone loss, and impaired kidney function. One of the hormonal factors acutely affected by dietary phosphorus loading is fibroblast growth factor-23, which may be a key factor responsible for many of the cardiovascular disease (CVD) complications of high phosphorus intake. Increasingly, large epidemiological studies suggest that mild elevations of serum phosphorus within the normal range are associated with CVD risk in healthy populations. Few population studies link high dietary phosphorus intake to mild changes in serum phosphorus due to study design issues specific to phosphorus and inaccurate nutrient composition databases. The increasing phosphorus intake due to the use of phosphorus-containing ingredients in processed food and the growing consumption of processed convenience and fast foods is an important factor that needs to be emphasized. 相似文献
80.
Ali Akbar Velayati Parissa Farnia Mohadese Mozafari Maryam Fatemeh Sheikholeslami Mona Afraei Karahrudi Payam Tabarsi Sven Hoffner 《The American journal of tropical medicine and hygiene》2014,90(1):99-105
We determined the prevalence of rifampin-monoresistant tuberculosis (RMR-TB) in Iran. Because development of RMR-TB is not common, we also identified the major risk factors associated with RMR-TB reported from different provinces of Iran. Data for 3,020 TB patients who remained or became smear positive after two, four, six, and nine months of standard first-line chemotherapy were retrospectively analyzed. Of 3,020 patients, 1,242 patients (41.1%) were culture and DNA positive for Mycobacterium tuberculosis. Of these patients, 73 (7.4%) patients had monoresistant isolates to rifampin, which was significantly higher than that for multidrug-resistant TB (5.8%). The average rate of RMR-TB in the studied population ranged from 5% to 10%. Classical investigation showed that 33.6% of patients had either a previous or family history of TB. Molecular epidemiology methods (i.e., spoligotyping and Mycobacterium intespersed repetitive unit–variable number tandem repeat), defined transmission link in three clusters (13%). These results outline the urgent need for a comprehensive plan for detection and treatment of RMR-TB cases. 相似文献