全文获取类型
收费全文 | 1479篇 |
免费 | 88篇 |
国内免费 | 9篇 |
专业分类
耳鼻咽喉 | 53篇 |
儿科学 | 68篇 |
妇产科学 | 18篇 |
基础医学 | 142篇 |
口腔科学 | 33篇 |
临床医学 | 84篇 |
内科学 | 371篇 |
皮肤病学 | 35篇 |
神经病学 | 50篇 |
特种医学 | 113篇 |
外科学 | 228篇 |
综合类 | 58篇 |
一般理论 | 5篇 |
预防医学 | 79篇 |
眼科学 | 30篇 |
药学 | 101篇 |
中国医学 | 2篇 |
肿瘤学 | 106篇 |
出版年
2022年 | 15篇 |
2021年 | 48篇 |
2020年 | 21篇 |
2019年 | 27篇 |
2018年 | 47篇 |
2017年 | 30篇 |
2016年 | 28篇 |
2015年 | 38篇 |
2014年 | 44篇 |
2013年 | 61篇 |
2012年 | 84篇 |
2011年 | 67篇 |
2010年 | 56篇 |
2009年 | 57篇 |
2008年 | 87篇 |
2007年 | 73篇 |
2006年 | 70篇 |
2005年 | 79篇 |
2004年 | 45篇 |
2003年 | 29篇 |
2002年 | 45篇 |
2001年 | 22篇 |
2000年 | 39篇 |
1999年 | 22篇 |
1998年 | 38篇 |
1997年 | 31篇 |
1996年 | 19篇 |
1995年 | 15篇 |
1994年 | 14篇 |
1993年 | 13篇 |
1992年 | 15篇 |
1991年 | 19篇 |
1990年 | 21篇 |
1989年 | 24篇 |
1988年 | 17篇 |
1987年 | 19篇 |
1986年 | 24篇 |
1985年 | 16篇 |
1984年 | 20篇 |
1983年 | 11篇 |
1981年 | 6篇 |
1980年 | 11篇 |
1979年 | 11篇 |
1978年 | 5篇 |
1977年 | 13篇 |
1976年 | 7篇 |
1975年 | 10篇 |
1973年 | 9篇 |
1972年 | 6篇 |
1971年 | 10篇 |
排序方式: 共有1576条查询结果,搜索用时 46 毫秒
51.
Ethnic variation in certain hematological and biochemical reference intervals in a south Indian healthy adult population 总被引:1,自引:0,他引:1
Sundaram M Mohanakrishnan J Murugavel KG Shankar EM Solomon S Srinivas CN Solomon SS Pulimi S Piwowar-Manning E Dawson S Livant E Kumarasamy N Balakrishnan P 《European Journal of Internal Medicine》2008,19(1):46-50
BACKGROUND: We established the biochemical and hematological reference intervals among a south Indian healthy adult population attending an HIV referral centre in Chennai, southern India. METHODS: In a cross sectional study, 213 study subjects (129 male and 84 female) were studied between March and August 2005. All of the parameters were analyzed using standard hematological and biochemical techniques. RESULTS: Certain biochemical (viz. total bilirubin, alanine transaminase, albumin, creatinine, total protein, lipid profile, creatine phosphokinase, uric acid and lactate) and hematological (mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration and lymphocyte levels) parameters presented higher upper limits. In addition, the upper limits of white blood cell count, platelet count, hematocrit, red blood cell count and hemoglobin level were low in comparison to the currently reported ranges. CONCLUSION: Ethnic variation in reference intervals was observed in certain biochemical and hematological analytes in a south Indian adult population. 相似文献
52.
Anu Balakrishnan Rohit Aggarwal Vikas Agarwal Latika Gupta 《International journal of rheumatic diseases》2020,23(9):1126-1135
Inclusion body myositis is a rare sporadic inflammatory‐degenerative myopathy of the elderly. Despite being the commonest type of acquired myopathy after the age of 50, misdiagnosis is extremely common. The most frequent hurdle in identifying new cases is the wrong diagnosis of polymyositis or motor neuron disease. Novel insights into pathogenic mechanisms have heralded the quest for newer therapeutics as well as drug repurposing in this otherwise progressive disorder. 相似文献
53.
There is paucity of literature on the relation of obesity with recurrent and chronic pancreatitis. We recorded the clinical details and the outcome of five patients with recurrent pancreatitis who had components of the metabolic syndrome. Their age ranged from 8 to 20 years. All five patients had acanthosis nigricans. Body mass index (BMI) could not be evaluated as these patients lost weight following episodes of pancreatitis. Three patients had two or more first-degree relatives who had diabetes mellitus. Only one patient had severe necrotizing pancreatitis. Coexisting liver disease was seen in two patients. Elevated serum cholesterol levels and moderately elevated serum triglycerides along with elevated serum amylase levels observed in these patients suggest possibility of a different mechanism from that of hypertriglyceridemia-related pancreatitis. Evaluation of pancreatic steatosis should be considered in patients with pancreatitis in the setting of metabolic syndrome. 相似文献
54.
55.
56.
Michael S. Cartwright MD Samantha Demar BS Leah P. Griffin MS Nikhil Balakrishnan MD Jessica M. Harris AAS Francis O. Walker MD 《Muscle & nerve》2013,47(4):515-521
Introduction: Nerve and muscle ultrasound has been studied in several conditions, but validity and reliability have not been assessed systematically. Methods: Nerve cross‐sectional area and muscle thickness were measured ultrasonographically at several sites in 4 cadavers, which were then dissected, and actual measurements were obtained. To assess intrarater and interrater reliability, between 3 and 5 ultrasonographers, with varying experience levels, made repeated measurements on healthy volunteers. Results: Correlation coefficients for nerve and muscle validity were >0.968 (P < 0.001), and for intrarater reliability were >0.901 (P < 0.001) for still and real‐time images. Correlation coefficients for interrater reliability were more varied, but for still images they were all significant at the P < 0.001 (0.542–0.998) level, and for real‐time images they were significant at the P < 0.05 level for half the sites (0.243–0.981). Conclusion: Overall, nerve and muscle ultrasound is a valid and reliable diagnostic imaging technique. Muscle Nerve, 2013 相似文献
57.
Susceptible and protective associations of HLA DRB1*/DQB1* alleles and haplotypes with ischaemic stroke 下载免费PDF全文
V. Murali C. Rathika S. Ramgopal R. Padma Malini M. J. Arun Kumar V. Neethi Arasu K. Jeyaram Illiayaraja K. Balakrishnan 《International journal of immunogenetics》2016,43(3):159-165
Stroke has emerged as the second commonest cause of mortality worldwide and is a major public health problem. For the first time, we present here the association of human leucocyte antigen (HLA)‐DRB1*/DQB1* alleles and haplotypes with ischaemic stroke in South Indian patients. Ischaemic stroke (IS) cases and controls were genotyped for HLA‐DRB1*/DQB1* alleles by polymerase chain reaction sequence‐specific primers (PCR‐SSP) method. The frequencies of HLA class II alleles such as DRB1*04, DRB1*07, DRB1*11, DRB1*12, DRB1*13, DQB1*02 and DQB1*07 were high in IS patients than in the age‐ and gender‐matched controls, suggesting that the individuals with these alleles are susceptible to ischaemic stroke in South India. The frequencies of alleles such as DRB1*03, DRB1*10, DRB1*14, DQB1*04 and DQB1*05 were less in IS cases than in the controls, suggesting a protective association. Haplotypes DRB1*04‐DQB1*0301, DRB1*07‐DQB1*02, DRB1*07‐DQB1*0301, DRB1*11‐DQB1*0301 and DRB1*13‐DQB1*06 were found to be high in IS patients conferring susceptibility. The frequency of haplotype DRB1*10‐DQB1*05 was high in controls conferring protection. IS‐LVD and gender‐stratified analysis too confirmed these susceptible and protective associations. Thus, HLA‐DRB1*/DQB1* alleles and haplotypes strongly predispose South Indian population to ischaemic stroke. Further studies in different populations with large sample size or the meta‐analysis are needed to explain the exact mechanism of associations of HLA gene(s) with IS. 相似文献
58.
59.
Ganesh-Babu B Subburaman John H Kempen Saravanan Durairaj Vijayakumar Balakrishnan Vijayakumar Valaguru Venkatesh Prajna Namperumalsamy Ravilla Duraisamy Thulasiraj Sachin Gupta 《Indian journal of ophthalmology》2020,68(10):2094
Purpose:To identify factors affecting family members'' decision whether to donate eye organs.Methods:A community-based case-control study based on in-home interviews with families of deceased individuals who had or had not donated eye organs, in Madurai district, Tamil Nadu, India. Data collected were knowledge and awareness of eye donations, whether the deceased individual had expressed or pledged willingness to donate, and family members'' attitudes and willingness to donate their own eye organs.Results:Seventy-six families of donors and 256 families of non-donors completed the survey. Multivariable analysis showed that the following variables were significantly associated with a donation: age, whether the deceased had registered for eye donation, pre-expressed willingness of deceased to donate, whether family members personally know beneficiaries of eye donations, and higher score on a scale evaluating knowledge and awareness about eye donation. The majority of donors'' families (71%) had been encouraged by someone to donate. Among non-donor families, a substantially larger fraction (52.8%) indicated they would have donated had someone reminded or encouraged them to do so, in comparison with those who indicated lack of awareness or knowledge (14.5%).Conclusion:Community programs are likely to be effective if they encourage individuals to pledge their eyes or express their willingness to donate their eyes to family members in advance of death; they increase public awareness of the value of eye donation. A friend, family member, neighbor or counselor approaching bereaved families and having a dialogue about eye donation would substantially increase the probability of a decision to donate. 相似文献
60.
Human red cells (RBCs) were collected in CPDA-1 and then freeze-dried in lyoprotective solution. The lyophilized RBCs were then stored at -20 degrees C for 7 days. At the end of the storage period, the lyophilized RBCs were rehydrated and washed in dextrose saline. The washed, reconstituted, lyophilized RBCs were resuspended in final wash solutions of ADSOL, CPDA-1, or a special additive solution containing glucose, citrate, phosphate, adenine, and mannitol, and then they were stored at 4 degrees C for an additional 7 days. The main purpose of this study was to determine whether human RBCs can be lyophilized in such a manner that normal metabolic, rheologic, and cellular properties are maintained during rehydration and subsequent storage in standard blood bank preservative solutions. Our results show that reconstituted, lyophilized RBCs maintained levels of ATP, 2,3 DPG, lactate, and cellular properties that are equal to or better than those in control nonlyophilized RBCs stored for a comparable period in CPDA-1. Reconstituted, lyophilized RBCs stored at 4 degrees C after rehydration also show better maintenance of ATP, 2,3 DPG, and lactate than do control RBCs stored in the same preservative solutions for comparable periods. 相似文献