海绵窦海绵状血管瘤的诊断及显微手术治疗

目的 探讨海绵窦海绵状血管瘤的临床诊断及显微于术方法.方法 回顾分析12例海绵窦海绵状血管瘤病人的临床资料,对相关文献进行复习.结果 12例患者均行显微外科手术治疗,8例经颧弓翼点入路,2例经颅眶颧入路,2例经翼点人路,从中颅底硬膜下暴露并切除病变.肿瘤拿切除5例,次全切除4例,部分切除3例,无手术死亡病例.术后视力进步者2例,4例有动眼神经麻痹,6例有面部麻木.结论 自中颅底硬膜下暴露并切除肿瘤是一种有效的全切肿瘤的方法.经硬膜下入路,切开海绵窦外侧壁可以近距离达到供血动脉,更有效地减少出血.     

病原菌耐药性检测结果在下呼吸道感染治疗中价值的评价

目的 评价病原菌耐药性检测结果在下呼吸道感染治疗中的价值.方法 统计下呼吸道感染住院患者痰标本的培养结果,了解病原菌菌种分布及其耐药状况;回顾调查近期该类患者的临床资料及培养送检率、阳性率、抗菌药物使用情况.结果 下呼吸道感染住院患者痰液培养的送检率为67.8%,病原菌阳性率为55.9%;菌种分布以革兰阴性菌为主,占82.39%,革兰阳性菌占14.18%;不同病原菌对常用抗菌药物呈现不同程度的耐药,肠杆菌科细菌、非发酵菌对氟喹诺酮类抗菌药物环丙沙星的耐药率分别为47.8%、34.8%,对哌拉西林/他唑巴坦的耐药率分别为31.5%、44.7%;金黄色葡萄球菌对氟喹诺酮类抗菌药物左氧氟沙星的耐药率为63.9%.结论 下呼吸道感染病原菌对常用抗菌药物耐药率较高,临床治疗仍以经验用药为主,对下呼吸道感染治疗中抗菌药物选择的作用不明显.     

健康青年定量平衡分析及其影响因素

目的 对健康青年进行平衡功能定量测试,获得静态/动态姿势图参数的正常值范围,探讨受试者个体因素对参数的影响.方法 利用Synapsys(SPS)静动态平衡仪对50名健康青年进行稳定极限试验、睁眼/闭眼静态平衡试验、睁眼/闭眼前后向动态平衡试验、睁眼/闭眼左右向动态平衡试验.结果 得到了健康青年静态/动态姿势图各参数、稳定极限范围、Romberg商数、感觉结构组成等参数的95%参考值范围;受试者身高、体重差异对一些平衡测试参数有一定影响,特别是与极限稳定范围呈高度正相关;性别差异会影响稳定极限范围、动态平衡参数、感觉结构组成等测试结果.结论 静动态平衡仪测试可定量评测人体平衡功能,临床中应根据不同个体特征参照正常值范围.     

Radionuclide Angiocardiography in Post-myocardial Infarction Patients

ABSTRACT One hundred and one representative post-myocardial infarction (MI) patients were investigated with radionuclide angiocardiography (RNA) and exercise test within 1 month of the MI and after 6 and 12 months. From the RNA were calculated the left ventricular ejection fraction (LVEF) and a quantified phase image, the phase standard deviation (phase-SD), representing the timing of the left ventricular contraction. The mean phase-SD was significantly higher among these patients (18°, 19° and 18°, respectively, at the three investigations) compared to phase-SD in normals (6°), indicating an impaired timing of the left ventricular (LV) contraction. At all three investigations a significant correlation was found between the phase-SD and the LVEF (r=0.58, r=-0.74 and r=-0.75, respectively) and the corrected QT interval (r=0.27, r=0.44 and r=0.39, respectively). Maximal serum ASAT in patients with their first MI correlated significantly to phase-SD. Low exercise capacity or unfavourable NYHA classification was associated with high phase-SD. Phase-SD higher than mean was also associated with significantly increased mortality during the follow-up year (P=0.0057). In conclusion, phase-SD, reflecting the timing of the LV contraction wave, is easily accessible and clinically relevant. It merits further investigation as a prognostic factor after an MI.     

Staging of Idiopathic Myelofibrosis: Significance of Haemoglobin Value and Reticulocyte Count

ABSTRACT. A retrospective analysis of 18 patients with idiopathic myelofibrosis (IMF) suggested that IMF is adequately staged by combining haemoglobin value and reticulocyte count. Four stages were recognized. All deaths occurred in late stage. The stages appeared to reflect a sequential course of the disease. The present staging system adequately identified patients at high risk. However, the rate of disease progress varied greatly. It is therefore suggested that the rate of disease progress should also be considered when an individual patient is evaluated.     

Capillary permeability in healthy males with different insulin response to glucose

The capillary permeability in human skeletal muscle, expressed as capillary diffusion capacity (CDC) for 51Cr-EDTA, was determined during exercise with a local clearance method in two groups of healthy male subjects: a younger group with a mean age of 30 years and an older one with a mean age of 58 years. The main finding was that, in both age groups, CDC was significantly negatively correlated to the early phase of insulin response to an intravenous glucose load. No correlation was found between CDC and peripheral insulin sensitivity. CDC was significantly higher in the older age group (P less than 0.01) independent of insulin response, blood flow and body weight. These data indicate that subjects with low insulin response to glucose have a higher capillary permeability than high responders, and that muscle capillary permeability increases with age.     

Oral recognition of forms and oral muscular coordination ability. A longitudinal study in young adults

A study has been carried out to investigate the constancy of results in oral recognition of forms (RF-test) and in tests which demand a fine coordination of the oral muscular apparatus (MA-test). Twenty examinees with a mean age of 22.5 years were tested with both test forms in 1972 and retested 4 years later in 1976. The performances in the RF- as well as in the MA-test improved considerably. As to the learning (training) effect in both test forms, the test results acquired by training during the previous period have largely been preserved until the next test period 4 years later. Individuals with a given capacity to perform either the RF- or MA-test, showed about the same grade of ability 4 years later. The RF- as well as the MA-test seem to reflect a given ability, which, at least in this age-group, remained constant during a period of 4 years. These results may be explained by reference to the notion of schema in which some motor-sensory feed-back will be stored. The specificity of the perceptual and motor patterns used, may have produced schemata with good resistance against forgetting.