全文获取类型
收费全文 | 11983篇 |
免费 | 1393篇 |
国内免费 | 57篇 |
专业分类
耳鼻咽喉 | 166篇 |
儿科学 | 394篇 |
妇产科学 | 308篇 |
基础医学 | 1382篇 |
口腔科学 | 903篇 |
临床医学 | 1083篇 |
内科学 | 2764篇 |
皮肤病学 | 434篇 |
神经病学 | 714篇 |
特种医学 | 382篇 |
外国民族医学 | 3篇 |
外科学 | 2007篇 |
综合类 | 252篇 |
一般理论 | 4篇 |
预防医学 | 663篇 |
眼科学 | 290篇 |
药学 | 790篇 |
中国医学 | 53篇 |
肿瘤学 | 841篇 |
出版年
2024年 | 9篇 |
2023年 | 126篇 |
2022年 | 344篇 |
2021年 | 613篇 |
2020年 | 409篇 |
2019年 | 637篇 |
2018年 | 723篇 |
2017年 | 548篇 |
2016年 | 593篇 |
2015年 | 520篇 |
2014年 | 677篇 |
2013年 | 884篇 |
2012年 | 849篇 |
2011年 | 966篇 |
2010年 | 615篇 |
2009年 | 450篇 |
2008年 | 564篇 |
2007年 | 557篇 |
2006年 | 477篇 |
2005年 | 494篇 |
2004年 | 436篇 |
2003年 | 363篇 |
2002年 | 323篇 |
2001年 | 174篇 |
2000年 | 154篇 |
1999年 | 130篇 |
1998年 | 69篇 |
1997年 | 52篇 |
1996年 | 59篇 |
1995年 | 45篇 |
1994年 | 29篇 |
1993年 | 30篇 |
1992年 | 40篇 |
1991年 | 24篇 |
1990年 | 27篇 |
1989年 | 33篇 |
1988年 | 45篇 |
1987年 | 54篇 |
1986年 | 42篇 |
1985年 | 37篇 |
1984年 | 32篇 |
1983年 | 19篇 |
1982年 | 13篇 |
1981年 | 17篇 |
1979年 | 13篇 |
1978年 | 7篇 |
1977年 | 12篇 |
1975年 | 10篇 |
1969年 | 7篇 |
1966年 | 8篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
71.
Mostafa Abdelkhalek Ayman M. Ali Mohamed Abdelwahab 《European journal of orthopaedic surgery & traumatology : orthopedie traumatologie》2013,23(4):443-448
Aim
The purpose of this study is to evaluate the clinical and radiological outcomes of cemented bipolar arthroplasty as a primary treatment for unstable intertrochanteric fracture in the elderly patients.Methods
Twenty hips with unstable intertrochanteric fractures were followed for more than 2 years after cemented bipolar hemiarthroplasty. The mean age was 69 years, and the mean follow-up period was 30.5 months. We evaluated the results by Harris hip score, complications, and radiologic findings.Results
At the last follow-up, the mean Harris hip score was 83.3 points. Radiologically, there was no case of osteolysis. All stems were stable without significant changes in alignment or progressive subsidence.Conclusions
Bipolar hemiarthroplasty with calcar reconstruction is a good option for unstable intertrochanteric fractures in elderly patients with severe osteoporosis with strict indication selection. Longer-term studies with larger numbers of patients are required to address the issues of late complications. 相似文献72.
Relationship between peripheral and central venous pressures in different patient positions, catheter sizes, and insertion sites 总被引:2,自引:0,他引:2
Tugrul M Camci E Pembeci K Al-Darsani A Telci L 《Journal of cardiothoracic and vascular anesthesia》2004,18(4):446-450
OBJECTIVE: To investigate the relationship between peripheral and central venous pressures in different patient positions (supine, prone, lithotomy, Trendelenburg, and Fowler), different catheter diameters (18 G and 20 G), and catheterization sites (dorsal hand and forearm) during surgical procedures. DESIGN: Prospective clinical study. SETTINGS: University hospital. PARTICIPANTS: Five hundred adult patients. INTERVENTIONS: Peripheral over-the-needle intravenous catheters were placed in the dorsal hand or forearm. Central venous catheters were inserted via the internal jugular or subclavian vein after induction of anesthesia. MEASUREMENTS and MAIN RESULTS: Simultaneous measurements of central and peripheral venous pressures were made during stable conditions at random time points in surgery; 1953 paired measurements were performed. Mean central venous pressure was 11 +/- 3.7 mmHg and peripheral venous pressure was 13 +/- 4 mmHg (p = 0.0001). The overall correlation between central venous and peripheral venous pressures was found to be statistically significant (r = 0.89, r(2) = 0.8, p = 0.0001). Mean difference between peripheral and central venous pressure was 2 +/- 1.8 mmHg. Ninety-five percent limits of agreement were 5.6 to -1.6 mmHg. CONCLUSION: It has been assumed that replacing central venous pressure by peripheral venous pressure would cause problems in clinical interpretation. If the validity of this data is confirmed by further studies, the authors suggest that central venous pressure could be estimated by using regression equations to compare the 2 methods. 相似文献
73.
Perigaud C Baron O Roussel JC Al Habash O Despins P Michaud JL Duveau D 《The Annals of thoracic surgery》2004,78(2):707-709
Postpneumonectomy syndrome is defined as an airway obstruction due to mediastinal shift and rotation after pneumonectomy. A patient who had undergone a left pneumonectomy for bronchial carcinoma 13 years before presented with tension pneumothorax of her remaining lung. Although all factors relevant to the development of postpneumonectomy syndrome were ascertained, the patient had a pneumothorax rather than an airway obstruction. This pneumothorax was treated surgically. The goal of this operation was to reduce the right pleural cavity volume by implanting an intrapleural prosthesis in the pneumonectomy cavity. This treatment is identical to that used for postpneumonectomy syndrome, which allows the right lung to be rejoined with the thoracic wall. 相似文献
74.
The urofacial syndrome is characterized by functional obstructive uropathy associated with an inverted smile. The importance of the subject is that it sheds light, not only on the muscles of facial expression, but also on the inheritance of voiding disorders and lower urinary tract malformations. We report a 10-year-old-male patient who had the urofacial syndrome. Early diagnosis of the urofacial syndrome is important to avoid upper urinary tract damage and renal failure. 相似文献
75.
Kniemeyer HW Voshege M Soliman A Abu Al Nasr TM Beckmann H Edelmann M 《The Journal of cardiovascular surgery》2012,53(2):241-246
Spontaneous recanalization of the internal carotid artery (ICA) is rarely observed. Mainly case reports are published. Most often early recanalization occurs within days or weeks and only a few cases of late recanalization months or years after detected occlusion are reported. Symptomatic bilateral ICA occlusion is regarded as an acceptable indication for extra-intracranial (EC-IC) bypass. The authors report on a case with bilateral symptomatic ICA occlusion and EC-IC bypass >2 years prior to detected spontaneous leftsided recanalization. Spontaneous recanalization unmasking a high degree ICA stenosis at the carotid bifurcation allowed a successful subsequent surgical recanalization in this patients. Mechanisms of early and late recanalization as well as treatment options are discussed. 相似文献
76.
Ayman El-Sayed Khalil Mostafa Ahmed Ayoub 《Journal of orthopaedics and traumatology》2012,13(4):179-188
Background
Multiplanar complex C3-type unstable distal femoral fractures present many challenges in terms of approach and fixation. This prospective study investigates a possible solution to these problems through double plating with autogenous bone grafting via a modified Olerud extensile approach.Materials and methods
Twelve patients with closed C3-type injuries were included; eight of them were male, and their mean age was 33.5 years (range 22–44 years). Mechanism of injury was road traffic accident (RTA) in nine patients and fall from height in the other three cases. Eight cases were operated during the first week and four cases during the second week after injury. Mean follow-up was 13.7 months (range 11–18 months).Results
Mean radiological healing time was 18.3 weeks (range 12-28 weeks), and all cases had good radiological healing without recorded nonunion or malunion. Clinically, two cases (16.7 %) had excellent results, five cases (41.7 %) had good results, three cases (25 %) had fair results, and two cases (16.7 %) had poor results. No cases developed skin necrosis, deep infection, bone collapse, or implant failure. However, two cases (16.7 %) had limited knee flexion to 90° and required subsequent quadricepsplasty.Conclusions
Use of this modified highly invasive approach facilitated anatomical reconstruction of C3-type complex distal femoral fractures with lower expected complication rate and acceptable clinical outcome, especially offering good reconstruction of the suprapatellar pouch area. It can be considered as a standby solution for managing these difficult injuries. 相似文献77.
Alaa Magdy Ayman El Nakeeb El Yamani Fouda Mohamed Youssef Mohamed Farid 《Journal of gastrointestinal surgery》2012,16(10):1955-1962
Background
Lateral internal sphincterotomy has been proven highly effective in curing anal fissure but with a high incidence of postoperative incontinence.Objective
We compared conventional lateral internal sphincterotomy, V-Y advancement flap, and combined tailored lateral internal sphincterotomy with V-Y advancement flap in treating anal fissure.Patients
Consecutive patients treated for anal fissure at our colorectal unit were evaluated for inclusion. Participants were randomly allocated to receive conventional sphincterotomy (GI), V-Y advancement flap (GII), or combined tailored lateral sphincterotomy with V-Y advancement l flap (GIII).Main Outcome Measures
The primary outcome measure was the incontinence rate; secondary outcomes included healing rate, operative time, anal manometery, and recurrence rate.Results
One hundred fifty patients with chronic anal fissure were randomized. Healing rate after 1?year was 84?% in GI, 48?% in GII, and 94?% in GIII, respectively (P?=?0.001). The recurrence rate was 4?% in G1, 22?% in GII, and 2?% in GIII (P?=?0.01). Incontinence rate was 14?% in GI, 0?% in GII, and 2?% in GIII (P?=?0.03).Conclusion
Although all three procedures are simple and easy to perform, tailored lateral internal sphincterotomy with V-YF appears to produce the greatest healing rate, with the fewest complications and less rate of recurrence. 相似文献78.
Antonio Ríos Zambudio Ana López-Navas Marcos Ayala-García María José Sebastián Anselmo Abdo-Cuza Jeannina Alán Laura Martínez-Alarcón Ector Jaime Ramírez Gerardo Muñoz Gerardo Palacios Juliette Suárez-López Roberto Castellanos Beatriz González Miguel Angel Martínez Ernesto Díaz Pablo Ramírez Pascual Parrilla 《The Journal of heart and lung transplantation》2012,31(8):850-857
79.
V. A. Lobanov A. A. Gajadhar B. Al‐Adhami H. M. Schwantje 《Transboundary and Emerging Diseases》2012,59(3):233-243
Twenty‐three free‐ranging white‐tailed deer (WTD; Odocoileus virginianus) and six mule deer (MD; Odocoileus hemionus) from south‐central British Columbia, Canada, were tested for Anaplasma marginale by msp5 gene‐specific PCR and Ehrlichia spp. by 16S rRNA or citrate synthase (gltA) gene‐specific PCR, as well as by PCR with universal 16S rRNA primers detecting a wide range of bacteria. No deer tested positive for A. marginale. Amplification with universal 16S rRNA primers followed by sequencing of cloned fragments detected an Anaplasma sp. in one of 23 (4.3%) WTD and six of six (100%) MD and Bartonella sp. in four of 23 (17.4%) WTD. The Anaplasma sp. was genetically distinct from A. marginale and all other recognized members of the genus. Four of six (66.7%) MD and 0 of 23 (0%) WTD were Ehrlichia positive by PCR with primers for 16S rRNA and gltA genes. The sequences of gltA PCR fragments were identical to each other and to the respective region of the gltA gene of an Ehrlichia sp. which we detected previously in naturally infected cattle from the same area, suggesting the possibility of biological transmission of this rickettsia between cattle and wild cervids. Antibodies reactive with the MSP5 protein of A. marginale were detected using a competitive enzyme‐linked immunosorbent assay in two of six (33.3%) MD, but not in WTD. The two seropositive MD were PCR positive for both the Anaplasma sp. and Ehrlichia sp. detected in this study, suggesting a reaction of antibodies against one or both of these rickettsias with the MSP5 antigen. 相似文献
80.
Khaled Sirajedine Rida Fardous Mohamad Al Adib Henry Colomb Audrey Maurin 《Néphrologie & thérapeutique》2012,8(4):226-230
IntroductionGeriatric Nutritional Risk Index (GNRI) is a simple and quantitative method (based on three objective measurements: weight, height, albumin) for screening patients at risk for malnutrition. However no data are available regarding its relation with mortality in Caucasian hemodialysis patients. We tested the predictive value of GNRI on mortality in a hemodialysis population followed up prospectively for 18 months.MethodsA total of 46 stable prevalent (mean age: 76 ± 11 years, range: 42–95) hemodialysis patients from one center were included in the study. GNRI with other nutritional parameters were evaluated for all patients.ResultsSixteen patients (35%) died during the 18 months of follow-up. Multiple logistic model showed that GNRI and Charlson co-morbidity score were significant predictors of mortality. Age and gender were not significant.ConclusionOur preliminary study carried out on a series of prevalent hemodialysis patients suggests that GNRI is predictor of mortality. To recommend the use of this index for the screening of hemodialysis patients with malnutrition at risk of mortality, our results should be confirmed by a large cohort study. 相似文献