"Lysostrip" experiments with HLA class-II antigens. I. Independent surface mobility of DQ and DR molecules

We report on results of lysostrip experiments designated to analyse the molecular relations between DQ and DR antigens. The purpose of lysostrip application was to determine whether these antigens can independently be redistributed on B-cell surface by incubation with a specific antibody followed by incubation with F(ab')2 fragments of rabbit antihuman Ig. The obtained results have clearly shown that DQ antigens, and supertypic and narrow DR antigens, move independently, indicating that they are located on separate molecules, supporting the concept of different DQ and DR loci.     

Behavioral neurology of multi-infarct dementia

Multi-infarct dementia (MID) is a heterogeneous entity in which a variety of cerebrovascular disorders leads to intellectual impairment. A variety of patterns of behavioral changes may be observed in MID, depression, psychosis, and personality change are common. The neurobehavioral syndromes of MID are determined by the specific arteries involved and the location and extent of tissue infarction.     

Chronic hiccups

Patients with chronic hiccups should be carefully examined for an underlying disorder while receiving symptomatic treatment. Treatment includes physical maneuvers, drugs such as chlorpromazine, metoclopramide, anticonvulsants or quinidine, and other, less tested modalities such as hypnosis. Only those patients with disabling hiccups that do not respond to conservative treatment should be considered for phrenic nerve surgery.