Alverine induced toxic hepatitis: a case report.

Drug-induced hepatotoxicity is an important cause of hepatocellular injury. Hepatic necrosis may range from asymptomatic elevations in transaminases to fulminant hepatic failure and death. Alverine is an antispasmodic drug which is especially used in patients with irritable bowel syndrome. Only a few cases of alverine associated hepatotoxicity have been reported previously. We present the case of a patient with alverine induced hepatotoxicity and cholestasis, which has only seldomly been reported in the literature.     

Nonsurgically treated cervical brucellar epidural abscess causing spinal cord compression

Cervical spinal cord compression due to brucellar epidural abscess is extremely rare, with only 13 previously reported cases. We present another case of cervical spinal epidural abscess causing spinal cord compression. Diagnostic tools and treatment options are discussed.     

Common complications of segmental bone transport with Ilizarov technique in defective tibia pseudoarthrosis: a review

In tibial pseudoarthrosis, segmental bone transport with Ilizarov external fixator is being widely applicated all around the world, with encouraging successful outcomes. As the treatment with this technique requires a long period of time, the surgeon may face many problems which may negatively affect the final outcome. Pin tract infection, early or delayed consolidation, axial deviation and translation at the target area, skin inversion, rupture of the bone by the wires and joint contractures or stiffness form the main and common clinical problems. The rate of failure and complications with Ilizarov method used for diaphysial bone defects are so rare when precise technical details are carried out. With other treatment modalities, it is usually too difficult to obtain union synchronously with infection eradication. Thus, the Ilizarov technique presents successful outcomes against some complications mentioned above. Segmental bone transport is a surgical technique in which some of the problems can never be prevented. However, close patient follow up and always keeping the problems in mind make early diagnosis possible. With the early recognition of problems, successful treatment and increased overall outcome can be expected.     

Synthesis and polymerization of 2- and 3-substituted thiophene derivatives linked by polyether bridges

New compounds consisting of 2- and 3-thienyl units linked by polyether bridges have been synthesized and their electrochemical polymerization was performed via constant potential electrolysis (CPE) in an electrolytic solution containing 0.1 M tetrabutylammonium hexafluorophosphate (TBAPF₆) dissolved in CH₃CN. 2-Thienyl monomers (I and II), but not 3-thienyl monomers (III and IV), were also polymerized via chemical oxidation, which yielded broken π-conjugated polymer products. The polymers were characterized using ¹H NMR and FT-IR spectroscopic techniques. It was found that both chemical and electrochemical oxidation of 2-thienyl monomers gave mainly poly(2,2′-bithiophenemethylene) due to elimination of polyether chains during the polymerization reaction. On the other hand, electrochemical oxidation of 3-thienyl monomers resulted in corresponding polymers without any cleavage of polyether bridges. Spectroelectrochemical (SPEL) properties of the products were investigated using UV–Vis spectroscopic techniques.     

Radiology of an atypical fibro-osseous lesion confined to the nasal cavity

Fibro-osseous lesions of the sinonasal region are relatively frequent, but those strictly confined to the nasal cavity are rare. We report an atypical fibro-osseous lesion in the nasal cavity and describe its radiological features. The differential diagnosis is discussed. Received: 18 November 1997 Accepted: 6 April 1998     

Clinical presentation of a sphenochoanal polyp

Although choanal polyps frequently arise from the maxillary sinus, a choanal polyp originating from the sphenoid sinus is a rare entity. In this report, an unusual case of a large choanal polyp taking origin from the sphenoid sinus is presented. The reasons for its development and methods of management are discussed. Received: 1 August 1996 / Accepted: 20 January 1997     

Approach to benign tumors of the palate: analysis of 28 cases

We conducted a retrospective analysis of 28 patients-15 men and 13 women, aged 17 to 71 years (mean: 41.6)-who had undergone surgery for the treatment of a benign tumor of the hard or soft palate. The most common chief complaint was a palatal mass, which was reported by 14 patients (50.0%). Tumors were more common in the hard palate than in the soft palate by a margin of 23 to 5 (82.1 to 17.9%; p = 0.001). The most common histopathologic diagnosis was pleomorphic adenoma, which occurred in 9 cases (32.1%). Most patients were treated with local excision with clear margins, which was sufficient in almost all cases, as there were only 2 recurrences, both of which occurred in men with a hard-palate pleomorphic adenoma. For these 2 patients, a wider excision and repair with palatal islet flaps was performed, and no further recurrence or malignant transformation was observed during follow-up. Two patients with a soft-palate hemangioma were treated with an intralesional steroid injection and radiofrequency ablation, which reduced the size of their lesion considerably.