全文获取类型
收费全文 | 1925篇 |
免费 | 79篇 |
国内免费 | 13篇 |
专业分类
耳鼻咽喉 | 69篇 |
儿科学 | 99篇 |
妇产科学 | 36篇 |
基础医学 | 99篇 |
口腔科学 | 189篇 |
临床医学 | 169篇 |
内科学 | 384篇 |
皮肤病学 | 30篇 |
神经病学 | 109篇 |
特种医学 | 82篇 |
外科学 | 441篇 |
综合类 | 15篇 |
一般理论 | 1篇 |
预防医学 | 28篇 |
眼科学 | 86篇 |
药学 | 100篇 |
中国医学 | 2篇 |
肿瘤学 | 78篇 |
出版年
2024年 | 1篇 |
2023年 | 9篇 |
2022年 | 15篇 |
2021年 | 39篇 |
2020年 | 22篇 |
2019年 | 29篇 |
2018年 | 46篇 |
2017年 | 34篇 |
2016年 | 38篇 |
2015年 | 51篇 |
2014年 | 87篇 |
2013年 | 89篇 |
2012年 | 125篇 |
2011年 | 118篇 |
2010年 | 82篇 |
2009年 | 71篇 |
2008年 | 141篇 |
2007年 | 186篇 |
2006年 | 165篇 |
2005年 | 168篇 |
2004年 | 144篇 |
2003年 | 96篇 |
2002年 | 103篇 |
2001年 | 35篇 |
2000年 | 36篇 |
1999年 | 18篇 |
1998年 | 14篇 |
1997年 | 8篇 |
1996年 | 8篇 |
1995年 | 10篇 |
1994年 | 1篇 |
1993年 | 5篇 |
1992年 | 3篇 |
1991年 | 2篇 |
1990年 | 1篇 |
1989年 | 3篇 |
1988年 | 2篇 |
1987年 | 2篇 |
1986年 | 1篇 |
1984年 | 1篇 |
1983年 | 1篇 |
1982年 | 2篇 |
1976年 | 1篇 |
1975年 | 1篇 |
1970年 | 1篇 |
1966年 | 1篇 |
1965年 | 1篇 |
排序方式: 共有2017条查询结果,搜索用时 31 毫秒
31.
32.
33.
A 41-year-old female patient presented with a well-known long history of diabetes mellitus type 1 with diabetic nephropathy, dysuria, left-sided flank pain, nausea and vomiting. The patient was previously treated with ciprofloxacin for the same symptoms but after improvement of symptoms was discharged of her own volition. This case underlines that even young people in need of dialysis are endangered by infections due to uremic immune dysfunction. 相似文献
34.
Acute anterior myocardial infarction due to aortosaphenous vein graft occlusion with very large thrombus burden
下载免费PDF全文
![点击此处可从《Experimental & Clinical Cardiology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Atilla Bitigen Emre Gurel Ali Cevat Tanalp Soe Moe Aung Yelda Baaran 《Experimental & Clinical Cardiology》2007,12(4):203-205
A 75-year-old man, with a previous history of myocardial infarction and three-vessel coronary artery bypass grafting, presented with an acute anterior ST-elevation myocardial infarction. The vein graft to the left anterior descending artery was occluded with heavy thrombus burden, and the other grafts were patent. After administering a bolus dose of tirofiban and then undergoing percutaneous coronary intervention without stenting to the left anterior descending artery saphenous vein graft, intracoronary thrombolytic infusion was performed to maintain the patency of the vein graft. The patient was asymptomatic after medical follow-up. This may be an effective treatment option in patients with large thrombus burden and requires further investigation through large-scale trials. 相似文献
35.
36.
37.
Zehra Narli Ozdemir Guldane Cengiz Seval Ugur Sahin Atilla Uslu Mehmet Gunduz Sinem Civriz Bozdag Selami Kocak Toprak Meltem Kurt Yuksel Pervin Topcuoglu Isinsu Kuzu Muhit Ozcan Gunhan Gurman Osman Ilhan 《Indian journal of hematology & blood transfusion》2021,37(1):67
PurposeBlastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and poor prognostic hematological malignancy. There is still no standard treatment established for BPDCN patients. We aim to summarize the main clinical, biological features and treatment of 9 BPDCN patients.MethodsNine patients with BPDCN who had been diagnosed between July 2008 and December 2018 in Ankara University School of Medicine, were retrospectively evaluated.ResultsAll patients (n = 9) were male, median age was 64 (21–80). Five patients (55.6%) had bone marrow infiltration, 5 patients (55.6%) cutaneous lesions, 6 patients (66.7%) lymph node involvement, 2 patients (22.2%) central nervous system involvement and 2 patients (22.2%) spleen involvement at time of diagnosis. Complex karyotype was observed in 2 patients. CHOP was given to 5 patients (55.6%), hyper-CVAD to 2 patients (22.2%), fludarabine, cyclophosphamide and mitoxantrone to 1 patient (11.1%) and cyclophosphamide, etoposide, methylprednisolone to 1 patient (11.1%) as first line chemotherapy. Four patients (44.4%) underwent allogeneic hematopoietic stem cell transplantation (AHSCT) in complete remission (CR) 1. Venetoclax was given to a transplant ineligible patient who had skin and lymph node involvement, with the off-label use. The median follow-up time was 15.9 months (3–48.6 months). Estimated median overall survival was 15.9 + 1.6 (95% CI 12.7–19.1) months.ConclusionIntensive induction therapies followed by AHSCT in CR seems to be best approaches for patients with BPDCN. Thus, more effective treatment strategies particularly targeted therapies should be warranted to improve the survival of patients with this rare disease. 相似文献
38.
Background
MUC5AC is a secreted mucin aberrantly expressed by colorectal polyps and carcinoma. It has been hypothesized that aberrant expression of MUC5AC in colorectal carcinoma tissues increased the overall survival of patients with colorectal carcinoma. The present study investigates the incidence of naturally occurring MUC5AC antibodies in the sera of normal individuals, patients with colonic polyps and patients with advanced colorectal carcinoma. A second aim was to determine the relationship of MUC5AC antibody with the prognosis of colorectal carcinoma. 相似文献39.
40.
Kiraly AP Odry BL Godoy MC Geiger B Novak CL Naidich DP 《Journal of thoracic imaging》2008,23(2):105-113
Although to date, the major impetus for the development of computer-assisted diagnosis (CAD) has been the detection of pulmonary nodules, CAD should properly be viewed as a potential tool for assisting radiologic interpretation of the entire gamut of chest diseases, including not just enhanced detection of disease but also characterization and quantification, ideally leading to improved patient management. The use of CAD to improve visualization of the airways using advanced computer techniques, including sophisticated methods for obtaining 3-dimensional segmentation of the central airways and, in particular, the development of virtual bronchoscopy has been recently studied. In this paper, the authors review the development of a specific series of CAD applications enabling automated identification and characterization of chronically inflamed airways. The advantages to the use of computer methodologies to quantify peripheral airway disease include reproducible visualization methods to display the location, severity, and extent of airway dilatation, bronchial wall thickening, and the presence of mucoid impacted airways. Currently, a number of semiquantitative global scoring systems have been proposed to assess disease extent and severity in patients with bronchiectasis. Unfortunately, with the exception of patients with cystic fibrosis, these are rarely if ever employed, largely owing to the considerable inconvenience of measuring individual airway dimensions and computing a global score. It is apparent that for this specific purpose, CAD may be ideally suited. Automated staging allows for more complete assessment of the entire bronchial tree while providing improved standardization and eliminating an otherwise tedious and time-consuming task. 相似文献