全文获取类型
收费全文 | 1646篇 |
免费 | 74篇 |
国内免费 | 8篇 |
专业分类
耳鼻咽喉 | 73篇 |
儿科学 | 102篇 |
妇产科学 | 82篇 |
基础医学 | 125篇 |
口腔科学 | 57篇 |
临床医学 | 185篇 |
内科学 | 323篇 |
皮肤病学 | 34篇 |
神经病学 | 110篇 |
特种医学 | 43篇 |
外科学 | 346篇 |
综合类 | 19篇 |
预防医学 | 47篇 |
眼科学 | 69篇 |
药学 | 58篇 |
中国医学 | 18篇 |
肿瘤学 | 37篇 |
出版年
2024年 | 4篇 |
2023年 | 11篇 |
2022年 | 21篇 |
2021年 | 55篇 |
2020年 | 40篇 |
2019年 | 42篇 |
2018年 | 44篇 |
2017年 | 31篇 |
2016年 | 55篇 |
2015年 | 59篇 |
2014年 | 63篇 |
2013年 | 86篇 |
2012年 | 91篇 |
2011年 | 102篇 |
2010年 | 58篇 |
2009年 | 61篇 |
2008年 | 114篇 |
2007年 | 128篇 |
2006年 | 126篇 |
2005年 | 133篇 |
2004年 | 110篇 |
2003年 | 64篇 |
2002年 | 72篇 |
2001年 | 37篇 |
2000年 | 30篇 |
1999年 | 35篇 |
1998年 | 7篇 |
1997年 | 6篇 |
1996年 | 7篇 |
1995年 | 1篇 |
1994年 | 3篇 |
1993年 | 3篇 |
1992年 | 4篇 |
1991年 | 3篇 |
1990年 | 3篇 |
1989年 | 2篇 |
1987年 | 2篇 |
1984年 | 1篇 |
1983年 | 2篇 |
1982年 | 2篇 |
1981年 | 1篇 |
1979年 | 1篇 |
1969年 | 1篇 |
1966年 | 1篇 |
1964年 | 1篇 |
1933年 | 1篇 |
1928年 | 1篇 |
1927年 | 2篇 |
1907年 | 1篇 |
排序方式: 共有1728条查询结果,搜索用时 12 毫秒
41.
Ethnopharmacological relevance
Salvia species and Melissa officinalis are used for their memory-enhancing effects in European folk medicine. Teucrium polium was reported to be used in Anatolia for memory-enhancement in a very old book written by an Ottoman herbalist–physician.Aim of the study
Alzheimer's disease (AD) is a progressive neurological disorder mostly affecting the elder population. Currently, there is no cure for the treatment of severe type of AD. Therefore, in this study, the hydroalcoholic extracts of three traditionally used Lamiaceae species for memory-enhancement; Salvia triloba L., Melissa officinalis L., and Teucrium polium L., were assessed for their in vivo antiamnesic activity along with in vitro anticholinesterase and antioxidant activities.Materials and methods
Scopolamine-induced antiamnesic activity was determined in mice by passive avoidance test, while anticholinesterase effect was measured by spectrophotometric Ellman method at 0.25, 0.50, 1.0, and 2.0 mg ml−1 and antioxidant activity was assessed by scavenging effect against 2,2-diphenylpicrylhydrazyl (DPPH). Total phenol contents of the extracts were determined by Folin-Ciocalteau method.Results
Salvia triloba was the most effective in antiamnesic experiment at 100, 200, and 400 mg kg−1 doses having 22.7, 57.1, and 71.4% of relative effects, respectively. Teucrium polium was also active dose-dependently, whereas Melissa officinalis was completely inactive. In the anticholinesterase assay, the extracts showed similar inhibitions against acetylcholinesterase and Teucrium polium had the highest inhibition (65.8% at 1.0 mg ml−1). Concerning the antioxidant effect, all the extracts exerted the highest activity among all having IC50 values between 0.227 and 0.428 mg/ml.Conclusion
Our data suggest that Teucrium polium among the screened plants deserves to be examined further as a herbal alternative for AD treatment. 相似文献42.
43.
44.
45.
46.
Mutlu H Berk V Karaca H Erden A Aslan T Akca Z 《Clinical and applied thrombosis/hemostasis》2012,18(5):546-548
The risk of thromboemboli is increased in patients with cancer, and this is precipitated by the chemotherapeutic agents. Bevacizumab is an anti-vascular endothelial growth factor monoclonal antibody and has an importance in the treatment of metastatic colon cancer. The association between bevacizumab, which is demonstrated to increase the risk of thromboemboli, and mean platelet volume (MPV), which is a marker of thrombocyte function, has been investigated within study. A total of 74 patients with metastatic colon cancer were included in the study and the levels of platelets (PLTs), MPV, and platecrit (PCT) values were recorded in SPSS 16.0 program both at baseline and at the >third month. There were significant decreases in 3 parameters (PLT, MPV, and PCT) during the treatment period with bevacizumab (P = .009, P = .001, and P = .000, respectively). Unlike cases with thrombosis, there is a significant decrease in MPV in combination treatments with bevacizumab. 相似文献
47.
48.
The Predictive Role of the Neutrophil/Lymphocyte Ratio in Survival with Multiple Myeloma: A Single Center Experience 下载免费PDF全文
49.
This interventional study was undertaken to assess the impact of physiotherapy education on the knowledge and attitudes of
physiotherapists (PTs) and physiotherapy students (PSs) toward euthanasia. The study, which was conducted during the period
between 2004 and 2005, included a total of 494 participants (311 PTs; 183 PSs) aged 18 to 52 y from the western and central
portions of Turkey, who responded to a self-report questionnaire (response rate, 96.4%) that was based on data from the literature.
Results indicated that PTs (48.9%) were more likely to approve of euthanasia than PSs (38.3%) (P<.05). The legalization of euthanasia was favored by 43.7% of PTs, compared with 29.5% of PSs (P<.05). On the other hand, PTs and PSs expressed similar views regarding euthanasia, including reasons for accepting or opposing
euthanasia and acceptable conditions for its use (P> .05). Overall results showed that sex and age had no effect on whether euthanasia was accepted (P> .05); religiousness was found to have the greatest effect on attitudes toward euthanasia (P<.05). The findings of the current study suggest that (1) the attitudes of PTs are different from those of PSs, and (2) the
Islamic point of view has a negative impact on the attitudes of PTs and PSs toward euthanasia. 相似文献
50.
Hakan Erenel Nevin Yilmaz Tayfur Cift Berk Bulut Isik Sozen Berna Aslan Cetin 《Hypertension in pregnancy》2017,36(4):310-314
Purpose: We aimed to compare the serum autotaxin levels in early- and late- preeclamptic and healthy pregnant patients at a university hospital.Methods: A total of 55 singleton preeclamptic women who delivered at Cerrahpasa Medical Faculty were included in the study. The patients were subdivided into two groups: early-onset preeclampsia (n = 31) and late-onset preeclampsia (n = 24). Demographic and clinical data were compared between early-onset and late-onset preeclamptic patients. The control group was composed of 32 healthy pregnant patients.Results: The mean autotaxin levels were 1.16 ± 0.97 and 0.7 ± 0.35 ng/ml in the early- and late-onset preeclampsia groups, respectively. Autotaxin levels were significantly higher in early-onset preeclampsia group compared with late-onset preeclampsia group. Autotaxin levels were found to be significantly higher in preeclamptic patients compared with control group. Serum autotaxin levels showed a significant positive correlation with maternal systolic, diastolic blood pressures and uric acid levels.Conclusion: Autotaxin might be a promising marker for detecting early-onset preeclampsia. However, further studies are necessary to confirm this hypothesis. 相似文献