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111.
112.
Bayraktar G Guvener B Bural C Uresin Y 《Journal of biomedical materials research. Part B, Applied biomaterials》2006,76(2):340-345
This study compared the influence of different polymerization methods (heat, auto-, and microwave energy), different curing processes (in the case of heat- and autopolymerized specimens), and length of storage of the polymerized specimens in distilled water at 37 degrees C on the residual methyl methacrylate (MMA) content in dental acrylic resin specimens. Residual MMA of 120 resin specimens were measured using high-performance liquid chromatography. For the heat-polymerized resins, the lowest residual MMA content was obtained when they were given a long-term terminal boil and then stored in the distilled water for at least 1 day. For the autopolymerized resins, the lowest residual MMA content was obtained when they were additionally cured in water at 60 degrees C and then stored in the distilled water at least 1 day. For the microwave-polymerized resins, the lowest residual MMA content was obtained when they were stored in the distilled water at least 1 month. The lowest overall residual MMA content was obtained from heat-polymerized specimens that were given a long-term terminal boil cure and then stored in the distilled water at least 1 day. Different polymerization methods and curing processes have different effects on residual MMA content. It is thus shown that storing a dental acrylic resin specimen in distilled water at 37 degrees C is a simple but effective method of reducing its residual MMA content. 相似文献
113.
Long-Term Effect of Interferon Therapy in Patients with HBeAg Positive Chronic Hepatitis B Infection
Hakan Senturk Birol Baysal Veysel Tahan Hasan Zerdali Resat Ozaras Fehmi Tabak Ali Mert Billur Canbakan Omur Tabak Gulsen Ozbay 《Digestive diseases and sciences》2011,56(1):208-212
Introduction
Several studies have reported that interferon therapy increases elimination rate of HBeAg and anti-HBe seroconversion in chronic hepatitis B (CHB) patients. We aimed to evaluate long-term results of interferon-α treatment in HBeAg positive CHB patients in a country with exclusively D genotype. 相似文献114.
115.
Gray R. Lyons Gulce Askin Bradley B. Pua 《Journal of vascular and interventional radiology : JVIR》2018,29(5):714-721
Purpose
To elucidate clinical variables associated with safety and efficacy in patients after cryoablation of pulmonary tumors with the use of a triple freeze protocol.Materials and Methods
Percutaneous cryoablation of pulmonary tumors was performed using Galil Medical cryoprobes (Arden Hills, Minnesota) with a triple freeze protocol: 67 nodules in 42 patients were treated at a single institution from 2012 to 2016. Average nodule diameter was 1.6 cm (range 0.4–5.9); 13 nodules (19.4%) were pathologically determined to be a primary lung malignancy, whereas 54 (80.6%) were metastatic nodules of extrapulmonary origin. Average patient age was 68.1 years (range 39.6–89.6), and the male-female ratio was 1.3:1. Ipsilateral thoracic surgery, intervention, or radiotherapy had been performed before the first cryoablation in 18 patients (42.9%). Mean imaging follow-up was 326 days (range 9–1,152).Results
Pneumothorax occurred in 19 cases (33.9%), 7 (12.5%) requiring chest tube, the likelihood of which was significantly greater in patients with 3 or more cryoprobes (P < .01). Local tumor recurrence/residual disease occurred in 6 cases (9.0%). Local tumor recurrence was not seen after ablation of nodules measuring <1.0 cm at the time of procedure, a significant difference from the recurrence ratee of 14.3% for nodules measuring ≥1.0 cm (P < .05). Likelihood of tumor recurrence/residual disease did not correlate with tumor pathology, tumor location, or procedural factors. The estimated marginal probabilities of local recurrence were 11.4%, 11.4%, and 38.1% at 1, 2, and 3 years after ablation, respectively.Conclusions
Cryoablation of pulmonary tumors with the use of a triple freeze protocol is a viable modality with low recurrence and complication rates. 相似文献116.
We have investigated the genotoxicity of lambda-cyhalothrin (LCT) (CAS registry No. 91465-08-06), a pyrethroid insecticide, in bone marrow cells and in colonic crypt epithelial cells of groups of four rats per dose treated in vivo by gavage at doses of 0.8, 3.06 and 6.12 mg/kg body weight (body wt). We measured genotoxicity using the micronucleus (MN) assay, scoring 2000 polychromatic erythrocytes (PCEs) per animal for bone marrow and 1000 colonic crypt epithelial cells per animal for the colon. We assessed cytotoxicity in bone marrow by calculating the ratio of PCEs to normochromatic erythrocytes, and in the colonic crypt epithelium by observing the frequency of binucleate cells and the mitotic index in 1000 cells. Apoptosis in colonic crypt epithelial cells was measured by observing the frequency of karyorrhexis and karyolysis in 1000 cells. We found that LCT induced a statistically significant dose-related increase in MN formation in the bone marrow and the colonic crypt. The colonic epithelium was more sensitive to the clastogenic effects of LCT than the bone marrow as judged by the significantly higher frequencies of MN in the colon than in the bone marrow at doses of 3.06 and 6.12 mg/kg body wt. 相似文献
117.
D J O'Hearn K M Leiferman F Askin S N Georas 《American journal of respiratory and critical care medicine》1999,160(4):1361-1365
Interleukin-2 (IL-2), a product of activated T-cells, is now being used in a number of protocols for cancer immunotherapy. In one stem cell transplantation protocol for breast cancer, IL-2 is used together with interferon-gamma (IFN-gamma) and cyclosporine to stimulate a graft-versus-tumor response and improve the likelihood of a prolonged remission. We present the case of a patient who developed peripheral eosinophilia, perihilar infiltrates, and hypoxemia after autologous stem cell transplantation and the use of recombinant IL-2 and IFN-gamma. Histologic analysis of transbronchial lung biopsies demonstrated a few eosinophils within the bronchial submucosa. Immunostaining using antibodies directed against eosinophil major basic protein (MBP), however, revealed massive extracellular deposition of this toxic granule protein throughout the lung parenchyma. IL-2 therapy is well known to induce a peripheral eosinophilia and to be associated with the capillary leak syndrome characterized by weight gain, edema, and oliguria. The findings noted in this case report suggest that the eosinophil activation that accompanies immunologic therapy with IL-2 can result in direct toxicity to the lung and a localized vascular leak syndrome. This syndrome should be considered in the differential diagnosis of pulmonary infiltrates that occur acutely after bone marrow transplantation with cytokine augmentation. 相似文献
118.
Glomerulocystic kidney. 总被引:1,自引:0,他引:1
W H McAlister M J Siegel G Shackelford F Askin J M Kissane 《AJR. American journal of roentgenology》1979,133(3):536-538
119.
120.