Health related quality of life in elderly people living in Bandar Abbas, Iran: a population-based study

Measuring health related quality of life of old people has become an important public health issue with the aging of population in developing countries. The aim of this study was to examine the health related quality of life of old people living in Bandar Abbas, Iran. This was a population-based study in which a random sample of 1000 individuals of the community aged over 60 years were interviewed using SF-36 questionnaire. Overall health related quality of life and relative differences between men and women and also between different age groups (60-75 years vs. >75 years) was assessed in this study. A total of 1000 elderly individuals completed the SF-36 questionnaire. Of all participants 499 (49.9%) were men, 501 (50.01%) women, 789 (78.9%) aged 60-75 years, and 211 (21.1) aged over 75 years. The logistic regression analysis showed the age over 75 years could increase the risk of lower score of physical [OR: 2.69, CI; (1.96-3.73] and mental [OR: 1.58, CI (1.16-2.15)] component summaries of SF-36 regardless other factors. Additionally, suffering from chronic diseases could decrease physical and mental scores of health related quality of life separately [OR: 8.6, CI; (4.37-16.94) and OR: 1.8, CI (1.1-2.99) respectively]. Women compared to men and illiterate old people compared to literate ones are more likely to perceive worse health related quality of life especially in physical component [OR: 1.35, CI; (1.01-1.81) and OR: 1.59, CI (1.12-2.24) respectively]. The findings of this study suggest that health related quality of life in old people is not only decreased by aging, but each of other factors such as female gender, illiteracy, and chronic diseases could decrease health related quality of life of old people.     

Final oocyte maturation with a dual trigger compared to human chorionic gonadotropin trigger in antagonist co-treated cycles: A randomized clinical trial

Objective

This clinical trial compared the effect of a dual trigger treatment (combination of gonadotropin-releasing hormone (GnRH) agonist and human chorionic gonadotropin (hCG) and hCG alone on oocyte quality and metaphase II oocytes’ number.

Effect of ethanolic extract of Juglans regia L. on blood sugar in diabetes-induced rats

Walnut is one of the medicinal plants used in traditional Iranian medicine as a treatment for diabetes, but little scientific documentation supports its antidiabetic action. This study is designed to evaluate the antidiabetic effect of ethanolic walnut leaf extract. Twenty-four male Wistar rats were divided into four groups: nondiabetic rats, alloxan-induced diabetic rats with no treatment, alloxan-induced diabetic rats treated with ethanolic extracts of Juglans regia (200 mg/kg), and alloxan-induced diabetic rats treated with glibenclamide (0.6 mg/kg). Fasting blood sugar decreased meaningfully in diabetic rats treated with J. regia and diabetic rats treated with glibenclamide. Insulin level increased and glycosylated hemoglobin decreased significantly in diabetic groups receiving either glibenclamide or J. regia compared with the diabetic group with no treatment. The histological study revealed that the size of islets of Langerhans enlarged consequentially as compared with diabetic rats with no treatment. Effects of administering glibenclamide or extract of J. regia on all parameters discussed above showed no difference, and both tended to bring the values to near normal. Our data show the ethanolic extract from leaves of J. regia has a dramatic antidiabetic effect on diabetes-induced rats.     

Investigation of the Lipid-Modifying and Antiinflammatory Effects of Cornus mas L. Supplementation on Dyslipidemic Children and Adolescents

Cornus mas L. (CM) fruits are rich in anthocyanins and possess both antiinflammatory and antioxidant activities. The current study was conducted to investigate whether supplementation with CM could ameliorate lipid profile and vascular inflammation in dyslipidemic children and adolescents. In this randomized clinical trial, 40 dyslipidemic children and adolescents ages 9 to 16 years were assigned to receive 50 g of CM twice a day after lunch and dinner (n = 20, case group) or to continue their normal diet (n = 20, control group). The serum levels of total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), triglycerides (TG), apo A-I, apo B, intracellular adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule-1 (VCAM-1), C-reactive protein (CRP), and anthropometric indices were determined at baseline and then after weeks 3 and 6 of the trial. After week 6 of the trial, the TC, TG, LDL-C, apo B, ICAM-1, and VCAM-1 levels in the CM group were significantly lower and the HDL-C and apo A-I levels higher than at baseline. After week 6 of the trial, none of these parameters in the control group, except for ICAM-1, was significantly altered from baseline. However, between-group comparison showed a significant difference only for apo A-I (p = 0.016) and a borderline significant difference for ICAM-1 (p = 0.076). No significant difference in body mass index, waist-to-hip ratio, or C-reactive protein was observed between the studied groups. The present findings revealed a trend toward amelioration of lipid profile and vascular inflammation following addition of CM to the daily diet of dyslipidemic children and adolescents but this needs to be verified by larger scale trials.     

A comparison of the effect of short-term aromatase inhibitor (letrozole) and GnRH agonist (triptorelin) versus case control on pregnancy rate and symptom and sign recurrence after laparoscopic treatment of endometriosis

Purpose  

To compare the role of an aromatase inhibitor (letrozole) with a GnRH agonist (triptorelin) versus case control on the pregnancy rate and recurrence of symptoms and signs in patients with endometriosis.     

Identification of perceived barriers of pain management in Iranian children: a qualitative study

Hospitalized children are often inadequately treated for their pain. Paediatric nurses experience these inadequacies more than other health-care team members. This research was an attempt in the form of a phenomenological study to reveal some major barriers in children pain management as the nurses had perceived. Sixteen nurses were interviewed in the medical, surgical and infectious paediatric wards of a hospital in Iran. Data analysis were based on Colaizzi method that surfaced three main themes in different areas namely: organizational barriers, limitations relating to child's characteristics and barriers relating to the nature of disease and its treatments. The study results have shown organizational limitations added to the lack of authority for administering some medical intervention, inadequate equipment and utilities and unavailability of opioids as the main pain controlling and restricting factors. Additional factors that relate to the child specifications like age, temperament, behaviour, expression and gender affect the assessment and treatment of pain. The results revealed identified barriers in real context. It seems that some guidelines are needed to achieve optimal pain management.     

Prevalence and trends of human immunodeficiency virus, hepatitis B virus, and hepatitis C virus among blood donors in Iran, 2004 through 2007

BACKGROUND: Evaluation and monitoring the prevalence of transfusion-transmissible viral infections in blood donors is a valuable index of donor selection and blood safety. This study analyzed the trends of blood-borne infections among Iranian blood donations during 4 years.
STUDY DESIGN AND METHODS: Viral screening results of 6,499,851 allogeneic donations from 2004 through 2007 were analyzed. All donations were screened for hepatitis B virus (HBV), hepatitis C virus (HCV), human immunodeficiency virus (HIV), and syphilis. The prevalence of HBV, HCV, and HIV infections per 100,000 donations and 95% confidence interval was calculated. The p value was estimated by chi-square test.
RESULTS: The prevalences of HBV, HCV, and HIV decreased during the 4-year study from 2004 through 2007. The overall prevalence was 0.56% for HBV, 0.004% for HIV, and 0.13% for HCV. There was a significant and impressive decrease in hepatitis B surface antigen prevalence from 0.73% in 2004 to 0.41% in 2007. The prevalence of HIV appeared to have decreased from 0.005% in 2004 to 0.004% in 2007 although the decrease was not significant. HCV prevalence showed a slight decline in blood donations from 0.14% in 2005 to 0.12% in 2007.
CONCLUSION: The trends of transfusion-transmitted infection prevalence in Iranian blood donations suggest that most of the safety measures employed in recent years in Iran have been effective.     

MULTIPLE SMOOTH MUSCLE HAMARTOMA: CASE REPORT AND REVIEW OF THE LITERATURE

Smooth muscle hamartoma (SMH) is a proliferative disorder of cells originating from muscle cells. It is a benign tumoral mass that usually presents as a single congenital skin-colored and hypertrichotic plaque involving the trunk and extremities. Multiple SMHs have rarely been reported in the literature. We describe the case of a seven-month-old girl with multiple SMHs located over the back and arm areas. The diagnosis was confirmed by biopsy and immunohistochemical (IHC) staining. She had no cerebral or skeletal abnormalities and her growth and development were normal.