On the instantaneous measurement of bloodflow by ultrasonic means

Part of the problem of determining the flow through a blood vessel is the measurement of the instantaneous average blood velocity over a cross-section of the vessel. In this paper a new method is described to estimate that velocity from the received signal of a Doppler flowmeter using continuous ultrasound. The method is based on the determination of the frequency shift averaged over the power density spectrum of the received signal. Due to a new type of instrumentation this can be done without carrying through a complete frequency analysis of that signal. This provides a rather accurate determination of the instantaneous value of the blood velocity.     

Long-term effect of glucocorticosteroids on neuromuscular blocking in mice.

The effect of dexamethasone, given thrice weekly, on neuromuscular blocking by D-tubocurarine was studied in mice. Dexamethasone antagonised the effect of D-tubocurarine. This antagonism developed gradually during the first two weeks of treatment. The possible relationship between this finding and the beneficial effect of glucocorticosteroids in patients with myasthenia gravis is discussed.