全文获取类型
收费全文 | 76874篇 |
免费 | 4853篇 |
国内免费 | 314篇 |
专业分类
耳鼻咽喉 | 801篇 |
儿科学 | 2202篇 |
妇产科学 | 1777篇 |
基础医学 | 11289篇 |
口腔科学 | 5004篇 |
临床医学 | 6621篇 |
内科学 | 16191篇 |
皮肤病学 | 1951篇 |
神经病学 | 6497篇 |
特种医学 | 1627篇 |
外国民族医学 | 2篇 |
外科学 | 7555篇 |
综合类 | 652篇 |
一般理论 | 37篇 |
预防医学 | 8483篇 |
眼科学 | 1163篇 |
药学 | 5637篇 |
中国医学 | 545篇 |
肿瘤学 | 4007篇 |
出版年
2023年 | 699篇 |
2022年 | 1344篇 |
2021年 | 2980篇 |
2020年 | 1853篇 |
2019年 | 2515篇 |
2018年 | 2993篇 |
2017年 | 2119篇 |
2016年 | 2146篇 |
2015年 | 2621篇 |
2014年 | 3420篇 |
2013年 | 4270篇 |
2012年 | 6426篇 |
2011年 | 6847篇 |
2010年 | 3508篇 |
2009年 | 2865篇 |
2008年 | 4776篇 |
2007年 | 4787篇 |
2006年 | 4191篇 |
2005年 | 3741篇 |
2004年 | 3269篇 |
2003年 | 2983篇 |
2002年 | 2634篇 |
2001年 | 937篇 |
2000年 | 934篇 |
1999年 | 838篇 |
1998年 | 493篇 |
1997年 | 385篇 |
1996年 | 299篇 |
1995年 | 272篇 |
1994年 | 244篇 |
1993年 | 193篇 |
1992年 | 383篇 |
1991年 | 327篇 |
1990年 | 315篇 |
1989年 | 303篇 |
1988年 | 274篇 |
1987年 | 212篇 |
1986年 | 222篇 |
1985年 | 202篇 |
1984年 | 169篇 |
1983年 | 154篇 |
1982年 | 114篇 |
1981年 | 109篇 |
1979年 | 144篇 |
1978年 | 132篇 |
1975年 | 96篇 |
1974年 | 105篇 |
1973年 | 105篇 |
1970年 | 102篇 |
1969年 | 100篇 |
排序方式: 共有10000条查询结果,搜索用时 125 毫秒
991.
Rita G. Hamilton DO Steven W. Brown MD Michael Miner MD PhD 《The journal of spinal cord medicine》2013,36(1):95-98
Background/Objective: Pseudomeningocele is most commonly the result of a rent in the meninges during spine surgery. Noniatrogenic causes exist but are rare. Pseudomeningoceles may heal spontaneously, but they may also slowly enlarge. They rarely present as a mass within the abdomen. The objective of this study was to present the first case report of hydronephrosis secondary to lumbar pseudomeningocele.Design: Single case report and literature review.Methods: Single case report.Results: This man had undergone extensive lumbar spine surgery for pain and spondylolisthesis. He subsequently developed a pseudomeningocele that caused hydronephrosis of the left kidney. He was treated with surgical intervention and had resolution of his hydronephrosis and his flank and groin pain. He also had improvement of his back pain.Conclusions: This report shows an unusual cause of hydronephrosis—a pseudomeningocele presenting as an abdominal mass that compressed the ureter. 相似文献
992.
Rafael Valencia-Quintana Sandra Gómez-Arroyo Stefan Marian Waliszewski Juana Sánchez-Alarcón José Luis Gómez-Olivares Ana Rosa Flores-Márquez Josefina Cortés-Eslava Rafael Villalobos-Pietrini 《Toxicology and Environmental Health Sciences》2012,4(3):154-160
Dimethyl sulfoxide (DMSO) is an organic solvent with several biological applications. It is extensively used to dissolve compounds that hardly dissolve in water to detect their genotoxic activity in vitro. In this study DMSO will be tested to determine its genotoxic potential. The effect of DMSO on the frequency of chromosomal aberrations in anaphase as well as DNA fragmentation through the comet assay has been evaluated in the meristematic cells of the root tips of Vicia faba. It has been observed that the frequency of chromosomal aberrations increases when the concentration of DMSO increases, reaching its maximum value with 20% of DMSO and decreasing at 30 and 40% of DMSO, in comparison to this maximum value, but significantly higher than the values observed in the control. Similarly, the percentage of fragmentation and damage index evaluated through the comet assay showed the same behavior; some of the possible mechanisms of action are discussed. 相似文献
993.
994.
Eduardo Alexandre Loth Samia Khalil Biazim José Henrique Fermino Ferreira dos Santos Rosana Puccia Rosimeire Costa Brancalh?o Lucinéia de Fátima Chasco Rinaldo Ferreira Gandra Rita de Cássia Garcia Sim?o Marcello Fabiano de Franco 《Revista do Instituto de Medicina Tropical de S?o Paulo》2014,56(3):259-264
Paracoccidioidomycosis (PCM) is caused by the dimorphic fungus
Paracoccidioides brasiliensis (Pb) and corresponds to prevalent
systemic mycosis in Latin America. The aim of the present work was to evaluate the
dose response effect of the fungal yeast phase for the standardization of an
experimental model of septic arthritis. The experiments were performed with groups of
14 rats that received doses of 103, 104 or 105
P. brasiliensis (Pb18) cells. The fungi were injected in 50 µL of
phosphate-buffered saline (PBS) directly into the knee joints of the animals. The
following parameters were analyzed in this work: the formation of swelling in knees
infused with yeast cells and the radiological and anatomopathological alterations,
besides antibody titer by ELISA. After 15 days of infection, signs of inflammation
were evident. At 45 days, some features of damage and necrosis were observed in the
articular cartilage. The systemic dissemination of the fungus was observed in 11% of
the inoculated animals, and it was concluded that the experimental model is able to
mimic articular PCM in humans and that the dose of 105 yeast cells can be
used as standard in this model. 相似文献
995.
996.
997.
Ana Dorcas de Melo Inagaki Cristina Gardonyi Carvalheiro Rosana Cipolotti Ricardo Queiroz Gurgel Dayse Alves Rocha Kariny Souza Pinheiro Raquel Melo Araújo Dorothy Ribeiro Resende Lima Jacques Leon Winandy Marisa Márcia Mussi‐Pinhata 《Tropical medicine & international health : TM & IH》2012,17(11):1349-1355
Objectives To estimate, by neonatal screening, the birth prevalence of congenital toxoplasmosis among live‐born infants in Sergipe state, Brazil, and to investigate the clinical features of affected infants. Methods Dried blood spot specimens obtained from 15 204 neonates were assayed for the presence of anti‐T. gondii IgM antibodies. Duplicate retesting was done in infants with positive and borderline results. Confirmatory testing in peripheral blood samples consisted of testing for anti‐T. gondii IgG and IgM in infants and mothers. Those with possible congenital toxoplasmosis were evaluated and followed up to a median age of 20 months. Congenital infection was confirmed in the presence of persisting anti‐T. gondii IgG antibodies beyond 12 months of age. All infants with confirmed infection were treated with pyrimethamine, sulfadiazine and folinic acid for 1 year. Results Fifty‐three infants had detectable IgM in dried blood spot specimens. Confirmatory testing was reactive in 39/50, of which, 38 completed follow‐up. Six of 15 204 newborns were diagnosed with congenital toxoplasmosis, resulting in an estimated birth prevalence of four per 10 000 [CI 95% 1.4–8.0]. Four infants (67%) showed signs of congenital toxoplasmosis in their first year of life; three (75%) had retinochoroidal scars, and one had cerebral calcifications. Two infants remained asymptomatic until 20 months of age. Conclusions The birth prevalence of congenital toxoplasmosis is high in the Brazilian state of Sergipe, with most of the infants showing ocular lesions. Preventive measures are strongly warranted. 相似文献
998.
999.
Reliability of a two‐colour chewing gum test to assess masticatory performance in complete denture wearers
下载免费PDF全文
![点击此处可从《Journal of oral rehabilitation》网站下载免费的PDF全文](/ch/ext_images/free.gif)
L. C. Silva T. E. Nogueira L. F. Rios M. Schimmel C. R. Leles 《Journal of oral rehabilitation》2018,45(4):301-307
The aim of this study was to test the reliability of a method to measure the masticatory performance of complete denture wearers employing a colour‐mixing ability test and assessment by visual and electronic colourimetric analysis. A sample of 75 subjects was selected from patients who received new conventional complete dentures. Masticatory tests were performed using a two‐colour chewing gum that was masticated for 5, 10, 20, 30 and 50 chewing cycles, performed in a random order. The mixing level of the two colours of the chewed gum was assessed visually by two independent raters based on a 5‐point ordinal scale. The specimens were flattened into a 1‐mm‐width wafer, scanned and saved as a two‐sided digital image. Each pair of images was submitted to an electronic colourimetric analysis to assess the level of colour mixture, measured by the circular variance of hue (VOH ). Overall inter‐ and intra‐rater agreements in visual analysis were 64% and 68%, respectively (almost 99% of scores ranged within ±1 point), whilst overall weighted kappa was >0.80. A proportional increase in the level of mixture occurred with increased number of chewing cycles (P < .001). Similarly, VOH and the visual analysis were highly correlated (r = ?.89; P < .001). Bland‐Altman plots revealed excellent agreement and extremely low systematic error between duplicated VOH measures. It was concluded that the two‐colour chewing gum test is a reliable method to assess the masticatory performance in complete denture wearers using both visual and electronic colourimetric analyses. 相似文献