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排序方式: 共有1247条查询结果,搜索用时 15 毫秒
21.
Ter Schiphorst Adrien Gaillard Nicolas Dargazanli Cyril Mourand Isabelle Corti Lucas Charif Mahmoud Ayrignac Xavier Lippi Anaïs Bouly Stéphane Thibault Lalu Sablot Denis Blanchet-Fourcade Genevieve Landragin Nicolas Costalat Vincent Duflos Claire Arquizan Caroline 《Journal of neurology》2021,268(1):346-355
Journal of Neurology - Symptomatic isolated carotid artery occlusions (ICAO) can lead to disability, recurrent stroke, and mortality, but natural history and best therapeutic management remain... 相似文献
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Manuel Zorzi Nicola Gennaro Giulia Capodaglio Emanuele Damiano Luca Urso Salvatore Pucciarelli Laura Memo Eva Carpin Mariachiara Corti Massimo Rugge Ugo Fedeli 《Digestive and liver disease》2019,51(2):304-309
Background
Growing evidence suggests that colorectal cancer (CRC) screening based on the fecal immunochemical test (FIT) reduces CRC incidence and surgical resection rates.Aims
To compare trends in surgery for proximal and distal CRC among Italian regions at different stages of screening implementation.Methods
From the National Hospital Discharge Database we selected hospitalizations with CRC resection of residents aged 50–74 years during 2002–2014, and computed surgery rates for the 8 most populous Italian regions with/without a screening program.Results
In regions with screening, implemented around 2006–2007, the annual percent change (APC) of distal CRC resection was +1.7 (95% confidence interval ?1.0, 4.4) during 2002–2007 and ?9.1 (?10.6, ?7.7) during 2007–2014. No significant change was observed in regions without screening. The APC for proximal colon resection in regions with screening was +5.8 (2.5, 9.0) during 2002–2007 and ?4.1 (?5.8, ?2.4) during 2007–2014, while in regions without screening surgical rates increased through the whole study period. Compared to 2002, in 2014 distal CRC resection rates were greatly reduced in regions with screening, reaching values similar to proximal CRC resection.Conclusion
Following the implementation of screening programs surgery rates steeply decreased, confirming the deep impact of FIT-based screening on the burden of CRC. 相似文献24.
Raffaella Nenna MD Paola Papoff MD Corrado Moretti MD Daniela De Angelis MD Massimo Battaglia MD Stefano Papasso MD Mariangela Bernabucci MD Giulia Cangiano MD Laura Petrarca MD Serena Salvadei MD Ambra Nicolai MD Marianna Ferrara MD Enea Bonci MD Fabio Midulla MD 《Pediatric pulmonology》2014,49(9):919-925
25.
Vera Lúcia Corti?o Corrêa Rodrigues Clovis Pauliquevis Junior Rubens Antonio da Silva Dalva Marli Valério Wanderley Marluci Monteiro Guirardo Lilian Aparecida Colebrusco Rodas Claudio Casanova Marcio L. Pachioni Wilson A. Souza Abílio Jose Batista Costa Delvo Baitelo Vera Lúcia Braga Tonietti 《Revista do Instituto de Medicina Tropical de S?o Paulo》2014,56(3):213-218
The objective of this study is to report on the colonization of palm trees
by Rhodnius neglectus, its invasion in an urban area, in Araçatuba -
São Paulo, and the control and surveillance measures that have been put in place.
Domiciliary triatomine searches occurred in apartments upon the inhabitants''
notification. The collected insects were identified and examined for natural
infection and food sources with a precipitin test. To search the palm trees, tarps
were used to cover the floor, and a “Munck” truck equipped with a tree-pruning device
was utilized. Chemical control was performed with the utilization of a manual
compression. In 2009, 81 specimens of Rhodnius neglectus were
collected from the domiciles by the population. The precipitin test revealed a
presence of human blood in 2.7% of the samples. Entomological studies were carried
out in these domiciles and in those located within a radius of 200 meters. The search
performed in the palm trees resulted in the capture of 882 specimens of triatomines,
negative for tripanosomatids. Mechanical and chemical controls were carried out. New
searches conducted in the palm trees in the same year resulted in the capture of six
specimens. The mechanical and chemical controls of the palm trees, together with the
population''s work, proved to be effective, therefore preventing these insects''
colonization of the city''s domiciles. 相似文献
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Francesca Novara Ambra Rizzo Gloria Bedini Vita Girgenti Silvia Esposito Chiara Pantaleoni Roberto Ciccone Francesca L. Sciacca Valentina Achille Erika Della Mina Simone Gana Orsetta Zuffardi Margherita Estienne 《European journal of medical genetics》2013,56(5):260-265
5q14.3 deletions including the MEF2C gene have been identified to date using genomic arrays in patients with severe developmental delay or intellectual disability, stereotypic behavior, epilepsy, cerebral malformations and a facial gestalt not really distinctive though characterized by broad and/or high, bulging forehead, upslanting palpebral fissures, flat nasal root and bridge, small, upturned nose, hypotonic small mouth resulting in cupid bow/tented upper lip. MEF2C mutations have been also identified in patients with overlapping phenotype so that it is considered the gene responsible for the 5q14.3 deletion syndrome. To date, one single duplication including MEF2C has been reported in a patient with intellectual disability but its clinical significance remains uncertain also because of the large size of the imbalance. Here we present two further patients with 5q14.3 duplications including MEF2C. Their phenotype indeed suggest the pathogenic effect of the MEF2C duplication although other duplicated genes also brain expressed might contribute to the clinical features. In none of them a clear-cut syndrome can be identified. A comparison between MEF2C deleted/mutated and duplicated patients is also presented. 相似文献
28.
Gruner C Akkaya E Kretschmar O Roffi M Corti R Jenni R Eberli FR 《Journal of interventional cardiology》2012,25(5):505-512
Objectives: The aim of this study was to assess whether transient atrial septal defect (ASD) occlusion and, if required, vasodilator therapy would improve the safety of percutaneous ASD closure in high-risk subsets. Background: While percutaneous ASD closure is generally considered a low risk intervention, hypertensive and elderly patients may develop pulmonary edema following the procedure because of underlying left ventricular (LV) diastolic dysfunction. Methods: Fifty-two consecutive patients who underwent successful percutaneous ASD closures were enrolled into a single-center prospective registry. Patients with arterial hypertension and/or >60 years of age (n = 15) were considered at risk for periprocedural pulmonary edema. Those patients were tested for an increase of LV filling pressures during transient ASD occlusion and, if this was the case, treated according to a prespecified algorithm. Clinical and echocardiography data were collected in-hospital and at 6 months follow-up. Results: Shunt size was comparable in high and standard-risk patients (Qp:Qs 2.1 ± 0.8 vs. 2.1 ± 0.7, P = 0.82). High-risk patients had more often pulmonary hypertension (58% vs. 14%, P < 0.05) and were more frequently symptomatic. Among them, 4/15 (27%) demonstrated a significant rise of left-sided filling pressures during transient ASD balloon occlusion and underwent pharmacologic preconditioning prior to ASD closure. None of them developed periprocedural pulmonary edema. At follow-up, patients were less symptomatic (Pre: NYHA II n = 15, NYHA III n = 9; Post: NYHA II n = 15, NYHA III n = 0; P = 0.02) and right ventricular size decreased from 23 ± 5 cm(2) to 17 ± 5 cm(2) , P < 0.05. Conclusion: Transient ASD occlusion and, if required, pharmacologic preconditioning prior to percutaneous closure may prevent periprocedural pulmonary edema in high-risk patients. (J Interven Cardiol 2012;25:505-512). 相似文献
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30.
Background: The systemic use of combined amoxicillin and metronidazole (AMX/MET) as an adjunctive treatment to full‐mouth scaling and root planing (FMSRP) has been proposed for the treatment of generalized aggressive periodontitis; however, its effectiveness and clinical safety remain to be defined. The purpose of the present meta‐analysis is to assess the effectiveness of FMSRP + AMX/MET compared to FMSRP alone. Methods: An electronic search of eight databases and a hand‐search of 10 international dental journals were conducted through September 11, 2011. Gain in clinical attachment level (CAL), reduction in probing depth (PD), secondary outcomes, and adverse events were analyzed. A random‐effect model was used to pool the extracted data. The weighted mean difference (MD) with 95% confidence interval (CI) was calculated for continuous outcomes, whereas risk difference (RD) with 95% CI was used for dichotomous data; heterogeneity was assessed with the χ2‐based Cochran Q test and I2 statistic. The level of significance was set at P <0.05. Results: After the selection process, six randomized clinical trials were included. Results of the meta‐analysis showed significant CAL gain (MD, 0.42; 95% CI, 0.23 to 0.61; P <0.05) and PD reduction (MD, 0.58; 95% CI, 0.39 to 0.77; P <0.05) in favor of FMSRP + AMX/MET; moreover, no significant RD was found in the occurrence of adverse events (RD, 0.01; 95% CI, ?0.02 to 0.04; P >0.05). Conclusion: The findings of the meta‐analysis seem to support the effectiveness and the clinical safety of FMSRP + AMX/MET; however, future studies are needed to confirm these results. 相似文献