Modeling oxygen transport in surgical tissue transfer

Reconstructive microsurgery is a clinical technique used to transfer large amounts of a patient''s tissue from one location used to another in order to restore physical deformities caused by trauma, tumors, or congenital abnormalities. The trend in this field is to transfer tissue using increasingly smaller blood vessels, which decreases problems associated with tissue harvest but increases the possibility that blood supply to the transferred tissue may not be adequate for healing. It would thus be helpful to surgeons to understand the relationship between the tissue volume and blood vessel diameter to ensure success in these operations. As a first step towards addressing this question, we present a simple mathematical model that might be used to predict successful tissue transfer based on blood vessel diameter, tissue volume, and oxygen delivery.     

Disseminated porokeratosis of Mibelli: A case report

Porokeratosis is a disorder of clonal hyperproliferation of keratinocytes with several different clinical manifestations. Cutaneous lesions vary in their appearance and distribution. All variants share the distinguishing cornoid lamella on histopathological examination. We present an unusual case of disseminated porokeratosis of Mibelli in an immunocompetent patient.     

Desmoplastic fibroma of the frontal bone

Desmoplastic fibroma is a benign but locally aggressive tumor arising usually from the mandible, pelvis and long bones with a potential for recurrence. We report a case of desmoplastic fibroma of the frontal bone in a young male.     

Effect of Pneumoperitoneum and Patient Positioning on Intracranial Pressures during Laparoscopy: A Prospective Comparative Study

Study Objective

To evaluate the effect of pneumoperitoneum and head position during laparoscopic surgery on intracranial pressures (ICPs) using sonographic measurements of optic nerve sheath diameter (ONSD).

Tear inflammatory mediators and protein in eyes of post allogenic hematopoeitic stem cell transplant patients

Aim

To analyze tear cytokines levels and their correlation to ocular surface parameters in allogenic hematopoietic stem cell transplants (allo-HSCT) patients.

Head tremor at disease onset: an ataxic phenotype of cervical dystonia

Journal of Neurology - Cervical dystonia (CD) can present with head tremor. It is unclear whether ataxic features are differentially associated with this phenotype at onset of CD. We sought to...     

Rhamnolipids from the rhizosphere bacterium Pseudomonas sp. GRP(3) that reduces damping-off disease in Chilli and tomato nurseries

A detailed screening of bacterial isolates from the Central Himalayan region for plant growth promotion and antimycelial activity against Pythium and Phytophthora strains afforded seven isolates, of which three were particularly effective against the incidence of damping-off in field trials on chilli and tomato. In this investigation an initial spectroscopic survey of the methanolic extracts of the seven bacterial isolates showed complex mixtures except for Pseudomonas sp. GRP3, one of the most promising isolates on the basis of field studies. Strain GRP3 was selected for structural characterization of its secondary metabolites, particularly glycolipids. The extracellular secondary metabolites were enriched by Amberlite XAD-16 adsorber resin followed by separation and structural analysis using TLC, LC-MS, MS-MS, and NMR spectroscopy. Acquired data show the presence of a number of mono- and dirhamnolipids and include rhamnose (Rha)-C8-C10, Rha-C10-C8, Rha-C10-C10, Rha-C10-C12:1, Rha-C10-C12, Rha-Rha-C8-C10, Rha-Rha-C10-C10, Rha-Rha-C10-C10:1, Rha-Rha-C10-C12, Rha-Rha-C10-C12:1, Rha-Rha-C12-C12:1, and Rha-Rha-C12-C12 in strain GRP3. Since rhamnolipids are involved in the lysis of the plasma membrane of zoospores of fungi, application of such rhamnolipid-producing rhizobacteria could facilitate control of damping-off plant pathogens.