全文获取类型
收费全文 | 55081篇 |
免费 | 2905篇 |
国内免费 | 192篇 |
专业分类
耳鼻咽喉 | 1213篇 |
儿科学 | 2584篇 |
妇产科学 | 1551篇 |
基础医学 | 5805篇 |
口腔科学 | 3606篇 |
临床医学 | 3741篇 |
内科学 | 11885篇 |
皮肤病学 | 1538篇 |
神经病学 | 4558篇 |
特种医学 | 1684篇 |
外国民族医学 | 1篇 |
外科学 | 8653篇 |
综合类 | 557篇 |
一般理论 | 14篇 |
预防医学 | 3660篇 |
眼科学 | 1498篇 |
药学 | 3577篇 |
中国医学 | 349篇 |
肿瘤学 | 1704篇 |
出版年
2024年 | 56篇 |
2023年 | 579篇 |
2022年 | 963篇 |
2021年 | 1838篇 |
2020年 | 1120篇 |
2019年 | 1537篇 |
2018年 | 2138篇 |
2017年 | 1514篇 |
2016年 | 1722篇 |
2015年 | 1726篇 |
2014年 | 2454篇 |
2013年 | 3098篇 |
2012年 | 3998篇 |
2011年 | 4184篇 |
2010年 | 2405篇 |
2009年 | 1835篇 |
2008年 | 3037篇 |
2007年 | 3027篇 |
2006年 | 2911篇 |
2005年 | 2727篇 |
2004年 | 2668篇 |
2003年 | 2303篇 |
2002年 | 2191篇 |
2001年 | 1453篇 |
2000年 | 1349篇 |
1999年 | 1105篇 |
1998年 | 381篇 |
1997年 | 265篇 |
1996年 | 252篇 |
1995年 | 164篇 |
1994年 | 157篇 |
1993年 | 108篇 |
1992年 | 326篇 |
1991年 | 311篇 |
1990年 | 269篇 |
1989年 | 226篇 |
1988年 | 202篇 |
1987年 | 179篇 |
1986年 | 150篇 |
1985年 | 137篇 |
1984年 | 118篇 |
1983年 | 99篇 |
1981年 | 46篇 |
1979年 | 81篇 |
1978年 | 62篇 |
1973年 | 45篇 |
1972年 | 49篇 |
1971年 | 56篇 |
1967年 | 66篇 |
1966年 | 45篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
101.
102.
M Abbes C Boursault D Conso E Roméo 《Annales de chirurgie plastique et esthétique》1992,37(4):394-401
Based on a series of 220 cases of reconstruction (63 cases) or correction (67 cases) of the nipple-areolar complex and various extramammary procedures (tattoo scar revision, lips, eyebrows, eyelashes) (90 cases), the authors present their 2-year experience of medical dermography in a cancer centre. Dermography allows breast reconstruction to be completed in a large number of patients who had initially refused to complete their reconstruction. This minimally aggressive outpatient technique which reconstitutes the areolo-nipple complex with sufficient quality, is now part of reconstruction protocols and is gradually replacing surgical techniques. 相似文献
103.
F Ledesma Casta?o S Echevarria Vierna J L Lozano Polo R Oloriz Rivas C Alvarez Moreno F Pons Romero 《European journal of clinical nutrition》1992,46(7):527-533
Interleukin-1 (IL-1) is a cytokine produced by the macrophage-monocyte system that has important effects on immunological responses and inflammatory reactions. Several clinical studies have shown that severe protein energy malnutrition adversely effects cell-mediated immune responses and the functional state of macrophages. The objective of this study was to analyse IL-1 production by adherent cells stimulated in vitro with lipopolysaccharide B (LPS) from patients with alcoholic cirrhosis of the liver and its possible relationship with nutritional states. Forty-five patients with alcoholic cirrhosis and 28 healthy donors were investigated. A combined index of nine anthropometric and biochemical parameters was used to evaluate nutritional status of cirrhotic patients, allowing a distinction to be made between those patients with acceptable nutrition (group I: 40%), those with slight malnutrition (group II: 37.7%), and those with severe malnutrition (group III: 22.3%). IL-1 activity was significantly lower in the cirrhosis patients than in the controls (P less than 0.001). This activity also was significantly lower in samples obtained from cirrhotics with severe malnutrition than in those with acceptable nutrition (P less than 0.05); the combined index and the sole anthropometric index gave the same results, suggesting that malnutrition may play a role in the immunoregulatory disturbances in the pathogenesis of alcoholic liver disease. 相似文献
104.
R. Yavuzer Ö. Tascilar E. Tekin O. Latifoğlu G. Akyol A. Dursun F. Taneri 《European journal of plastic surgery》1997,20(6):306-309
Diethyl maleate (DEM) which binds and thus depletes tissue glutathione levels was used to aggravate the injury and to determine its effect on incisional healing. A 5 cm dorsal midline skin incision was performed on 40 albino Wistar rats in two groups and then closed by interrupted sutures. Groups received 0.9% NaCl and DEM at a dosage of 1 mg/kg/day intraperitoneally for seven days, respectively. On postoperative days 7 and 14, histopathological assessment and tensile strengths were measured. The DEM treated group had a marked inflammation with poorly defined collagen formation and the tensile strength measurements revealed a significant decrease (p <0.001) on the 7t day. On the other hand, the first group showed better collagenization and a lesser degree of inflammation. However, on the 14th day, there was no noticeable histopathological difference between the two groups; but, tensile strength values of the second group were still lower (p <0.05). In this animal model, DEM postponed the healing process and reduced the tensile strength. 相似文献
105.
106.
Egidio L. Romano res Soyano Ramón F. Montaño Murray Ratcliffe Marilyn Olson Guillermo Suarez Nelly Martínez and Geoffrey Worstey 《Vox sanguinis》1994,66(3):194-199
Thirteen infants, 10 with A-O and 3 with B-O hemolytic disease of the newborn (ABO-HDN), were treated with synthetic A or B blood group trisaccharides (ATS, BTS) which cause dissociation of maternal antibody bound to infant red cells. The clinical outcome was compared with that of a control group of 21 infants treated with phototherapy during the preceding year. Exchange transfusion was required in 2 out of 13 infants in the experimental group and in 7 in the control group. A randomized prospective controlled study is necessary to confirm these results. 相似文献
107.
Sympathetic skin response in scleroderma. 总被引:1,自引:0,他引:1
M Raszewa I Hausmanowa-Petrusewicz M B?aszczyk S Jab?ońska 《Electromyography and clinical neurophysiology》1991,31(8):467-472
Examination of the sympathetic skin response (SSR) was performed in 32 patients with systemic sclerosis, morphea and mixed connective tissue disease displaying scleroderma-like features. The control group consisted of 26 healthy subjects and 12 patients with other skin diseases and asymmetrical cutaneous changes. Right and left median and tibial nerves were stimulated successively and the responses were recorded from the palms and soles simultaneously. SSR abnormalities (delayed latency, decrease and/or asymmetry of amplitude, absent response) were observed in 68.8% of the patients, most frequently in linear scleroderma. An amplitude asymmetry of the responses from upper extremities was the most characteristic pattern of abnormalities. There was no correlation between the SSR and the localization, degree and character (inclurated oedema, atrophy, sclerosis) of skin changes, the duration of the disease, symptoms of the disorder of the autonomic nervous system symptoms (vasomotor and/or sudomotor) and the changes in capillaroscopy. All patients with slow motor conduction and sensor conduction velocities (MCV and SCV) had lower SSR amplitude and the patients with prolonged skin sensory chronaxy had more often delayed latency. The results revealed presence of disturbances of the autonomic nervous system in all varieties of scleroderma, both systemic and localized forms, even without any other signs of autonomic dysfunction. 相似文献
108.
Birol Guvenc Cagatay Unsal Emel Gurkan Abdullah Canataro?lu Bunyamin Saritas Mehtap Evran 《Transfusion and apheresis science》2004,31(1):17-20
BACKGROUND: Thrombotic thrombocytopenic purpura (TTP) is a multisystem disorder characterised by platelet aggregation causing microvascular occlusion. Early diagnosis and utilization of plasmapheresis can provide an improvement in prognosis. CASE REPORT: A 17 year old male with classical findings of TTP was later diagnosed as systemic lupus erythematosus (SLE). Plasmapheresis resulted in the significant amelioration of the course. CONCLUSION: The coexistence of TTP and SLE may facilitate a better understanding of in the pathophysiology of TTP. These association may provide the role of autoimmunity in TTP. SLE should be considered in the differential diagnosis of patients with TTP because of therapeutic implications. 相似文献
109.
110.
Aida Brand?o Sónia Magalh?es Adelino Correia 《Revista portuguesa de cardiologia》2004,23(7-8):993-999
Congenitally corrected transposition of the great arteries, L-TGA, is a rare abnormality accounting for less than 0.5% of clinically apparent congenital heart disease. Age at time of diagnosis and survival rate are variable and depend mostly on associated anomalies. The authors present a clinical case of a twenty-four-year-old woman in whom, in a routine echocardiogram, congenitally corrected transposition of the great arteries and aortic coarctation were diagnosed, an unusual association. They describe the results of complementary exams (echocardiography, chest X-ray, electrocardiogram and cardiac angiography) that they believe to be useful for the correct diagnosis of this clinical situation. Additionally, the authors make a brief review of the literature relevant to the case. 相似文献