全文获取类型
收费全文 | 36603篇 |
免费 | 2243篇 |
国内免费 | 200篇 |
专业分类
耳鼻咽喉 | 427篇 |
儿科学 | 1166篇 |
妇产科学 | 1014篇 |
基础医学 | 3704篇 |
口腔科学 | 1204篇 |
临床医学 | 3104篇 |
内科学 | 7829篇 |
皮肤病学 | 676篇 |
神经病学 | 2201篇 |
特种医学 | 1303篇 |
外国民族医学 | 4篇 |
外科学 | 6803篇 |
综合类 | 844篇 |
现状与发展 | 3篇 |
一般理论 | 27篇 |
预防医学 | 2439篇 |
眼科学 | 1340篇 |
药学 | 2834篇 |
1篇 | |
中国医学 | 264篇 |
肿瘤学 | 1859篇 |
出版年
2023年 | 359篇 |
2022年 | 487篇 |
2021年 | 1640篇 |
2020年 | 986篇 |
2019年 | 1258篇 |
2018年 | 1575篇 |
2017年 | 1141篇 |
2016年 | 1236篇 |
2015年 | 1335篇 |
2014年 | 1687篇 |
2013年 | 2059篇 |
2012年 | 3113篇 |
2011年 | 3001篇 |
2010年 | 1698篇 |
2009年 | 1473篇 |
2008年 | 2234篇 |
2007年 | 2320篇 |
2006年 | 2035篇 |
2005年 | 1814篇 |
2004年 | 1651篇 |
2003年 | 1367篇 |
2002年 | 1197篇 |
2001年 | 370篇 |
2000年 | 309篇 |
1999年 | 281篇 |
1998年 | 197篇 |
1997年 | 133篇 |
1996年 | 143篇 |
1995年 | 107篇 |
1994年 | 95篇 |
1993年 | 77篇 |
1992年 | 148篇 |
1991年 | 160篇 |
1990年 | 128篇 |
1989年 | 123篇 |
1988年 | 104篇 |
1987年 | 98篇 |
1986年 | 89篇 |
1985年 | 118篇 |
1984年 | 77篇 |
1983年 | 52篇 |
1982年 | 53篇 |
1981年 | 54篇 |
1980年 | 40篇 |
1979年 | 50篇 |
1978年 | 40篇 |
1977年 | 35篇 |
1975年 | 35篇 |
1974年 | 36篇 |
1973年 | 35篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
21.
22.
23.
To determine the protective effect of aloe-emodin (AE) from high glucose induced toxicity in RIN-5F (pancreatic β-cell) cell and restoration of its function was analyzed. RIN-5F cells have been cultured in high glucose (25 mM glucose) condition, with and without AE treatment. RIN-5F cells cultured in high glucose decreased cell viability and increased ROS levels after 48 hr compared with standard medium (5.5 mM glucose). Glucotoxicity was confirmed by significantly increased ROS production, increased pro-inflammatory (IFN-γ, IL-1β,) & decreased anti-inflammatory (IL-6&IL-10) cytokine levels, increased DNA fragmentation. In addition, we found increased Bax, caspase 3, Fadd, and Fas and significantly reduced Bcl-2 expression after 48 hr. RIN-5F treated with both high glucose and AE (20 μM) decreased ROS generation and prevent RIN-5F cell from glucotoxicity. In addition, AE treated cells cultured in high glucose were transferred to standard medium, normal responsiveness to glucose was restored within 8hr and normal basal insulin release within 24 hr was achieved when compared to high glucose. 相似文献
24.
Effects of Paclitaxel and Carboplatin Combination on Mechanical Myocardial and Microvascular Functions: A Transthoracic Doppler Echocardiography and Two‐Dimensional Strain Imaging Study 下载免费PDF全文
25.
26.
27.
Background and study aims
Acute upper gastrointestinal bleeding is one of the main causes of hospitalisation. The purpose of this study was to determine the prognostic factors in non-variceal upper gastrointestinal bleeding.Patients and methods
Clinical outcomes, demographic and laboratory variables of the subjects were collected from the HIS software and national code with the SQL format from three hospitals in Qazvin. The data were linked to the database software designed by the author. Clinical and upper endoscopic findings of patients’ records were collected through a questionnaire form in the designed software database.Results
In this study, 29.2% of patients with favourable outcome and 64.2% of patients with unfavourable clinical outcomes had a history of anticoagulant drug use before hospitalisation (p?<?0.001). The prevalence of chronic cardiovascular disease, chronic liver disease, chronic lung disease, diabetes and dialysis was higher in subjects with poor clinical outcomes than those with a favourable clinical outcome.53.1% of subjects with favourable clinical outcome and 90.5% of subjects with undesirable clinical outcomes received packed red blood cell transfusion (p?<?0.001). 16.1% of subjects with desirable clinical outcome and 86.3% of subjects with undesirable clinical outcomes received endoscopic haemostatic treatment which was statistically significant (p?<?0.001).Conclusion
Undesirable clinical outcome in patients with acute non-variceal upper gastrointestinal bleeding has a significant statistical association with longer hospitalisation, chronic underlying disease, anticoagulant administration, packed red blood cell infusion, higher Forrest stage, low systolic blood pressure, higher age, low haemoglobin, low platelet count, high INR and high BUN at the onset of diagnosis. 相似文献28.
29.
30.