全文获取类型
收费全文 | 42599篇 |
免费 | 2774篇 |
国内免费 | 434篇 |
专业分类
耳鼻咽喉 | 518篇 |
儿科学 | 1343篇 |
妇产科学 | 1096篇 |
基础医学 | 4251篇 |
口腔科学 | 1336篇 |
临床医学 | 3876篇 |
内科学 | 9019篇 |
皮肤病学 | 784篇 |
神经病学 | 2406篇 |
特种医学 | 1483篇 |
外国民族医学 | 4篇 |
外科学 | 7578篇 |
综合类 | 1617篇 |
现状与发展 | 3篇 |
一般理论 | 28篇 |
预防医学 | 2844篇 |
眼科学 | 1509篇 |
药学 | 3411篇 |
3篇 | |
中国医学 | 579篇 |
肿瘤学 | 2119篇 |
出版年
2024年 | 78篇 |
2023年 | 513篇 |
2022年 | 1281篇 |
2021年 | 1959篇 |
2020年 | 1210篇 |
2019年 | 1436篇 |
2018年 | 1767篇 |
2017年 | 1360篇 |
2016年 | 1429篇 |
2015年 | 1592篇 |
2014年 | 1999篇 |
2013年 | 2398篇 |
2012年 | 3566篇 |
2011年 | 3413篇 |
2010年 | 1998篇 |
2009年 | 1742篇 |
2008年 | 2582篇 |
2007年 | 2623篇 |
2006年 | 2304篇 |
2005年 | 2049篇 |
2004年 | 1825篇 |
2003年 | 1579篇 |
2002年 | 1344篇 |
2001年 | 463篇 |
2000年 | 390篇 |
1999年 | 335篇 |
1998年 | 220篇 |
1997年 | 156篇 |
1996年 | 157篇 |
1995年 | 124篇 |
1994年 | 115篇 |
1993年 | 92篇 |
1992年 | 151篇 |
1991年 | 170篇 |
1990年 | 135篇 |
1989年 | 127篇 |
1988年 | 109篇 |
1987年 | 104篇 |
1986年 | 89篇 |
1985年 | 122篇 |
1984年 | 79篇 |
1983年 | 54篇 |
1982年 | 57篇 |
1981年 | 55篇 |
1980年 | 41篇 |
1979年 | 51篇 |
1978年 | 40篇 |
1975年 | 35篇 |
1974年 | 38篇 |
1973年 | 37篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
81.
82.
83.
Dr. Rüçhan Ergün Ali I. Ökten Muammer Yüksel Bülent Gül Çetin Evliyaoglu Fikret Ergüngör Yamaç Taşkin 《Neurosurgical review》1997,20(1):33-37
Hydatid cysts of central nervous system are rare and comprise only 2% to 3% of all hydatid cysts reported. Orbital localization is very uncommon and has been reported less than 1 % of all hydatid diseases. The primary treatment of hydatid disease is surgical. The most important complication of the surgical treatment is secondary hydatidosis due to spillage of the cyst contents. Because of the difficulties of the orbital localization, total extirpation of the cysts without rupture is almost impossible. Preventing spontaneous rupture of the cysts during surgery and postoperative antihelmintic treatment should be taken into consideration in these cases.This study includes four cases who underwent surgery for orbital hydatid cysts. Radiological characteristics, operative technique and postoperative medical therapy are discussed. 相似文献
84.
Ali Samii Debra D Dahlen Alexander M Spence Nicole C Maronian Eric E Kraus Vanda A Lennon 《Movement disorders》2003,18(12):1556-1558
The paraneoplastic autoantibody, collapsin response-mediator protein (CRMP)-5 immunoglobulin G (IgG), is specific for neuronal cytoplasmic CRMP-5, and is usually associated with small-cell lung carcinoma or thymoma. We report on details of a movement disorder that followed anti-B-cell therapy in a patient with lymphoma, and was accompanied by CRMP-5 IgG. 相似文献
85.
【目的】探讨种植前基因诊断的临床应用。【方法】对 1例夫妇均为东南亚缺失型α 地中海贫血携带者 ,经超排取卵、卵母细胞单精子显微注射受精及胚胎细胞活检 ,吸取的单个卵裂球采用针对α SEA基因的 gap PCR引物和荧光探针用荧光定量PCR技术进行诊断 ,将诊断为不致病的 3个胚胎进行宫腔内移植。【结果】胚胎移植后 7周B超诊断单胎妊娠 ,18周羊膜腔穿刺产前诊断证实为不致病胎儿。【结论】应用成熟的显微操作技术进行胚胎细胞活检 ,活检的单个卵裂球用荧光定量PCR技术进行诊断 ,获得国内首例α 地中海贫血胚胎种植前基因诊断后妊娠成功。 相似文献
86.
Bülent Gül Sezer Kulaçoglnu Dr. Muammer Yükse Handan Dogan Ali Ihsan Ökten 《Neurosurgical review》1997,20(1):59-61
Esthesioneuroblastoma is an uncommon malignant neoplasm that arises from olfactory mucosa, often with intracranial extension.A case report of the youngest victim in the literature (2-year-old boy) is presented. 相似文献
87.
Pathological changes in testes and liver of male albino rats after dermal exposure to DDVP insecticide. 总被引:1,自引:0,他引:1
Exposure of male albino rats to DDVP insecticide at sublethal dose of 30 mg/kg/day through dermal painting for a period of 90 days didn't show any intoxication symptoms or mortality. However, cytopathological changes in testicular and liver tissues were evident. There was a positive correlation between the degree of cellular damage and the period of insecticide administration. In general, damages were prominent in rats treated for 30 days or more. Histological examination of testes showed degenerative seminiferous tubules and fewer leydig cells. Hepatic cells were congested, atrophied and showed different stages of necrobiotic changes. This suggests a great care and caution for workers during different phases of DDVP insecticide handling. 相似文献
88.
Bone scintigraphy in tuberculous sacroiliitis 总被引:1,自引:0,他引:1
Radionuclide bone imaging is becoming increasingly important in the evaluation of musculoskeletal pain of uncertain cause. A case in which Tc-99m MDP bone imaging was employed to investigate complaints of low back pain is presented. Scan abnormalities directed clinicians towards appropriate further workup and diagnosis of unilateral tuberculous sacroiliitis. 相似文献
89.
Jerrold S. Meyer Mark Grande Kenneth Johnson Syed F. Ali 《International journal of developmental neuroscience》2004,22(5-6):261
3,4-Methylenedioxymethamphetamine damages fine serotonergic fibers and nerve terminals in adult organisms. Developing animals seem to be less susceptible to this effect, possibly due to a lack of drug-induced hyperthermia. We tested this hypothesis by producing hyperthermia in neonatal rats for 2 h after each of twice-daily MDMA (10 mg/kg s.c.) or saline injections administered from postnatal days 1–4. Other drug-treated and control litters were maintained at normothermic temperatures following injection. Changes in forebrain serotonergic innervation were assessed at postnatal day 25 (serotonin transporter binding and serotonin levels), postnatal day 60 (serotonin transporter binding), and 9 months of age (serotonin transporter immunohistochemistry). We also determined the influence of MDMA treatment on apoptotic activity by means of immunohistochemistry for cleaved caspase-3 at postnatal day 5. The hippocampus showed significant MDMA-related reductions in serotonergic markers at postnatal day 25 and postnatal day 60. At 9 months, there was no effect of prior MDMA exposure on serotonin transporter-immunoreactive fiber density in the hippocampus; however, significant reductions in fiber density were observed in two neocortical areas and a hyperinnervation was found in the caudate-putamen and nucleus accumbens shell. MDMA treatment also produced a two-fold increase in the number of cleaved caspase-3-immunoreactive cells in the rostral forebrain and hippocampus. All of these effects were completely independent of pup body temperature. These findings demonstrate that neonatal MDMA administration exposure stimulates apoptotic cell death in various forebrain areas and also leads to a long-term reorganization of the forebrain serotonergic innervation. Consequently, offspring of MDMA-using women may be at heightened risk for abnormal neural and behavioral development. 相似文献
90.
Ali Ghoz Ehab Kheir Anil Kotru Karim Halazun David Kessel Jai Patel J J Peter A Lodge 《Hepatobiliary & Pancreatic Diseases International》2007,(3)
BACKGROUND:Spontaneous hemoperitoneum of hepato- biliary origin is commonly due to hemorrhage from a liver tumor.It is rarely caused by spontaneous rupture of aneurysm in visceral arteries. METHODS:We report an unusual case of hemoperitoneum caused by rupture of cystic artery pseudoaneurysm,and also outline the approach to its management through surgical and radiological methods. RESULTS:In our patient,the pseudoanurysm was initially treated with percutaneous thrombin injection.However this method of treatment failed after initial success.The pseudoanurysm was finally obliterated successfully using microcoil embolization. CONCLUSIONS:The mainstay of treatment of cystic artery pseudoaneurysm is cholecystectomy and ligation of the aneurysm.Recent publications showed success in using microcoil embolisation.In this case we also outline the use of percutaneous thrombin injection as a definitive treatment method and discuss its success or failure as a new method of treatment. 相似文献