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排序方式: 共有90条查询结果,搜索用时 15 毫秒
31.
Michalopoulou Helena Polyzos Dimitris Thomopoulos Costas Makavos George Papamikroulis George-Aggelos Nikova Alexandrina Zakynthinos George Ε. Vavouranakis Michail Siasos Gerasimos Vavouranakis Emmanouil 《Journal of thrombosis and thrombolysis》2023,55(1):92-101
Journal of Thrombosis and Thrombolysis - Patients with active cancer are at high risk of recurrent venous thromboembolism (VTE). Usual treatment includes low molecular weight heparin (LMWH), while... 相似文献
32.
The aim of this study was to test the efficiency of an extended model of the theory of planned behavior (TPB) in predicting intention to improve oral health behaviors. The participants in this cross-sectional study were 153 first-year medical students (mean age 20.16, 50 males and 103 females) who completed a questionnaire assessing intentions, attitudes, subjective norms, perceived behavioral control, oral health knowledge, and current oral hygiene behaviors. Attitudes toward oral health behaviors and perceived behavioral control contributed to the model for predicting intention, whereas subjective norms did not. Attitudes toward oral health behaviors were slightly more important than perceived behavioral control in predicting intention. Oral health knowledge significantly affected affective and cognitive attitudes, while current behavior was not a significant predictor of intention to improve oral health behavior. The model had a slightly better fit among females than among males, but was similar for home and professional dental health care. Our findings revealed that attitude, perceived behavioral control, and oral health knowledge are predictors of intention to improve oral health behaviors. These findings may help both dentists and dental hygienists in educating patients in oral health and changing patients' oral hygiene habits. 相似文献
33.
Throckmorton AL Untaroiu A 《ASAIO journal (American Society for Artificial Internal Organs : 1992)》2008,54(4):423-431
Thousands of pediatric patients suffering from heart failure would benefit from longer-term mechanical circulatory support. There are, however, few support systems available in the United States as viable mechanical assist alternatives for these patients. Therefore, we have designed and developed an axial flow pediatric ventricular assist device (PVAD) with an impeller that is fully suspended by magnetic bearings. This blood pump is designed to generate 0.5-4 L/min for pressure rises of 50-95 mm Hg over 6,000-9,000 rpm. We have performed four major design iterations. Building upon the third design phase, we made improvements to create the PVAD4 model. Numerical simulations of the PVAD4 under steady flow simulations were performed to compare the predictions of the latest PVAD4 model to the earlier PVAD3 design. The PVAD4 design resulted in lower fluid stress levels and an increase in pressure generation. A blood damage analysis was also completed. As compared with the earlier PVAD3 design, the damage analysis of the PVAD4 indicated a reduction in the mean and maximum damage index for the new design. All of these numerical findings are encouraging and demonstrate progress toward achieving a superior pump design. 相似文献
34.
Desislava Kostova-Lefterova Mariela Vasileva-Slaveva Svilen Maslyankov Assia Konsoulova Margarita Atanasova Tsvetelina Paycheva Alexandrina Vlahova Marusya Genadieva-Yordanova Ginka Prodanova Zahari Zahariev Vasil Pavlov Georgi Todorov Boris Vasilev Kostadin Angelov Tashko Deliyski Ivelina Petrova Desislava Hitova Ivo Petrov 《Current oncology (Toronto, Ont.)》2021,28(5):3932
(1) Background: We aimed to analyze currently available studies with intraoperative radiotherapy (IORT) as a choice of treatment where the Xoft Axxent® electronic brachytherapy (eBx) system was used as a single-dose irradiation and an exclusive radiotherapy approach at the time of surgery in patients with early breast cancer (EBC). We also compared the results of the systematic review to the Bulgarian experience. (2) Methods and Materials: We performed a systematic review of the studies published before February 2021, which investigate the application of a single-fraction 20 Gy radiation treatment, delivered at the time of lumpectomy in EBC patients with the Xoft Axxent® eBx System. A systematic search in PubMed, Scopus, and ScienceDirect was performed. The results are reported following the PRISMA guidelines. The criteria on patients’ selection for IORT (the additional need for EBRT), cosmetic outcomes, and recurrence rate from the eligible studies are compared to the treatment results in Bulgarian patients. (3) Results: We searched through 1032 results to find 17 eligible studies. There are no published outcomes from randomized trials. When reported, the cosmetic outcomes in most of the studies are defined as excellent. The observed recurrence rate is low (1–5.8%). Still, the number of patients additionally referred to postoperative external breast radiotherapy (EBRT) is up to 31%. Amongst the 20 patients treated in Bulgaria, the cosmetic outcomes are also evaluated as excellent, five of which (25%) are referred for EBRT. Within median follow-up of 39 months, there was one local and one distal recurrence. (4) Conclusions: Current evidence demonstrates the Xoft Axxent® eBx system as a safe and feasible technique for IORT delivery in EBC patients. There are no randomized controlled trials conducted at this time point to prove its long-term effectiveness. Better patient selection and a reimbursement strategy have to be proposed to extend the application of this technique in Bulgaria. 相似文献
35.
Alexandrina Muntean Codruta Sarosi Sorina Sava Marioara Moldovan Andrei Ilie Condurache Ada Gabriela Delean 《Materials》2021,14(7)
Tooth decay in children and adolescents remains a public health problem, despite prophylaxis and preventive measures being largely available. The aim of our study was to evaluate the clinical behavior of four dental sealants, related to first permanent molar topography and patient age (when sealant was applied for the first time). We assessed, by means of visual inspection and palpation with a dental probe, a group of 200 children, enrolled corresponding to school age-grade (mean age of 7 years at baseline) and randomly divided according to the material used as dental sealant (Admira seal©, Embrace Wet Bond©, Fotoseal©, GC Fuji Triaje©) in 4 groups (n = 50). Sealant clinical evaluation was made at 6-, 12-, 18-month intervals for dental material retention assessment. At 6 months, the sealant detached the most from 3.6 molars, and the material used was Fotoseal© (27.6%). At 12 months, Fotoseal© (48.3%) and GC Fuji Triaje© (41.4%) from 3.6 molars express detachment. At 18 months, 4.6. molars sealed with Admira Seal© (25.7%) and Embrace Wet Bond© (28.6%) lost the sealant. We noticed less detachment in maxillary molars and if sealant was applied around 7 years of age. In conclusion, sealant application on first permanent molars must be encouraged and practitioners can choose between various materials available. 相似文献
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38.
Véronique Loustaud-Ratti Paul Carrier Annick Rousseau Marianne Maynard Gérard Babany Sophie Alain Christian Trépo Victor De Ledinghen Marc Bourlière Stanislas Pol Vincent Di Martino Jean-Pierre Zarski Alexandrina Pinta Denis Sautereau Pierre Marquet the OPTIRIB group 《Digestive and liver disease》2011,43(11):850-855
Ribavirin remains today a pivotal drug in the treatment of hepatitis C; in standard double therapy, as well as in triple combination with direct antiviral agents, ribavirin reduces relapse and can double the sustained virological response obtained with peginterferon alone or in association with direct antiviral agents. In the complex network of interacting factors determining sustained virological response independently of known predictive factors related to host and virus, two modern tools are emerging: polymorphisms in the IL28B gene and very early exposure to ribavirin. The use of a pharmacokinetic–pharmacodynamic model of early ribavirin exposure to adjust the dose individually would help promote a safer ribavirin use and improve sustained virological response. The variability of the influence of ribavirin exposure on anaemia is probably genetically determined; however, the low prevalence of the implicated protective alleles of the inosine triphosphate pyrophosphatase gene could explain their lack of influence on sustained virological response. 相似文献
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40.
Non-compaction of the ventricular myocardium is a cardiomyopathy caused by the arrest of normal embryogenesis of the ventricles. It is classified in isolated non-compaction of the ventricles (most frequently of the left one) and in ventricular non-compaction associated with other congenital anomalies of the endocardium and myocardium, such as obstruction of the right or left ventricular outflow tracts, complex cyanotic congenital heart disease, and coronary artery anomalies. There are controversies regarding the right ventricle non-compaction due to the normally trabeculated shape of its walls.We present a case of severe heart failure with a complex anomaly: biventricular non-compaction, ventricular septal defect and aortic thoracic stenosis. 相似文献