全文获取类型
收费全文 | 1424篇 |
免费 | 57篇 |
国内免费 | 4篇 |
专业分类
耳鼻咽喉 | 20篇 |
儿科学 | 23篇 |
妇产科学 | 20篇 |
基础医学 | 149篇 |
口腔科学 | 29篇 |
临床医学 | 75篇 |
内科学 | 483篇 |
皮肤病学 | 78篇 |
神经病学 | 142篇 |
特种医学 | 18篇 |
外科学 | 178篇 |
综合类 | 8篇 |
一般理论 | 1篇 |
预防医学 | 85篇 |
眼科学 | 13篇 |
药学 | 76篇 |
肿瘤学 | 87篇 |
出版年
2024年 | 1篇 |
2023年 | 13篇 |
2022年 | 4篇 |
2021年 | 30篇 |
2020年 | 12篇 |
2019年 | 43篇 |
2018年 | 49篇 |
2017年 | 22篇 |
2016年 | 23篇 |
2015年 | 34篇 |
2014年 | 35篇 |
2013年 | 59篇 |
2012年 | 137篇 |
2011年 | 119篇 |
2010年 | 77篇 |
2009年 | 48篇 |
2008年 | 108篇 |
2007年 | 100篇 |
2006年 | 98篇 |
2005年 | 101篇 |
2004年 | 94篇 |
2003年 | 86篇 |
2002年 | 78篇 |
2001年 | 30篇 |
2000年 | 20篇 |
1999年 | 16篇 |
1998年 | 6篇 |
1997年 | 3篇 |
1996年 | 3篇 |
1995年 | 2篇 |
1994年 | 2篇 |
1993年 | 2篇 |
1992年 | 3篇 |
1991年 | 2篇 |
1990年 | 4篇 |
1989年 | 6篇 |
1988年 | 4篇 |
1987年 | 3篇 |
1986年 | 1篇 |
1985年 | 2篇 |
1984年 | 1篇 |
1983年 | 2篇 |
1971年 | 1篇 |
1969年 | 1篇 |
排序方式: 共有1485条查询结果,搜索用时 93 毫秒
51.
Pilar Cidad Eduardo Miguel-Velado Christian Ruiz-McDavitt Esperanza Alonso Laura Jiménez-Pérez Agustín Asuaje Yamila Carmona Daniel García-Arribas Javier López Yngrid Marroquín Mirella Fernández Mercè Roqué M. Teresa Pérez-García José Ramón López-López 《Pflügers Archiv : European journal of physiology》2015,467(8):1711-1722
52.
Santiago Gascon Michael P Leiter Eva Andrés Miguel A Santed Joao P Pereira María J Cunha Agustín Albesa Jesus Montero‐Marín Javier García‐Campayo Begoña Martínez‐Jarreta 《Journal of clinical nursing》2013,22(21-22):3120-3129
Aims and objectives. To examine the prevalence of aggression against healthcare professionals and to determine the possible impact that violent episodes have on healthcare professionals in terms of loss of enthusiasm and involvement towards work. The objective was to analyse the percentage of occupational assault against professionals’ aggression in different types of healthcare services, differentiating between physical and verbal aggression as a possible variable in detecting burnout in doctors and nursing professionals. Background. Leiter and Maslach have explored a double process model of burnout not only based on exhaustion by overload, but also based on personal and organisational value conflicts (community, rewards or values). Moreover, Whittington has obtained conclusive results about the possible relationship between violence and burnout in mental health nurses. Design. A retrospective study was performed in three hospitals and 22 primary care centres in Spain (n = 1·826). Methods. Through different questionnaires, we have explored the relationship between aggression suffered by healthcare workers and burnout. Results. Eleven percent of respondents had been physically assaulted on at least one occasion, whilst 34·4% had suffered threats and intimidation on at least one occasion and 36·6% had been subjected to insults. Both forms of violence, physical and non‐physical aggression, showed significant correlations with symptoms of burnout (emotional exhaustion, depersonalisation and inefficacy). Conclusions. The survey showed evidence of a double process: (1) by which excess workload helps predict burnout, and (2) by which a mismatch in the congruence of values, or interpersonal conflict, contributes in a meaningful way to each of the dimensions of burnout, adding overhead to the process of exhaustion–cynicism–lack of realisation. Relevance to clinical practice. Studies indicate that health professionals are some of the most exposed to disorders steaming from psychosocial risks and a high comorbidity: anxiety, depression, etc. There is a clear need for accurate instruments of evaluation to detect not only the burnout but also the areas that cause it. Professional exhaustion caused by aggression or other factors can reflect a deterioration in the healthcare relationship. 相似文献
53.
54.
Bovine viral diarrhea virus structural protein E2 as a complement regulatory protein 总被引:1,自引:0,他引:1
Agustín Ostachuk 《Archives of virology》2016,161(7):1769-1782
55.
56.
Juan Violante-González Ma. Leopoldina Aguirre-Macedo Agustín Rojas-Herrera Salvador Gil Guerrero 《Parasitology research》2009,105(4):997-1005
The seasonal dynamic of the metazoan parasite community of the blue sea catfish (Sciades guatemalensis) from Tres Palos Lagoon, Guerrero, Mexico, was studied at the component community and infracommunity levels. A total of 382
fish were collected during the regional dry and rainy seasons (a total of seven seasons) between April 2000 and September
2007. Nine helminths were collected: Neotetraonchus sp., Pseudoacanthostomum panamense, Austrodiplostomum compactum, Clinostomum complanatum, Metadena sp., Pseudoleptorhynchoides lamothei, Neoechinorhynchus cf. golvani, Hysterothylacium perezi, and Contracaecum sp. The infection dynamics of some dominant helminths was influenced by environmental changes generated by the dry/rainy
season cycle. Nested (non-random) species composition was observed in the infracommunities during almost all of the sample
period. Variation in the intensity of nestedness was attributed to a sequential colonization process over time by the dominant
helminths. 相似文献
57.
Enrique Marco de Lucas Andrés González Mandly Agustín Gutiérrez Raúl Pellón Laura Martín-Cuesta Javier Izquierdo Elena Sánchez Eva Ruiz Fernando Quintana 《Clinical rheumatology》2009,28(3):315-320
Computed tomography (CT)-guided biopsy of the spine is considered a safe, accurate, and relatively inexpensive examination
technique. Our purpose was to determine the diagnostic accuracy of CT-guided biopsies exclusively for vertebral osteomyelitis.
A retrospective study was performed from a consecutive series of 72 patients with confirmed vertebral osteomyelitis with 46
CT-guided biopsies performed in 40 patients. Biopsy specimens were sent for bacteriologic and cytologic analysis. An adequate
specimen for microbiologic examination was not obtained in one case and not enough sample for additional pathologic examination
in 17 cases. The mean age of patients was 58 years, with a range of 1–88 years, including 24 men and 16 women. The level of
spinal biopsy was thoracic in 18 (40%) and lumbar in 28 (60%). The analysis revealed the infection agent in 20 cases (43%
sensitivity). Diagnostic rates obtained in patients with previous antibiotic treatment were significantly lower (23% vs. 60%,
p = 0.013). Computed tomography-guided fine-needle aspiration biopsy is an important tool in the diagnostic evaluation of vertebral
osteomyelitis. However, this technique yields a lower diagnostic rate than previously reported biopsy of neoplastic vertebral
lesions, especially if performed in patients with previous antibiotic treatment. 相似文献
58.
BACKGROUND: Older adults throughout the developed world are at significant risk of osteoporotic fractures. Many studies have examined the relationship between the use of psychotropic medications and the risk of fractures, but these studies have reported conflicting results. PURPOSE: To resolve discrepancies, we carried out a meta-analysis to assess the risk of fractures among users of several classes of psychotropic drugs. DATA SOURCES: We retrieved studies published in any language by systematically searching MEDLINE, LILACS, EMBASE and ISI Proceedings databases and by manually examining the bibliographies of the articles retrieved electronically as well as those of recent reviews. STUDY SELECTION: We included 98 cohort and case-control studies, published in 46 different articles, that reported relative risk (RR) estimates and confidence intervals (CIs) or sufficient data to calculate these values. DATA SYNTHESIS: Study-specific RRs were weighted by the inverse of their variance to obtain fixed- and random effects pooled estimates. The random effects RR of fractures was 1.34 (95% CI 1.24, 1.45) for benzodiazepines (23 studies), 1.60 (95% CI 1.38, 1.86) for antidepressants (16 studies), 1.54 (95% CI 1.24, 1.93) for non-barbiturate antiepileptic drugs (13 studies), 2.17 (95% CI 1.35, 3.50) for barbiturate antiepileptic drugs (five studies), 1.59 (1.27, 1.98) for antipsychotics (12 studies), 1.15 (95% CI 0.94, 1.39) for hypnotics (13 studies) and 1.38 (95% CI 1.15, 1.66) for opioids (six studies). For non-specified psychotropic drugs (10 studies), the pooled RR was 1.48 (95% CI 1.41, 1.59). LIMITATIONS: Main concerns were the potential for residual confounding and for publication bias. CONCLUSION: Globally, the increase in the risk of fractures among psychotropic drug users is moderate. Further research is needed, especially to examine high-risk populations and newer medications. Future studies should be prospective and emphasise control of confounding bias. 相似文献
59.
BACKGROUND: The high degree to which systemic antibiotics are consumed in our country makes a study of those factors determining the spread thereof necessary. Different parameters are involved in the unequal spread of their consumption, including: a) the epidemiology of the infectious processes b) the population-dependent factors and c) factors depending upon the prescribing physicians. This study is aimed at analyzing those determining factors depending upon the population (type of population and age). METHODS: A longitudinal retrospective study based on systemic antibiotic consumption data provided by the company International Marketing Services (IMS) for the January 1, 1996-December 31, 2000 period. The consumption indicator used was the number of daily doses defined per 1000 inhabitants/day (DID). Six geographical areas in the province of Valladolid were placed under study, three of which were urban and the other three mainly rural. RESULTS: The overall consumption by area was as follows: Medina del Campo (25.9DID), the capital city of Valladolid (23.4DID), Laguna de Duero (22.6DID), Northern Area (22.4DID), Southern Area (21.4DID) and, lastly, the Central Area (20.2DID). The specific consumption by areas revealed a greater consumption of amoxicillin in the three urban areas, amoxicillin-clavulanic acid and the major macrolides in Medina del Campo, quinolone antibiotics in the Northern Area and tetracyclines and sulfonamides in the capital city of Valladolid. CONCLUSIONS: Major overall consumption-related differences were found to exist among areas, the maximums being found in the urban areas. These differences were more marked on when studying the geographic spread of the consumption of the main active ingredients. 相似文献
60.