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121.
Agustín Malón 《Archives of sexual behavior》2010,39(3):637-652
For some decades now in the West, there has been a growing social anxiety with regard to a phenomenon which has become known
as child sexual abuse (CSA). This anxiety is fed by scientific theories whose cornerstone is the assessment of these experiences
as necessarily harmful, due to their presumed serious consequences for the present and future lives of the minors involved
in them. This principle, widely held by experts and laypersons alike, was also part and parcel of the danger presumably posed
by Onanism, a phenomenon which occupied a similar position in society and medical science in the West during the eighteenth
through twentieth centuries. The present work is a comparative review of these two hypotheses and the central objective was
to compare the evolution and fundamental elements of the two hypotheses in light of what history tells us about Onanism theory.
This comparative analysis will allow a critical look at the assumptions of the CSA hypothesis in order to make evident the
similarities to the conceptual model that enabled the Onanism hypothesis in the past. 相似文献
122.
Luis Chiva de Agustín Fernando Lapuente Sastre Virginia Corraliza Galán Luis Granados Galainena Antonio González Martín Lucía González Cortijo Natalia Carballo González 《Clinical & translational oncology》2008,10(3):155-162
Objective To know the characteristics of endometrial adenocarcinoma in young patients and to review the published experience in patients
with endometrial adenocarcinoma that were conservatively managed with hormonal therapy to spare their fertility.
Methods We carried out a search in the Survey conducted by the Section of Oncologic Gynecology of SEGO (Spanish Society of Gynecologists)
to identify the characteristics of young patients with endometrial adenocarcinoma. In addition we searched MEDLINE and other
databases for English-language articles describing patients with endometrial adenocarcinoma who were treated with hormonal
therapy. The search included articles published between January 1966 and January 2007.
Results Endometrial carcinoma in patients under 45 years old is an unusual condition that shows a more favourable pattern than in
older patients. One hundred and thirty-three patients were found in the search. The average duration of hormonal therapy was
approximately six months. The average response time was 12 weeks; 76% of patients treated with hormonal therapy had a complete
response and the other 24% never responded to treatment. Of those who initially responded, 66% percent did not show recurrence
of disease. The other 34% had a relapse. There have been 4 published deaths of conservatively managed patients.
Conclusion A conservative approach in these patients can offer reasonable oncological security and the opportunity of fulfilling their
maternal desires in selected cases. However, consideration should be taken regarding the potential adverse outcomes that have
been recently published in the literature. 相似文献
123.
Bronchoalveolar lavage analysis with anti-T6 monoclonal antibody in the evaluation of diffuse lung diseases 总被引:1,自引:0,他引:1
A Xaubet C Agustí C Picado S Gueréquiz J A Martos M Carrión A Agustí-Vidal 《Respiration; international review of thoracic diseases》1989,56(3-4):161-166
To evaluate the usefulness of anti-T6 monoclonal antibody cell analysis in the assessment of diffuse lung disease, 77 bronchoalveolar lavages (BAL) were performed on 70 subjects: 18 normal smokers, 14 normal nonsmokers, 30 patients with chronic interstitial lung diseases (15 sarcoidosis, 12 idiopathic or associated pulmonary fibrosis, 3 histiocytosis X) and 8 patients with diffuse lung neoplastic disorders. The percentage of T6-positive cells was significantly higher in normal smokers than in normal nonsmokers (p less than 0.05). Positive T6 cells were absent or less than 1% in normal subjects, in patients with interstitial lung diseases and in patients with diffuse lung cancer, except in a case of desquamative interstitial pneumonitis, who had 2% of reacting cells. In contrast, such cells were always 3% or higher in the 6 BAL performed in histiocytosis X patients (p less than 0.05). 相似文献
124.
E Sala L Alegre M Carrera M Ibars F J Orriols M L Blanco F Cárceles S Bertran F Mata I Font A G Agustí 《The European respiratory journal》2001,17(6):1138-1142
This prospective, controlled, but not formally randomized study investigates the feasibility and efficiency of an alternative to standard hospitalization for patients with exacerbated chronic obstructive pulmonary disease (COPD), based upon supported discharge with nurse supervision at home. Over a 12-month period, emergency physicians, not directly involved in the study, admitted 205 patients with exacerbated COPD to the authors' respiratory unit. Patients were included in the supported discharge group (n=105) if they voluntarily chose to participate in the programme and lived in the city of Palma de Mallorca (where adequate home support could be provided). Patients not fulfilling these criteria (mainly residents outside the city) served as controls (n=100). Inpatient treatment was standardized in all patients and included oxygen therapy, bronchodilators, antibiotics and steroids. Both groups were comparable in terms of age (mean +/- SD: 70 +/- 10 versus 65 +/- 11 yr for supported discharge and control group, respectively), severity of airflow obstruction (forced expiratory volume in one second 45 +/- 18% reference versus 46 +/- 19% ref.), comorbidity and socioeconomic status. Length of hospital stay (LOS) in the supported discharge group was shorter (5.9 +/- 2.8 versus 8.0 +/- 5.1 days, p < 0.001). After discharge, a respiratory nurse visited supported discharge patients at home during 7.3 +/- 3.8 days. Only one patient (1%) required hospital readmission during this period of time. The reduced LOS resulted in a lower utilization of hospital beds at any given point in time throughout the study period. Within the framework and potential limitations of this study, the results indicate that the supported discharge programme in Spain: 1) allows a significant reduction in the length of hospital stay of patients hospitalized because of an exacerbation of chronic obstructive pulmonary disease; 2) does not result in an inappropriately increased rate of hospital readmissions; and 3) reduces the utilization of hospital resources. 相似文献
125.
Agustín Buendía Eisman José Eduardo Muñoz Negro María Claudia Palau Lázaro Salvio Serrano Ortega 《Piel》2009,24(1):12-16
The existence of factors associated with sun protection could help researchers to identify the features of sun protection behavior in detail. To approach the subject, we performed a search in Pubmed and the Spanish Medical Index of articles that included the pediatric age group published between 1986 and 2006. 相似文献
126.
Mónica Pérez-Ríos Juan M Barros-Dios Agustín Montes-Martínez Alberto Ruano-Ravina 《BMC public health》2010,10(1):256
Background
Radon is the second risk factor for lung cancer after tobacco consumption and therefore it is necessary to know the burden of disease due to its exposure. The objective of this study is to estimate radon-attributable lung cancer mortality in Galicia, a high emission area located at the Northwest Spain. 相似文献127.
César P. Ramírez Plaza Manuel A. Cobo Dols Alberto Gómez Portilla Agustín de la Fuente Perucho 《Clinical & translational oncology》2005,7(10):421-431
The median survival in patients with peritoneal carcinomatosis from colorectal adenocarcinoma is, with conventional approaches,
only about six months. Combined treatment consisting of maximum cytoreductive surgery plus intraoperative intraperitoneal
hyperthermic chemotherapy has been shown, albeit in small non-comparative series, to increase disease-free survival and overall
survival, compared with previous series. Further, a randomized trial has demonstrated better results (a median survival of
22.4 months) with cytoreduction plus intraperitoneal chemotherapy compared with conventional chemotherapy. Technical considerations,
infrastructure requirements and possible complications imply specialized centres and staff. Surgery consists of peritonectomy
of affected areas and fulguration of all macroscopic lesions. Intraperitoneal chemotherapy must reach all parts of the peritoneal
cavity and the temperature of the hyperthermic procedure must be maintained between 42–44°C. Three prognostic factors associated
with this procedure are: pathologic tumour grade, peritoneal carcinomatosis index, and cytoreductive surgery grade. 相似文献
128.
Raul A. Bastarrachea MD Juan C. López-Alvarenga MD PhD Raúl Calzada-León MD Sara Arellano-Montaño MD Jorge Gonzalez-Barranco MD Rafael Violante-Ortíz MD Blanca Estela Del-Rio-Navarro MD Agustín Lara-Esqueda MD Pedro Pérez MD Guillermo Fanghänel MD Agustín Madero MD Arturo Berber MD PhD 《Advances in therapy》2006,23(3):506-509
129.
130.