全文获取类型
收费全文 | 11227篇 |
免费 | 671篇 |
国内免费 | 82篇 |
专业分类
耳鼻咽喉 | 81篇 |
儿科学 | 286篇 |
妇产科学 | 179篇 |
基础医学 | 1124篇 |
口腔科学 | 154篇 |
临床医学 | 1175篇 |
内科学 | 2807篇 |
皮肤病学 | 176篇 |
神经病学 | 747篇 |
特种医学 | 295篇 |
外国民族医学 | 1篇 |
外科学 | 2097篇 |
综合类 | 288篇 |
现状与发展 | 1篇 |
一般理论 | 6篇 |
预防医学 | 633篇 |
眼科学 | 240篇 |
药学 | 955篇 |
中国医学 | 160篇 |
肿瘤学 | 575篇 |
出版年
2024年 | 15篇 |
2023年 | 152篇 |
2022年 | 450篇 |
2021年 | 741篇 |
2020年 | 450篇 |
2019年 | 573篇 |
2018年 | 580篇 |
2017年 | 356篇 |
2016年 | 397篇 |
2015年 | 437篇 |
2014年 | 547篇 |
2013年 | 649篇 |
2012年 | 993篇 |
2011年 | 947篇 |
2010年 | 457篇 |
2009年 | 435篇 |
2008年 | 648篇 |
2007年 | 634篇 |
2006年 | 538篇 |
2005年 | 535篇 |
2004年 | 416篇 |
2003年 | 407篇 |
2002年 | 243篇 |
2001年 | 59篇 |
2000年 | 41篇 |
1999年 | 35篇 |
1998年 | 36篇 |
1997年 | 17篇 |
1996年 | 16篇 |
1995年 | 12篇 |
1994年 | 12篇 |
1993年 | 15篇 |
1992年 | 13篇 |
1991年 | 9篇 |
1990年 | 6篇 |
1989年 | 8篇 |
1988年 | 10篇 |
1987年 | 5篇 |
1985年 | 8篇 |
1984年 | 8篇 |
1983年 | 5篇 |
1982年 | 7篇 |
1981年 | 15篇 |
1980年 | 7篇 |
1979年 | 5篇 |
1978年 | 6篇 |
1977年 | 3篇 |
1976年 | 4篇 |
1975年 | 3篇 |
1972年 | 7篇 |
排序方式: 共有10000条查询结果,搜索用时 62 毫秒
41.
Wang BY Boag AH Idrees M Young ID Unger PD 《Archives of pathology & laboratory medicine》2004,128(4):456-459
Pathologic processes involving the urachus are usually related to inflammatory or sinofistular conditions. Neoplasms rarely arise within this structure, and when they do occur, they are typically epithelial, with mucinous adenocarcinoma being the most common. Mesenchymal lesions, both benign and malignant, have rarely been described in this location. We report the case of a 66-year-old white man who presented with a primary urachal malignant fibrous histiocytoma and died of metastatic disease 20 months after the initial diagnosis. This is an unusual case of malignant fibrous histiocytoma arising in a urachal remnant. 相似文献
42.
K Tokiyoshi T Yoshimine M Maruno A K M G Muhammad T Hayakawa 《Journal of clinical pathology》1996,49(4):M218-M222
Aims—To elucidate the implications of allelic loss on chromosome 10 in the malignant progression of human gliomas. 相似文献
43.
Muhammad Novrizal Abdi Sahid Takeshi Kiyoi 《Journal of immunoassay & immunochemistry》2020,41(4):778-816
ABSTRACT Mast cells (MCs) are well known for their role in allergic conditions. This cell can be activated by various types of secretagogues, ranging from a small chemical to a huge protein. Mast cell activation by secretagogues triggers the increase in intracellular calcium (iCa2+) concentration, granule trafficking, and exocytosis. Activated mast cells release their intra-granular pre-stored mediator or the newly synthesized mediator in the exocytosis process, in the form of degranulation or secretion. There are at least three types of exocytosis in mast cells, which are suggested to contribute to the release of different mediators, i.e.,, piecemeal, kiss-and-run, and compound exocytosis. The status of mast cells, i.e., activated or resting, is often determined by measuring the concentration of the released mediator such as histamine or β-hexosaminidase. This review summarizes several mast cell components that have been and are generally used as mast cell activation indicator, from the classical histamine and β-hexosaminidase measurement, to eicosanoid and granule trafficking observation. Basic principle of the component determination is also explained with their specified research application and purpose. The information will help to predict the experiment results with a certain study design. 相似文献
44.
Marieke C. J. Dekker Adnan M. Sadiq Mubashir A. Jusabani Vivian J. Mdavire Frank Baas David H. Morton Ben C. J. Hamel 《American journal of medical genetics. Part A》2019,179(10):2034-2038
We report an African infant with Ellis‐van Creveld (EVC) syndrome. EVC syndrome is a chondral and ectodermal dysplasia with autosomal recessive transmission. The baby presented with polydactyly, short limbs and atrioventricular septal defect, but was withdrawn from clinical follow up for the first year of life. Initial hematological abnormalities could not be explained and normalized later. EVC syndrome was confirmed by genetic analysis that showed two pathogenic mutations in the EVC2 gene, c.653_654del, p.Val218Glyfs*12 in exon 5, and c.2710C>T, p.Gln904* in exon 16. The variant c.653_654del; p.Val218Glyfs*12 in exon 5 has not been described before. Our review of medical literature suggested this is the first molecularly confirmed case of EVC syndrome in sub‐Saharan Africa. 相似文献
45.
Ito Y Tanaka N Fujimoto Y Yasunaga Y Ishida O Agung M Ochi M 《Journal of biomedical materials research. Part A》2004,69(3):454-461
The clinical use of cultured marrow stromal stem cells (MSCs) has recently attracted attention in the field of tissue engineering. For the clinical use of the MSCs, a prominent scaffold is needed. A scaffold hybridized with MSCs is transformed into a "bioactive bone substitute," and this provides good osteoconduction. In this study, a novel calcium hydroxyapatite ceramic with an interconnected porous structure (IP-CHA) was used as a scaffold. MSCs were harvested from Green rats containing Green Fluorescent Protein (GFP), and then these hybrids were implanted into the tibias of Sprague-Dawley rats. The purposes of this study were to examine the osteogenic ability of these hybrids without coculture, and to evaluate whether the resulting bone formation originated from the grafted MSCs or the recipient's cells. The hybridized group showed excellent bone formation compared with the IP-CHA-only implant group. Observation of the implanted MSCs revealed that they survived 8 weeks after surgery, and differentiated into osteoblast-like cells, thus providing bone formation. This implantation of the MSCs/IP-CHA composite provides excellent osteoconduction, and is expected to have extensive clinical applications. 相似文献
46.
47.
Wajid M Abbasi AA Ansar M Pham TL Yan K Haque S Ahmad W Leal SM 《European journal of human genetics : EJHG》2003,11(10):812-815
This article describes the identification of a novel locus (DFNB39) responsible for an autosomal recessive form of hearing loss segregating in a Pakistani consanguineous family. The hearing impaired members of this family present with profound prelingual sensorineural hearing impairment and use sign language for communications. Linkage was established to microsatellite markers located on chromosome 7q with a maximum multipoint lod score of 3.8. The region of homozygosity spans a 19 cM region that is bounded by markers D7S3046 and D7S644. 相似文献
48.
49.
50.
Elias N. Nasr Muhammad A. K. Bhatti Errol Warner 《Journal of the National Medical Association》1981,73(6):525-529
Five cases of duodenal injuries were treated in our hospital between January 1, 1975 and June 18, 1979. They belonged to the Class II and early Class III of duodenal injuries. They were treated with simple closure of the perforation in a single or double layer with external drainage. Only in one case were gastrojejunostomy and bilateral vagotomy added because the patient had a history of ulcer disease. The delay in operative treatment ranged between five and 48 hours. All responded well to the surgical treatment. In the instance of the longest operative delay, a purulent drainage occurred and it responded promptly to a selective antibiotic therapy. The average hospitalization stay was nine days for the patients operated upon early, whereas it was 15 days for the two delayed cases. No mortality was recorded. 相似文献