Photogrammetry-Based Volume Measurement Framework for the Particle Density Estimation of LECA

This paper presents a photogrammetry-based volume measurement framework for the particle density estimation of Lightweight expanded clay aggregate (LECA). The results are compared with computed tomography (CT) and Archimedes’ method measurements. All of the steps required in order to apply the proposed approach are explained. Next, we discuss how the interpretation of open pores affects the results of volume measurements. We propose to process the shapes obtained from different methods by applying an Ambient Occlusion algorithm with the same threshold, t = 0.175. The difference between the CT and SfM methods is less than 0.006 g/cm³, proving that the photogrammetry-based approach is accurate enough. The Archimedes’ method significantly overestimates the density of the particles. Nevertheless, its accuracy is acceptable for most engineering purposes. Additionally, we evaluate the accuracy of shape reconstruction (in terms of the Hausdorff distance). For 95% of the grain’s surface, the maximum error is between 0.073 mm and 0.129 mm (depending on the grain shape). The presented approach is helpful for measuring the particle density of porous aggregates. The proposed methodology can be utilized in order to estimate intergranular porosity, which is valuable information for the calibration of DEM models.     

Response to Dr. Nicholas Foray’s commentary on the paper by Rousseau et al. entitled “Efficacy of intracerebral delivery of cisplatin in combination with photon irradiation for treatment of brain tumors”

Journal of Neuro-Oncology -     

A review of Kallmann syndrome: genetics, pathophysiology, and clinical management

Kallmann syndrome is a genetic disorder with the hallmarks of anosmia and hypogonadotrophic hypogonadism. It has a male preponderance. With the elucidation of the genetic pathways involved, affected females and inheritance patterns are becoming more clearly identified. It is an eminently treatable disorder, but it must first be recognized by the physician. With treatment, favorable reproductive outcomes can be attained in addition to maturation of secondary sex characteristics.