Osteoporosis and vertebral collapse following low-dose,low molecular weight heparin therapy in a young patient

Osteoporosis is a well-recognized complication of long-term heparin (unfractionated) therapy. It has been suggested that the low molecular weight heparins (LMWH) have a lower potential to cause osteopenia than the unfractionated preparations. We report a case of a 29-year-old woman who developed osteoporosis and pathological fracture of lumbar vertebrae following treatment with low dose LMWH (dalteparin) for 3 months. The aim of this report is to alert clinicians to the potential risk of this complication with the prolonged use of LMWH preparations — an increasingly popular choice for long-term anticoagulation.     

Presence of Specific Receptor Binding Sites for Inhibin in Rat Spermatids

Vorhandensein von spezifischen Rezeptorbindungs-Plätzen für Inhibin in Ratten-Spermatiden
In Rattenspermatiden konnten hohe Werte für Inhibin der Anwesenheit einer hohen Affinitäts-Klasse von Inhibin-Rezeptoren zugeschrieben werden. Die in vitro-Inkorporation von ³H-Leucin an immunopraezipitables Inhibin weist darauf hin, daß die Biosynthese von Inhibin in den Spermatocyten erfolgt. Für eine Synthese von Inhibin durch die Spermatiden ergab sich keinerlei Beweis.