福建省龙岩市碘缺乏病病情监测结果分析

Objective To understand the current situation of iodine deficiency diserders(IDD) in Longyan City and to evaluate the effect of prevention and control measures of IDD in order to provide evidence for formulating prevention and control tactics. Methods During the year of 2006 and 2007, the 30 primary schools were screened by population proportion survey(PPS) from the 7 counties of Longyan City. Forty children aged 8-10 years in each school were randomly selected as a group to examine thyroid, and 7 children in each group were selected to measure the urine iodine and the salt iodine at the same time. The goiter rote, the median urinary iodine, the consumption rate of qualified iodized salt, the iodine salt coverage rate, the rate of qualified iodized salt and the non-iodized rate were detected. Results The goiter rate of children aged 8-10 years old in Longyan City was 0.94%(79/8438). The median urinary iodine was 259.12 μg/L. The consumption rate of qualified iodized salt was 97.86% (1462/1494). The iodine salt coverage rate was 99.46%(1486/1494). The rate of qualified iodized salt was 98.38 (1462/1486), and the non-iodized rate was 0.54% (8/1494). Conclusions All indicators have reached the national standard of eliminating IDD in Longyan City.     

福建省龙岩市碘缺乏病病情监测结果分析

Objective To understand the current situation of iodine deficiency diserders(IDD) in Longyan City and to evaluate the effect of prevention and control measures of IDD in order to provide evidence for formulating prevention and control tactics. Methods During the year of 2006 and 2007, the 30 primary schools were screened by population proportion survey(PPS) from the 7 counties of Longyan City. Forty children aged 8-10 years in each school were randomly selected as a group to examine thyroid, and 7 children in each group were selected to measure the urine iodine and the salt iodine at the same time. The goiter rote, the median urinary iodine, the consumption rate of qualified iodized salt, the iodine salt coverage rate, the rate of qualified iodized salt and the non-iodized rate were detected. Results The goiter rate of children aged 8-10 years old in Longyan City was 0.94%(79/8438). The median urinary iodine was 259.12 μg/L. The consumption rate of qualified iodized salt was 97.86% (1462/1494). The iodine salt coverage rate was 99.46%(1486/1494). The rate of qualified iodized salt was 98.38 (1462/1486), and the non-iodized rate was 0.54% (8/1494). Conclusions All indicators have reached the national standard of eliminating IDD in Longyan City.     

尿毒清颗粒剂对慢性肾功能衰竭脂质代谢及肾功能的影响

目的探讨中药尿毒清颗粒剂与西医结合治疗慢性肾功能衰竭(CRF)对改善脂质代谢及肾功能的作用。方法将236例CRF患者随机分为两组。对照组118例仅予西医治疗,观察组118例在西医治疗的基础上服用尿毒清颗粒剂25～40g/d,疗程2个月。比较两组治疗前后血脂及肾功能各项指标的变化。结果观察组血清TC,TG,LDL-C及apoB水平显著下降(P<0.05),HDL-C、apoA水平明显升高(P<0.05)。CRF-2及CRF-3组治疗后血清BUN、Scr水平明显下降(P<0.05或P<0.01)。结论尿毒清颗粒剂可改善CRF患者的脂质代谢紊乱,对早、中期CRF患者有改善肾功能的作用。     

2005-2007年福建省龙岩市改水降氟工程调查结果分析

1982-1988年经调查确认福建省龙岩市有10个地方性氟中毒(简称地氟病)病区,分布在永定县、武平县、长汀县、连城县、漳平市、新罗区,共6个县(市、区)、8个乡(镇)、10个自然村,其中永定县有5个地氟病病区.1984-1990年在病区进行了降氟改水,采取集中式引山泉水供水.     

大黄与伪品大黄的鉴别

大黄为蓼科植物掌叶大黄、唐古特大黄或药用大黄的干燥根及根茎.前两者习称"北大黄",后者习称"南大黄".大黄呈类圆柱形、圆锥形或块片状,表面黄棕色至红棕色,又见类白色网状纹理,或有部分棕褐色栓皮残留.质坚实,断面淡红色或黄棕色,颗粒性.横切面根茎髓部较大,其中有星点,气清香,味苦微涩,嚼之粘牙,有沙粒感,并使唾液染成黄色.大黄的乙醇浸出液于滤纸上,置紫外光灯下观察,呈棕色至棕红色荧光.粉末微量升华,可见黄色菱状针晶或羽状结晶.     

福建省龙岩市2007年8～1O岁儿童碘缺乏病监测结果

目的及时掌握龙岩市碘缺乏病流行现状和人群碘营养状况，评价干预措施落实情况及效果。方法根据福建省碘缺乏病病情监测方案的要求，2007年龙岩市疾病预防控制中心确定该市新罗、永定、连城、上杭4县（区）为病情监测县，上述各县（区）以县（区）为单位，按人口容量比例概率抽样法（PPS）开展8～10岁儿童甲状腺状况（触诊法）、尿碘水平和碘盐合格率的监测。结果8～10岁儿童甲状腺肿大率为1．26％，尿碘中位数为232．88μg/L，碘盐合格率为100％。结论龙岩市在实现消除碘缺乏病阶段目标后，病情稳定，防治效果巩固；今后应进一步加强居民食用碘盐的宣传力度，积极探索如何保持人群适宜的碘营养水平。     

纤支镜常规治疗银环蛇咬伤中毒机械通气患者的临床价值

目的探讨纤支镜常规治疗因银环蛇咬伤中毒需进行机械通气患者的临床价值.方法对20例因银环蛇咬伤中毒需进行机械通气的患者,常规采用纤支镜引导经鼻气管插管,吸痰、冲洗、入药等治疗,并随机选择了1 5例非常规治疗的银环蛇咬伤中毒的机械通气患者作为对照组.结果常规治疗组平均气管插管停留时间(104.4 ± 44.05)h,与对照组(111.8±53.33)h比较无显著性差异(P＞0.05).常规治疗组在治疗期间有较好耐受性,较少出现意外拔管(0/20),与对照组经口插管比较(5/10)有显著性差异(P＜0.05).常规治疗组无发生呼吸机相关性肺炎(VAP).常规治疗组住院时间(5.6±2 3)d,与对照组比较(8.73±5.08)d,有显著性差异(P＜0.05).讨论纤支镜常规治疗银环蛇咬伤中毒需进行机械通气的患者,可减少意外拔管,减少VAP发生,缩短住院时间,有较好的临床价值.     

2009年龙岩市8～10岁儿童尿碘水平调查

[目的]了解龙岩市人群碘营养状况。[方法]2009年,在龙岩全市抽取700名8～10岁儿童进行尿碘检测。[结果]检测700名8～10岁儿童的尿样,尿碘中位数为278.60μg/L,>300μg/L的占45.86%。尿碘中位数,男童为283.54μg/L,女童为274.18μg/L;8～10岁分别为277.12、277.79、279.73μg/L;新罗区为327.80μg/L,漳平市为333.13μg/L,永定县为291.51μg/L,上杭县为269.52μg/L,连城县为276.57μg/L,长汀县为256.11μg/L,武平县为276.57μg/L。[结论]龙岩市8～10岁儿童碘摄入量充足,碘营养状况基本良好,部分人碘营养水平高于适宜量。     

2008~2010年龙岩市医疗机构住院恶性肿瘤病例资料分析

[目的]了解恶性肿瘤病例的构成情况,为制定预防控制策略提供科学依据。[方法]对2008～2010年龙岩市二级以上医疗机构上报的住院恶性肿瘤新发病例资料进行分析。[结果]2008～2010年累计报告新发恶性肿瘤住院病例6318例。其中,2008年2191例,2009年2210例,2010年1917例;男性占61．98％,女性占38．02％;0～14岁占0．57％,15~44岁占19．07％,45~64岁占44．18％,≥65岁占36．18％;新罗区1477例,漳平市594例,永定县1105例,上杭县703例,连城县659例,长汀县766例,武平县1014例。病例数居前5位的病种依次是肺癌、结直肠肛门癌、胃癌、肝癌、乳腺癌,合计3790例,占总数的59．99％;肺癌、胃癌、结直肠肛门癌、肝癌、食管癌居男性报告病例数的前5位,乳腺癌、结直肠肛门癌、子宫颈癌、胃癌、肺癌居女性的前5位。[结论]肺癌、消化系统恶性肿瘤、女性的乳腺癌是龙岩市居民的主要恶性肿瘤。     

小剂量钙三醇对慢性肾衰竭继发性甲旁亢早期的疗效研究

目的:研究小剂量口服罗盖全治疗慢性肾衰竭(CRF)继发性甲旁亢(SHPT)早期患者的疗效和副作用.方法:将观察期间(3～12个月)血清全段甲状旁腺激素(iPTH)浓度动态升高且高达正常值3～5倍的180名CRF患者随机分为A、B两组,A组予罗盖全0.125 μg/d, B组予罗盖全0.25 μg/d口服,以血清 iPTH浓度降至正常值2.5倍即160 ng/L为观察终点;另将血清iPTH浓度高达正常值5倍以上的153例患者随机分为C、D两组,C组予罗盖全0.5 μg/d上午口服,D组以相同剂量于晚上10 h口服,以血清iPTH浓度降至正常值3倍即195 ng/L为观察终点.以到达终点的例数和时间为指标判断疗效,分别比较A、B两组及C、D两组疗效和高钙血症等副作用.结果:各组均取得良好疗效.B组有效率90.91%,明显高于A组的57.30%(P<0.01),B组到达终点时间(8.66±3.2)个月,明显早于A组(15.24±3.7)个月(P<0.01).C、D两组疗效相近,有效率分别为86.89%和84.29%(P>0.05),到达终点的时间分别为(9.51±3.1)个月和(9.97±2.9)个月(P>0.05).各组均无发生血清iPTH浓度过低(<130 ng/L).A、B两组极少发生高钙血症,发生率分别为1.11%和2.22%;D组高钙血症发生率为9.72%,明显低于C组的32.88%(P<0.01).各组肝肾功能稳定.结论:根据血清iPTH水平给予小剂量(0.125～0.5 μg/d)罗盖全治疗早期SHPT安全、有效而且经济,0.5 μg/d罗盖全于夜间使用可以减少高钙血症发生率.