脂蛋白（α）测定对脑动脉粥样硬化的临床意义

本文报告１５４例脑动脉粥样硬化患者，经ＵＶＢ治疗前后检测血浆中ＬＰ（α）浓度变化，结果均显不同程度的浓度降低，认为与病变程度呈正相关，可作为预测治疗好转的指标。并对ＡＳ患者年龄、性别和病种进行了对比观察和讨论。     

口腔粘膜病活检成败原因的病例对照分析

作者以病理档案资料分析了口腔粘膜病常见的活检原因，并以口腔恶性肿瘤切取活检样本为对照进行对比研究，分析了口腔粘膜病组织活检失败的原因。结果发现：（１）３４１例口腔粘膜活检病例中，因临床诊断为口腔扁平苔藓而活检者最多，占３３．４３％。（２）口腔粘膜病活检临床与病理诊断的一致性并不理想，最高者（口腔扁平苔藓）为７５．４４％。（３）口腔粘膜病活检的总失败率高于对照（口腔恶性肿瘤）的总失败率，差异有显著性，其中最常见的失败原因是活检过浅，发生率为１８．７７％，与对照（４．４％）相比，差异有显著性。作者认为，取材过浅是口腔粘膜病活检特有失败现象。     

乙型肝炎病毒感染状态与肝细胞癌的关系

乙型肝炎病毒(HBV)持续感染与肝细胞癌(肝癌)发生的关系早以被证实,但不同的HBV感染状态下,肝癌发生的危险性不一。我们通过观察病例组和对照组不同的HBV感染状态下肝癌发生的危险性,旨在为确定肝癌二级预防中高危人群提供证据。材料与方法　　一、研究对象　　病例:系1994年全年上海医科大学中山医院肝癌研究所所有的经病理证实为肝细胞癌140例,男∶女为4.8∶1平均年龄48岁;　　对照组:(1)同期在中山医院手术的外科病例125例,查过血清HBV抗原、抗体,男∶女为1.6∶1,平均年龄46岁;(2)某工厂全体35～60岁的职工,共530例,男∶女为8.6∶1,…     

WILSON'S DISEASE (HEPATOLENTICULAR DEGENERATION CLINICAL ANALYSIS OF 80 CASES

80 typical cases of Wilson's disease were observed over 54 years, 58 0f whom were hos- pitalized, an incidence of 19.7 per 100,0'00 general hospital inpatients and 522 per 100,0001 neurologic inpatients. The average age of onset was 23.5 years. Average age of onset before 15 years was 50To, between 20-30 26.91To and before 30 76.5.9To. 51.25'Io of our 80 patients had first involvement of the nervous system commencing at an average age of 25.2 years and 95To exhihited neurologic symptoms and signs. 39.99To had primary onset of hepatic disorder at an average age of 14.2 years and 80% showed evidence of hepatic dysfunction. 3.99To had renal involvement as first manifestation of disease and 40V/o showed evidence of renal damage. Aminoaciduria was demonstrated in 6.25%, 0.5'/o had affection of bones and joints, 2.5'/o had mental sympt.oms as first manifestation of the disease and 46.25% showed mental symptoms. 3 showed evidence of heart involvement. EEG findings and study of copper content of brain and liver wiU be pre- sented in other papers. Autopsy was performed on 5 with typical findings of Wilson's disease. Copper oxidase activity was lowered in 95%. Kayser-Fleischer ring was found in 73.75%. Urinary copper content was high in 96.97To (32/33 cases). Serum copper content was low in 65.22T。 (15;23 cases). 62 0f our 80 patients (77.50To) had well documented family histories. It was posi- tive in 10 patients of 9 families and highly suspected in another 4 in agreement with auto- somal recessive heredity. With regard to pro- gnosis 11 patients remain apparently healthy, 38 continue working or studying while taking treat- ment, 24 are invalids and 7 died. It appears that the longer the interval between onset, of disease and diagnosis, the worse the prognosis, indicat- ing the importance of early diagnosis and treat- ment.     

世界卫生组织(World Health Organisation简称WHO)简介一起源与发展

国际卫生合作始于1857年7月23日在巴黎召开的第一次国际卫生会议。会议目的仅限于协调欧洲各国,尤其是地中海沿岸各国之问有矛盾的,互相抵触耗费巨大的海关检疫条例,使之降低到起码的安全程度。此检疫条例一直系针对防止自东地中海沿岸国输入鼠疫的。其后在地中海沿岸港口用以防范短时出现的黄热病,而后又防止霍乱对欧洲的第一次袭击。直     

氧自由基在复发性口疮发病中的作用

为探寻多因素导致复发性口的可能共同途径，对２２例发作期，１５例间歇期ＲＡＳ患者，３２例健康正常人血浆中８项生化指标进行研究，其结果显示：（１）ＲＡＳ患者超氧化物歧休酶活性有下降趋势；ＭｎＳＯＤ有上扬倾向，而ＣｕＺｎＳＯＤ则出现明显下降；（２）过氧化物脂质水平明显高于对照组；（３）总氨基己糖和氨基葡萄糖含理高于对照组，而氨基半乳糖差异不大；（４）上述指标发作期与间歇斯差异无显著性。（５）多元方差分析     

晚期马蹄内翻足的矫正

1985年～1987年,我院共收治晚期马蹄内翻足6例。男4例,女2例。年龄13～21岁。双侧2例,右侧3例,左侧1例共8只足。先天性4例,脊髓灰质炎后遗2例。