角膜植入性囊肿二例

角膜植入性囊肿二例贺，孙秉基，李建新角膜植入性囊肿临床上极为少见，自１８５３年Ａｐｐｉａ首先报告第１例以来，迄今文献累积３０余例。国内尚未见报告。我们遇到２例，现报告如下。例１女，３０岁，右眼角膜中央有一白色混浊，逐渐增大，伴视力下降３年。近半年病变...     

脂蛋白（α）测定对脑动脉粥样硬化的临床意义

本文报告１５４例脑动脉粥样硬化患者，经ＵＶＢ治疗前后检测血浆中ＬＰ（α）浓度变化，结果均显不同程度的浓度降低，认为与病变程度呈正相关，可作为预测治疗好转的指标。并对ＡＳ患者年龄、性别和病种进行了对比观察和讨论。     

鲨鱼油口服乳中喃氟啶的含量测定

鲨鱼油口服乳是由多种药物及辅料所组成。其含量测定较为繁琐，经过我们摸索利用紫外可见分光光度计测定喃氟啶的含量，省去了繁琐的步骤，取得了比较满意的结果。     

口腔粘膜病活检成败原因的病例对照分析

作者以病理档案资料分析了口腔粘膜病常见的活检原因，并以口腔恶性肿瘤切取活检样本为对照进行对比研究，分析了口腔粘膜病组织活检失败的原因。结果发现：（１）３４１例口腔粘膜活检病例中，因临床诊断为口腔扁平苔藓而活检者最多，占３３．４３％。（２）口腔粘膜病活检临床与病理诊断的一致性并不理想，最高者（口腔扁平苔藓）为７５．４４％。（３）口腔粘膜病活检的总失败率高于对照（口腔恶性肿瘤）的总失败率，差异有显著性，其中最常见的失败原因是活检过浅，发生率为１８．７７％，与对照（４．４％）相比，差异有显著性。作者认为，取材过浅是口腔粘膜病活检特有失败现象。     

乙型肝炎病毒感染状态与肝细胞癌的关系

乙型肝炎病毒(HBV)持续感染与肝细胞癌(肝癌)发生的关系早以被证实,但不同的HBV感染状态下,肝癌发生的危险性不一。我们通过观察病例组和对照组不同的HBV感染状态下肝癌发生的危险性,旨在为确定肝癌二级预防中高危人群提供证据。材料与方法　　一、研究对象　　病例:系1994年全年上海医科大学中山医院肝癌研究所所有的经病理证实为肝细胞癌140例,男∶女为4.8∶1平均年龄48岁;　　对照组:(1)同期在中山医院手术的外科病例125例,查过血清HBV抗原、抗体,男∶女为1.6∶1,平均年龄46岁;(2)某工厂全体35～60岁的职工,共530例,男∶女为8.6∶1,…     

肺栓塞135例临床分析(附尸解30例)

肺动脉栓塞虽然不是一个独立的疾病,但在临床上却相当常见。在美国估计死于本病者,每年接近20万人。Moser在病理解剖中发现城市居民死亡者几乎2/3有肺栓塞。但由于本病缺乏特异的实验室诊断方法,生前常不易得到确诊。例如经解剖证实有肺栓塞者,80—90％生前未得到诊断。我国目前有关这     

WILSON'S DISEASE (HEPATOLENTICULAR DEGENERATION CLINICAL ANALYSIS OF 80 CASES

80 typical cases of Wilson's disease were observed over 54 years, 58 0f whom were hos- pitalized, an incidence of 19.7 per 100,0'00 general hospital inpatients and 522 per 100,0001 neurologic inpatients. The average age of onset was 23.5 years. Average age of onset before 15 years was 50To, between 20-30 26.91To and before 30 76.5.9To. 51.25'Io of our 80 patients had first involvement of the nervous system commencing at an average age of 25.2 years and 95To exhihited neurologic symptoms and signs. 39.99To had primary onset of hepatic disorder at an average age of 14.2 years and 80% showed evidence of hepatic dysfunction. 3.99To had renal involvement as first manifestation of disease and 40V/o showed evidence of renal damage. Aminoaciduria was demonstrated in 6.25%, 0.5'/o had affection of bones and joints, 2.5'/o had mental sympt.oms as first manifestation of the disease and 46.25% showed mental symptoms. 3 showed evidence of heart involvement. EEG findings and study of copper content of brain and liver wiU be pre- sented in other papers. Autopsy was performed on 5 with typical findings of Wilson's disease. Copper oxidase activity was lowered in 95%. Kayser-Fleischer ring was found in 73.75%. Urinary copper content was high in 96.97To (32/33 cases). Serum copper content was low in 65.22T。 (15;23 cases). 62 0f our 80 patients (77.50To) had well documented family histories. It was posi- tive in 10 patients of 9 families and highly suspected in another 4 in agreement with auto- somal recessive heredity. With regard to pro- gnosis 11 patients remain apparently healthy, 38 continue working or studying while taking treat- ment, 24 are invalids and 7 died. It appears that the longer the interval between onset, of disease and diagnosis, the worse the prognosis, indicat- ing the importance of early diagnosis and treat- ment.