伊曲康唑治疗生殖器念珠菌病36例

目的探讨伊曲康唑治疗生殖器念珠菌病的方法.方法口服伊曲康唑200 mg,1次/d,外用达克宁霜或洁尔阴,连用7天.结果治愈88.89 %(32/36),好转8.33 %(3/36),无效2.78 %(1/36),总有效率97.22 %(35/36).结论口服伊曲康唑外用达克宁霜或洁尔阴7日疗法,治疗生殖器念珠菌病疗程短,治愈率高.     

联苯苄唑霜治疗浅部真菌病疗效观察

我科于1991年4月～12月应用1％联苯苄唑霜对60例皮肤浅部真菌病患者进行了治疗,现将结果报告如下。 1 临床资料 1.1 本组男36例,女24例。年龄5～62岁,平均31岁。病程3天～20年,平均11.64天。股癣27例,体癣25例,花斑癣2例,手足癣6例。 1.2 治疗方法:所用的1％联苯苄唑霜为军事     

石家庄地区疥疮的发病情况(附66例报告)

疥疮是由疥虫引起的一种接触性传染性皮肤病。解放后在我国虽已少见,但从1976年以来国内个别地方出现了流行,石家庄地区亦不断发生此病,并且逐渐增多,因而应引起重视。现将我科近半年来发现的66例疥疮报告如下:     

猫癣引起人患体癣12例报告

体癣由浅部真菌(霉菌)感染,是常见的一种皮肤病。由猫身上的羊毛样小芽孢菌(即羊毛状小孢子菌)引起人患体癣的情况,国内北京皮肤性病研究所出版“皮肤真菌病图谱”上已作描述。现将我院发现12例报告如下:     

科玛嘉显色培养基检测深部念珠菌感染538例分析

目的 对科玛嘉念珠菌显色培养基在深部念珠菌标本检测中应用的评价。方法 对直接镜检阳性的538例患者的便、痰、尿标本，采用科玛嘉显色培养25℃ 48—72h，根据培养基表面菌落不同的颜色，鉴定念珠菌的种类。结果 538例深部标本，白念珠菌266株，热带念珠菌105株，光滑念珠菌77株，克柔氏念珠菌59株。结论 科玛嘉念珠菌显色培养基优于常规沙氏生化法，且快速、简便、准确地分离鉴定各种念珠菌，可做为检测深部念珠菌的首选方法。     

盐酸戊乙奎醚减少老年女性患者术后躁动的作用

目的 本研究将盐酸戊乙奎醚作为老年女性患者麻醉前用药,与传统的氢溴酸东莨菪碱进行比较,评价其对术后躁动的影响。方法选择年龄65以上的老年女性患者。气管内插管全身麻醉下择期行甲状腺手术治疗的老年患者,随机分两组。麻醉前30min,Ⅰ组患者予盐酸戊乙奎醚1mg肌肉注射。Ⅱ组患者氢溴酸东莨菪碱0．3mg肌肉注射。记录用药前、用药后10min、20min、30min的收缩压、舒张压、心率、脉搏氧饱和度、麻醉时间,手术时间和苏醒时间和术后躁动发生情况。结果Ⅰ组患者术后躁动的发生率比Ⅰ组低,差异有统计学意义（P〈0．05）。结论 与氢溴酸东莨菪碱相比,盐酸戊乙奎醚显著减少老年女性患者术后躁动的发生率,是一种较理想的麻醉前用药。     

国产庐山霉素泡腾片治愈热带念珠菌引起皮肤慢性顽固性溃疡一例报告

热带念珠菌(candida tropicalis)又称热带假丝酵母菌,是念珠菌属中的一种,为条件致病菌,但由热带念珠菌引起皮肤慢性顽固性溃疡实属罕见,并外用国产庐山霉素新的剂型泡腾片很快治愈。查阅手头文献,还未见报导,故提出以供同道参考。患者岳××,男51岁、农民、河北省井陉县人。主因左足背溃烂十年,于1981年8月就诊。     

中西医结合治疗体,股癣临床研究

本文对１７４例体、股癣患者随机分为治疗组和对照组。治疗组用治癣汤熏洗并外涂皮康霜：对照组单纯外涂皮康霜。经过临床对比观察，治疗组的治愈率为８１．８２％对照组为５０％，Ｐ〈０．０５有显著差异：治愈时间治疗组比对照组缩短５．１８天。提示中西医结合治疗体、股癣效果满意。     

孢子丝菌病5例报告

孢子丝菌病是由申克型孢子丝菌引起的一种慢性传染性深部真菌病。1951年在上海发现迄今已报导百余例。我科两年来遇到5例,均经培养证实,报导如下。     

Mechanisms,clinically curative effects,and antifungal activities of cinnamon oil and pogostemon oil complex against three species of Candida

The anti-fungus mechanisms and curative effects of cinnamon oil and pogostemon oil complexes to wards intestinal Candida infections were investigat ed.We measured the minimal inhibitory concentra tion(MIC) values of the complexes against Candida using proportionally-diluted test-tube medium and examined the evolution of the morphology and structures of Candida albicans using scanning electronic microscopy(SEM) and transmission elec tronic microscopy(TEM).We found that the aver age MIC values of the complexes against the fung were 0.064 mg/mL(cinnamon oil),0.032 mg/mL(pogostemon oil) for Candida albicans,0.129 mg/mL(cinnamon oil),0.064 mg/mL(pogostemon oil for Candida tropicalis,and 0.129 mg/mL(cinnamon oil),0.064 mg/mL(pogostemon oil),for Candida krusei.SEM examination over a 24-48 h period showed that the morphology of Candida albicans cells changed significantly.Irregular hollows ap peared on the surfaces,inside organelles were destroyed and the cells burst after treatment.TEM examination over a 48-72 h period indicated that the cell walls were damaged,organelles were destroyed and most cytoplasms became empty bubbles.Sixty intestinal Candida-infected patients were treated with a capsule containing cinnamon and pogostemon oil.The curative ratio was 71.67%(43/60),and the improvement ratio was 28.33%(17/60),giving a to talratio of 100%.Thus,the cinnamonoil and pogostemon oil complexes had strong anti-funguseffectsag ainst Candida albicans,Candidatropicalis,and Candidakrusei.They impacted the morphology and sub-micro structures of the fungus within48-72h,and eventually denatured and killed the cells.The complexes have also shown considerable curative effects to intestinal Candida infections.