福建人体脑囊虫病4例报告

<正> 我们自1985年以来收治了来自仙游县4例患者,现报告如下: 例一,王××,女,20岁,仙游县度尾乡人,务农。以头痛8个月伴视力下降,肥胖和嗑睡近6个月为主诉于1985年5月19日入院。既往否认有食生或未煮熟的“米猪肉”史,月经未来潮。查体:神清,肥胖外观,     

《金匮要略》“相和性”思维初探

[目的]探究《金匮要略》"相和性"天人一体思维,并以"整体观念"作为应用法则来作出分析,以期更全面地理解《金匮要略》相关条文,从而拓宽思路,提高临床疗效。[方法]从《金匮要略》第一、第六和第十六篇中撷选"整体观念"有关条文,并以天体相和、天人相和、人体相和等三个代表范畴,追本溯源为"相和性"思维法则作出具体说明。[结果]"相和性"的思维特点是"整体观念"。"相和性"在《金匮要略》的具体体现,就是指在"整体观念"的大原则下,自然、人体,自然与人体之间所达到一种"相和呼应"的和谐状态。[结论]通过"相和性"来说明"整体观念"存在的合理性,是《金匮要略》之中有关于中医学思维的一大特色,同时这也是中医学基础理论的特点所在。掌握《金匮要略》"整体观念"之"相和性"思维法则,不仅有助于对中医学理法方药的体会发挥,而且也能提高医者临床水平。     

甲状腺癌术后复发的相关因素分析

目的 探讨甲状腺癌术后复发的相关危险因素.方法 对经手术治疗的甲状腺癌患者368 例,分析其术后复发与临床、病理因素关系,并采用多因素Logistic 回归方法分析其危险因素.结果 甲状腺癌术后复发与患者性别、年龄无明显相关性(P>0.05 ),而与肿瘤大小、病理类型、手术方式及是否作淋巴结清扫相关(P<0.05 ),肿瘤体积大、恶性程度高、手术切除范围大、未作淋巴结清扫者的术后复发率显著高于肿瘤小、恶性程度低、手术切除范围小、作淋巴结清扫者的复发率(P<0.05 ).Logistic 回归分析表明女性和年龄≥43 岁不是甲状腺癌术后复发的危险因素,而肿瘤最大直径≥4cm 、组织学恶性程度高、手术切除范围大及不作淋巴结清扫均为甲状腺癌术后复发的危险因素.结论 肿瘤体积大、病理组织学恶性程度高、手术切除范围广及不作淋巴结清扫是甲状腺癌术后复发的危险因素.     

人工股骨头置换治疗股骨颈新鲜骨折随访5年疗效评价

目的 探讨人工股骨头置换术治疗股骨颈新鲜骨折的治疗效果.方法 分析了1995年12月～1998年1月采用人工股骨头置换治疗股骨颈新鲜骨折79例,男32例,女47例.骨折分型GardenⅡ型13例,GardenⅢ型38例,GardenⅣ型28例.单极股骨头46例,双极股骨头33例.结果 术后随诊3年～7年6月（平均4年8月）.按Harris标准评定疗效：单极股骨头置换优良率69.6%,双极股骨头置换优良率81.8%.X线片观察：单极股骨头置换组：髋臼磨损硬化14例（30.4%）,假体松动7例（39.1%）.双极股骨头置换组:髋臼磨损硬化4例(12.1%),假体松动7例（21.2%）.结论 (1)对于老年人有移位的股骨颈骨折,股骨头置换为优先考虑的有效方法.(2)双极股骨头置换术疗效优于单极股骨头置换术.3.改进骨水泥制作和应用现代骨水泥充填技术固定假体可大大提高人工股骨头置换的长期疗效.     

MMP—2和MMP—9在人脑原发性胶质瘤侵袭中的作用

目的 探讨基质金属蛋白酶MMP－2和MMP－9在原发性人脑胶质瘤侵袭行为中的作用。方法 用免疫组织化学S－P法检测MMP－2和MMP－9在胶质瘤和脑内转移瘤中的表达情况;同时通过测量CT影像上的瘤周水肿范围,并与免疫组织化学表达结果作对照比较。结果 1.45例人脑胶质瘤档本中,MMP－2和MMP－9的瘤细胞阳性率分别为35.5%、62.2%,两者之间差别显著（P＜0.05）;MMP－2、MMP－9在高度恶性胶质瘤标本中阳性率分别为56.5%、91.3%,两者之间亦存在明显差别（P＜0.01）;2.MMP－2的染色强度与胶质瘤侵袭指标－－CT瘤周水肿范围无关（P＞0.05）,而MMP－9的染色强度则与其有关（P＜0.05）;也与高度恶性胶质瘤中的表达率无统计学差别（P＞0.05）。结论 MMP－2、MMP－9在人脑胶质瘤中可以作为恶性表型及侵袭指标之一,亦可体现胶质瘤基质降解表型,但不能作为转移表型。其中,MMP－9在人脑胶质瘤侵袭中可能发挥着更重要的作用。     

氟伐他汀对缺血性脑卒中患者的疗效观察及护理措施

Objective To explore the effect and nursing main points of fluvastatin on the patients with cerebral arterial thrombosis. Methods Eighty-five patients with cerebral arterial thrombosis were randomly divided into three groups. Group Ⅰ was the negative control group. Group Ⅱ was the conventional-dose therapy group and group Ⅲ was the high-dose therapy group. Each group was treated with related therapy and care. The blood lipids in all groups were tested before the treatment, 4 weeks, 12 weeks and 24 weeks after the treatment; the carotid intima-media thickness (IMT) were measured by the Germany SEQUOIAS-512-B ultra machine before the treatment and 24 weeks after the treatment; At the same time, the side effects of fluvastatin were recorded. Results The results of blood lipid tests showed that the LDL, TC and TG in two treated groups were significantly decreased compared to negative control group (P<0.05). After treated for 24 weeks, the carotid intima-media thickness (IMT) in two treated groups were significantly reduced (P<0.05); the side effects of fluvastatin were infrequent and there was no significant different among the three groups (P>0.05). Conclusion The effects of different doses of fluvastatin on cerebral arterial thrombosis were significantly different. With the dose of fluvastatin increased, the serum LDL-L and TC reduced more obvious and the inhibition on carotid atherosclerosis shows more obvious, and the side effects did not increased.     

脊髓栓系综合征的研究进展

脊髓栓系综合征(tethered cord syndrome,TCS)系先天或后天性因素致异常组织牵拉脊髓,使其活动受限,造成脊髓圆锥张力异常增加,由此引发的一系列临床症状和体征,主要包括排尿、排便功能障碍,双下肢运动、感觉障碍,躯体畸形,疼痛等。因涉及多系统器官的病变,可导致严重的后遗症和高的致残率,同时部分病例起病较隐蔽,有时较易误诊,需临床医师加深认识,提高早期诊断率,以使患者得到尽早治疗,获得最大收益。近几年随着影像学、神经电生理学、显微外科技术的发展,对该疾病的认识取得了较大的进展,现对其病因、发病机制、诊断和治疗作一综述。     

半氧化苏木素应用于组织切片的优越性

半氧化苏木素应用于组织切片的优越性福建医科大学附属第二医院病理科柳悦莲王莉莉林志雄为了节省苏木素用量，染液配制后即可使用，且染色力强。我们近年选择了吉尔（Ｇｉｌ）氏半氧化苏木素为配方作ＨＥ染色，报道于下。一、染液配制苏木精２ｇ，乙二醇或无水酒精２５０...     

氟伐他汀对缺血性脑卒中患者的疗效观察及护理措施

Objective To explore the effect and nursing main points of fluvastatin on the patients with cerebral arterial thrombosis. Methods Eighty-five patients with cerebral arterial thrombosis were randomly divided into three groups. Group Ⅰ was the negative control group. Group Ⅱ was the conventional-dose therapy group and group Ⅲ was the high-dose therapy group. Each group was treated with related therapy and care. The blood lipids in all groups were tested before the treatment, 4 weeks, 12 weeks and 24 weeks after the treatment; the carotid intima-media thickness (IMT) were measured by the Germany SEQUOIAS-512-B ultra machine before the treatment and 24 weeks after the treatment; At the same time, the side effects of fluvastatin were recorded. Results The results of blood lipid tests showed that the LDL, TC and TG in two treated groups were significantly decreased compared to negative control group (P<0.05). After treated for 24 weeks, the carotid intima-media thickness (IMT) in two treated groups were significantly reduced (P<0.05); the side effects of fluvastatin were infrequent and there was no significant different among the three groups (P>0.05). Conclusion The effects of different doses of fluvastatin on cerebral arterial thrombosis were significantly different. With the dose of fluvastatin increased, the serum LDL-L and TC reduced more obvious and the inhibition on carotid atherosclerosis shows more obvious, and the side effects did not increased.