两层分离切除法在眼袋整形术中的应用及探讨

目的：为了提高眼袋手术的远期效果,更好的去除皮肤细小皱纹,以及眼轮匝肌松弛下垂。方法：以传统的三种眼袋整形手术方法为基础,对198例眼袋整形的患者进行了皮肤和肌肉两层分离法的术式研究。两层分离法主要采用皮肤与眼轮匝肌不等量、不同步切除。结果：改进后的两层分离法手术更好地处理了下睑肌肉松垂问题;术后随访,1个月至3年,临床效果满意,术后并发症较少。结论：两层分离切除法比较传统的眼袋手术方法,治疗效果更好。     

尿微量蛋白在2型糖尿病肾病诊治中的作用研究

目的：探讨分析尿微量蛋白在2型糖尿病肾病诊治中的作用。方法：选择2型糖尿病患者68例作为观察组,选择同期65名健康者为对照组。采用散射比浊法测定两组尿蛋白、转铁蛋白（TRF）、β2-微球蛋白（β2-MG）、微量清蛋白（mALB）、尿a1-微球蛋白（al-MG）水平。结果：观察组尿蛋白、尿微量蛋白阳性率分别为23.52%和57.35%,与对照组比较差异有统计学意义（P〈0.05）;mALB、β2-MG、a1-MG及TRF水平,尿蛋白阳性组高于阴性组,尿蛋白阴性组高于健康组,差异均有统计学意义（P〈0.05）;TRF、alMG、mAlb及β2-MG水平,5年以上病程患者显著高于5年以下病程患者,5年以下病程患者高于健康组,差异均有统计学意义（P均〈0.05）。结论：4种尿微量蛋白联合检测,可以为早期2型糖尿病肾病的诊断、监测提供可靠依据。     

血吸虫病免疫诊断试剂的质量评价

目的评价目前我国应用的部分血吸虫病免疫诊断试剂的质量。方法采用血吸虫病诊断试剂IgG抗体免疫血清国家参考品对目前我国应用最广泛的8个血吸虫病免疫诊断试剂进行质量评价。结果8个血吸虫病免疫诊断试剂盒均无国家食品药品监督管理局生产批准文号,其中6个质量较好,精密性一致;另外2个物理检查及外观不合格。结论目前市场上使用的血吸虫病免疫诊断试剂盒质量良莠不齐,应加强规范和管理。     

阜康市农村饮用水及水源地卫生防护现状调查

目的 了解阜康市农村饮用水水质及水源卫生防护现状.方法 按照《生活饮用水卫生标准检验方法》(GB5750-85),对全市22处水源水质进行分析检测,并对水源卫生防护状况进行了调查. 结果 检测22份水质的308个项目,综合合格289项次,合格率为93.83%,其中微生物超标2份占9.09%,理化超标7份占31.82%,水源地未设置防护带和防护栏的达86.36%. 结论 农村水源地的卫生防护和管理尚不如人意,应加大对农村水源地的卫生防护及管理.     

脑心通对实验性动脉硬化兔血管MMP-3基因的影响

目前认为,基质金属蛋白酶（MMP）与动脉粥样硬化（AS）斑块的不稳定性及急性冠脉综合征的发生密切相关.有关中药对MMP研究的报道较少.近年来的研究发现,脑心通药物能够缓解冠心病心绞痛的症状,并有保护内皮细胞及抗AS作用.为了探讨脑心通对MMP-3的影响,我们应用高脂饮食建立了兔动脉粥样硬化模型,观察MMP-3基因的表达,报道如下.     

50例产单核细胞李斯特菌血流感染分析

Objective To analyze the characteristics of bloodstream infection of Listeria monocytogenes and provide basis for the diagnosis and treatment of the disease. Methods We retrospectively analyzed the cases of Listeria monomyrhosi bloodstream infection in Peking Union Medical College Hospital (PUMCH) from April 2012 to April 2022. The age, sex, onset time, underlying disease, symptoms, diagnosis, treatment and prognosis of the patients were analyzed, as well as the changes of white blood cells (WBC), neutrophils, lymphocytes, and C-reactive protein (CRP) before and after anti-infection treatment. Results Fifty cases of Listeria monocytogenes bloodstream infection confirmed by blood culture were involved. The age of patients ranged from 0 to 82 (43.7±20.0) years old, among whom 20.0% were over 60 years old. The onset time of patients was the highest in spring (44.0%), followed by winter (24.0%), and relatively fewer in summer and autumn (14.0%-18.0%). The median diagnosis time was 3 days (1-60 days). After the etiological diagnosis, 45 patients (90.0%) had underlying diseases or pregnancy status, and 45 patients were adjusted to the target antibacterial treatment mainly with carbapenems (48.9%) and penicillins (44.4%). The level of WBC, neutrophils, lymphocytes, monocytes, and CRP after treatment were significantly lower than those pre-treatments (P<0.05). Among all patients, 36 cases (72.0%) were treated according to the Antimicrobial Treatment Guidelines for Fever Sanford, of which 26 cases (72.2%) were discharged from the hospital, two cases died, one case was transferred to other hospitals, and 7 cases had a poor prognosis. Conclusions Autoimmune diseases, tumor diseases, pregnant patients are susceptible to Listeria monocytogenes infection. Penicillins are the first choice for effective empiric therapy. For the patients allergic to penicillins, trimethoprim/sulfamethoxazole or meropenem could be used. © 2023 China Tropical Medicine. All rights reserved.