鼻内镜手术治疗慢性侵袭性真菌性鼻窦炎45例

目的探讨鼻内镜下治疗慢性侵袭性真菌性鼻窦炎的疗效。方法在鼻内镜下对45例慢性侵袭性真菌性鼻窦炎患者行鼻窦清创术,部分病例加行下鼻道开窗术,彻底清除鼻窦病变组织及鼻病变黏膜和骨质,充分开放鼻窦,术后应用大扶康冲洗术腔,并定期行鼻内镜检查。结果随访6个月至6年,治愈41例,复发4例。复发病例经再次鼻内镜手术后治愈,无手术并发症。结论鼻内镜下鼻窦清创术是治疗侵袭性真菌性鼻窦炎的重要手段,术后定期复查并辅以大扶康术腔冲洗,疗效良好。     

耳鸣匹配试验与耳鸣障碍问答表检测耳鸣方法的比较

目的寻找有效便捷的耳鸣测试方法.方法以耳鸣匹配试验和耳鸣障碍问答表分别进行测试.结果耳鸣匹配试验表明的是一个量化指标,耳鸣障碍问答表是患者本人的自测结果,只能大致反映耳鸣程度.结论耳鸣匹配试验是临床测试耳鸣的一个重要指标.     

80例假性球麻痹并发肺部感染的原因分析与护理对策

假性球麻痹是由于两侧皮质脑干束损害或脑干中风后致双侧延髓束受损．造成支配咽喉肌群活动的疑核及支配舌肌的舌下运动神经核出现核上性损害．是脑中风后较为常见的复杂的症状之一.     

皮肤消毒效果对照监测

静脉输液是应用于临床抢救、治疗最常用的无菌技术操作之一,患者静脉穿刺处皮肤消毒的质量和效果直接关系到医院感染与不良反应的发生。对静脉输液皮肤消毒的两种方法的效果,我们做了80例静脉输液穿刺部位对照监测和实验,报告如下。1　材料与方法1.1　材料　第1组:患者选自门诊输液室,3%碘酊、75%酒精、试管内装有10毫升灭菌生理盐水和棉拭子,灭菌棉签、普通营养琼脂平板、4%吐温80中和剂两种。第2组:患者仍选自门诊输液室,1%稀碘酊、试管内装有10毫升生理盐水和棉拭子,灭菌棉签、普通琼脂平板、0.4%吐温80中和剂两种。1.2　静脉输液皮肤消…     

神经生长因子基因转染联合强化铁营养防治豚鼠爆震性聋的实验研究

Objective To study the protective effects of adenovirus-mediated human beta-nerve growth factor gene (hNGFβ) transfer combined with iron fortified nutrition on blast hearing damage in guinea pigs. Methods Deafness was induced by blast (172dB SPL) in 35 healthy guinea pigs. Seven days after noise exposure, 10 guinea pigs were inoculated with adenovirus-mediated hNGFβ (Ad-hNGFβ) into the perilymphatic space (the gene group), another 10 guinea pigs were given hNGFβ combined with iron fortified nutritional diet (the combination group), still another 10 guinea pigs were inoculated with artificial perilymphatic fluid (APF), and 5 guinea pigs served as control, given neither medicine nor noise exposure. Auditory brainstem response (ABR) threshold shifts were monitored in the guinea pigs before blast exposure and after gene transfer. Changes in cochlear morphology were examined with immunohistochemical and HE staining. Results One week after successful inoculation of hNGFβ, it was noted that Ad-hNGFβ protein was expressed in each turn of the cochlea, and its intensity was almost equal. After gene transfer in the combination group and the gene group, ABR threshold shifts at week 1 and 4 were significantly smaller than those of the APF group. HE staining showed that the number of the spiral ganglion cells in the combination group and the Ad-hNGFβ group was significantly higher than that of the control group after 4 weeks (P<0.01). Conclusions Ad-hNGFβ combined with iron fortified nutritional diet was effective in the prevention and treatment of blast hearing damage of cochlear hair cells.     

基因芯片在耳鼻咽喉-头颈外科学中的应用

基因芯片(gene chip)是20世纪90年代发展起来的一种新型实用的高新生物技术.其突出特点是具有高度的并行性、多样性、微型性和自动化,已成为高效、快速、大规模获取相关生物信息的重要手段.     

鼻腔鼻窦血管球瘤与恶性血管球瘤

鼻腔、鼻窦血管球瘤十分少见,鼻腔、鼻窦恶性血管球瘤更为罕见,其临床表现类似鼻息肉,早期诊断甚难,通常于手术标本病理检查后才明确诊断.本文结合综述者近期对一例鼻腔、鼻窦恶性血管球瘤的诊治体会,对鼻腔、鼻窦血管球瘤的一般情况、临床表现、诊断、病理、治疗和预后作简要综述.     

制备耳蜗扫描电镜标本的体会

耳蜗标本的几何形态复杂,在组织结构方面又有质量密度差异很大的骨迷路和膜迷路,制备扫描标本时很易造成人工损伤,难以得到理想的标本。现将我们在制备耳蜗扫描标本中的初步体会介绍如下。 1.用灌注法与浸润法联合固定。由于耳蜗结构有大量的骨质,上皮直接贴附于骨质上,两种成份质量密度差异很大,故容易分离断裂,而毛细胞的听毛很细弱,极易损伤和自溶。因此固定很重要,     

17例癫痫患者的家庭康复护理体会

癫痫是由于脑细胞群异常的超同步放电引起的脑功能紊乱,发作突然、短暂、病程长、痛苦多,绝大多数患者需在家中进行较长时间的康复治疗,现将2年来对家庭护理癫痫患者的体会总结如下。 一般资料:本组男9例,女8例,年龄10～55岁。其中大     

临证忌望文断章

中医理论乃众医临证经验之总结,它反过来又指导于临证实践,在临证实践中不断得以验证并逐步提高.在临证中.对医理万勿断章取义,否则便会迷途而延误治疗.现试举临证1例而议之,以飨同道.