对加强药品配送机构监督管理的思考

国家食品药品监督管理局在《关于全面开展加强农村药品监督网络建设促进农村药品供应网络建设工作的指导意见》中明确指出：“为配合药品配送、连锁进县到乡，各省（区、市）食品药品监督部门可以进行建立区域性药品配送站的研究和指导。在进行研究和探索过程中，鼓励将基层的药品批发企业改组成区域性药品配送站”。     

慢性根尖周炎319颗患牙的治疗与分析

目的：通过对319颗慢性根尖周炎患牙，采取根管超充填的方法进行治疗，观察疗效。方法：对根尖密度影较大的患牙，采用比塔派克斯根管充填剂超充;根尖密度影较小的患牙采用氧化锌碘仿丁香油糊剂稍超充填。结果：治疗的319颗患牙，有效311颗，总有效率达90％以上。结论：对慢性根尖周炎采取超充填治疗的方法是可行的，可以缩短疗程，促进患牙愈合。     

超短波治疗输卵管不通的体会

输卵管不通其主要原因是由于各种感染因素所引起的输卵管炎症，如全身感染或人工流产，药物流产等其它原因引起的逆性型感染，炎症长期不愈，组织水肿及纤维组织大量增生，使输卵管不通，形成输卵管性不孕。如果堵塞不全，即输卵管通而不畅，易发生宫外孕。临床上经超短波治疗效果明显，将治疗体会介绍如下：     

在Suzuki反应中，催化剂循环使用和产物回收的简便方法

在钯催化的Suzuki交叉偶联反应中，以聚环氧乙烷-甲醇为混合溶剂，反应结束后用正庚烷提取，产物进入非极性相，收率〉90％。催化剂留在极性相，可循环使用多次。     

筛窦铅弹一例

患者女，2l岁，未婚，左眼被汽枪铅弹击伤而入院．检查见左上、下眼险青紫肿胀，左上睑外眦处可见黄豆大伤口，周边不整齐．拍片见左侧筛窦后方有一大小约为0．8cm×0．6cm的金属异物，中线外左侧，鼻根后约3cm；下约1cm局麻下循伤口探查瘘道，     

Changes of Unit Discharge of the Medullary Respiratory Neurons during Apnea

Changes of the neuronal discharge of 128 medullary respiratory unitswere recorded and studied during the period of expiratory apnea induced reflexlyby intracarotid sinus injection of sodium citrate in rabbits.Generally,theneuronal discharge of inspiratory units began,stopped and recovered at the sametime with those of the phrenic nerve.But,about 5% the phase-spanninginspiratory units near the obex showed a different time course with the dischargeof the phrenic nerve.They fired continuously in a low frequency while thephrenic nerve was quiet.When increasing progressively and approaching to acertain level,the firing rate increased abruptly and at the same time phrenic nervebegan to fire.So it seemed that they acted as the pacemaker of inspiration.Comparison of the cycle-triggered histograms(CTH)of these inspiratory unitswith those of phrenic nerve showed clearly the above mentioned phasicrelationship.They started firing before the phrenic nerve,but they reached theirmaximal rate and then declined and stopped quite in accordance with the phrenicnerve.It is,therefore,reasonable to assume that the central mechanism of theswitch from expiratory apnea to inspiration may originate from this kind ofneurons.Most of the expiratory units show tonic discharges during the period of apneawith a higher discharge rate than normal and then the rate decreases just beforerecovery of phrenic firing.In addition,small portion of the expiratory units weredepressed as the phrenic discharge ceased.The function of these two differentkinds of neurons in the mechanism of development of respiratory rhythm is,apparently,different.