描述一罕见的伴发多种微生物混合感染的眼球痨患者硬性硅酮植入物贯通眼睑移位,经手术去处硅酮、伤口修补和抗生素治疗后病情得以完全缓解。眼球痨患者硬性硅酮植入物贯通眼睑移位@Shah N.J.
@Jalali S.$L. A. Prasad Eye Institute , L. V. Prasad Marg, Banjara Hills, Hyderabad 500 034, India
@Shah V.A.
@Sharma S.
@肖颖 相似文献
梅毒在英国的发病率有上升趋势,尤其在H IV阳性男性中。作者描述1例高加索人,H IV阴性,女性患者,其为二期梅毒,并且具有恶性梅毒特征。患者显示前带现象,快速纤维蛋白溶酶反应素检测为阴性,但是性病实验室检查和梅毒螺旋体血凝集实验结果阳性。恶性梅毒@Watson K.M.T.$Department of Dermatology, King's College Hospital, London SE5 9RS, United Kingdom
@White J.M.L.
@Salisbury J.R.
@Creamer D.
@牛新武… 相似文献
Background: Mitochondrial adenosine triphosphate-sensitive potassium (mitoKATP) channels play a pivotal role in mediating cardiac preconditioning. The effects of intravenous anesthetics on this protective channel have not been investigated so far, but would be of importance with respect to experimental as well as clinical medicine.
Methods: Live cell microscopy was used to visualize and measure autofluorescence of flavoproteins, a direct reporter of mitoKATP channel activity, in response to the direct and highly selective mitoKATP channel opener diazoxide, or to diazoxide following exposure to various anesthetics commonly used in experimental and clinical medicine. A cellular model of ischemia with subsequent hypoosmolar trypan blue staining served to substantiate the effects of the anesthetics on mitoKATP channels with respect to myocyte viability.
Results: Diazoxide-induced mitoKATP channel opening was significantly inhibited by the anesthetics R-ketamine, and the barbiturates thiopental and pentobarbital. Conversely, urethane, 2,2,2-trichloroethanol (main metabolite of [alpha]-chloralose and chloral hydrate), and the opioid fentanyl potentiated the channel-opening effect of diazoxide, which was abrogated by coadministration of chelerythrine, a specific protein kinase C inhibitor. S-ketamine, propofol, xylazine, midazolam, and etomidate did not affect mitoKATP channel activity. The significance of these modulatory effects of the anesthetics on mitoKATP channel activity was substantiated in a cellular model of simulated ischemia, where diazoxide-induced cell protection was mitigated by R-ketamine and the barbiturates, while urethane, 2,2,2-trichloroethanol, and fentanyl potentiated myocyte protection. 相似文献
本文报道1例35岁的男性患者,其单侧小脑损伤,导致同侧上、下肢在同步环形运动时明显的协调障碍,但损伤对侧肢体同步运动或者左右肢体成对运动时,患者并不表现出协调障碍。因此,小脑不仅是联动肢体协调运动的基础,同时也参与调节肢体间的协调运动。小脑偏侧共济失调患者环形运动时的肢体协调缺陷@Bracewell R.M.$Wolfson Ctr. Clin./Cogn. Neurosci., University of Wales, Brigantia Building, Penrallt Road, Bangor,Gwynedd, LL57 2AS, United Kingdom Dr.
@Balasubramaniam R.
@Wing A.M.
@姚庆和… 相似文献
