心脏MR成像评估非心脏病人群的心舒张功能不全:基于性别研究

正目的无症状左心室(LV)舒张功能不全的评估日益受到关注。本研究旨在应用3 T心脏MR(CMR)探讨亚临床型左室舒张功能不全的患病率及不同性别患病率的差异。     

Neurochemical metabolites in the medial prefrontal cortex in bipolar disorder A proton magnetic resonance spectroscopy study

The aim of this study was to investigate proton magnetic resonance spectroscopy metabolite values in the medial prefrontal cortex of individuals with euthymic bipolar disorder. The subjects consisted of 15 patients with euthymic bipolar disorder type Ⅰ and 15 healthy controls. We performed proton magnetic resonance spectroscopy of the bilateral medial prefrontal cortex and measured levels of N-acetyl aspartate, choline and creatine. Levels of these three metabolites in the medial prefrontal cortex were found to be lower in patients with bipolar disorder compared with healthy controls. A positive correlation was found between illness duration and choline levels in the right medial prefrontal cortex. Our study suggests that during the euthymic period, there are abnormalities in cellular energy and membrane phospholipid metabolism in the medial prefrontal cortex, and that this may impair neuronal activity and integrity.     

医院感染现状及应对策略

医院感染（nosocomial infection）一词源于希腊语nosos（疾病）komeion（医疗护理）,意指由医疗护理工作引发的感染病,患者包括在医疗保健机构中接受诊疗的患者、探视者以及医务人员。这种感染在入院时不存在,也不处于潜伏期,而是发生在医院或其他医疗保健机构内。在医院获得而出院后才发病的感染及医疗保健机构工作人员的职业性感染也属于医院感染。医院感染普遍存在,我国估计每年医院感染约为500万例,     

响应面法优化白刺花总黄酮提取工艺研究

目的:优选白刺花中总黄酮的最佳提取工艺。方法:采用响应面分析法优化,以总黄酮提取率为评价指标,在考察单因素试验的基础上,选取乙醇浓度、加液量、提取温度和提取时间为自变量,利用Design-Expert软件分析优化出白刺花中总黄酮的最佳提取工艺条件。结果:优化所得白刺花中总黄酮的最佳提取工艺条件为:乙醇浓度为72%,加液量为21倍,提取温度为71℃,提取时间为133 min。结论:响应面优化所得到的最佳提取工艺准确、稳定,是提取白刺花中总黄酮的可行方法。     

摘要《ANKYLOS~号种植体周围软组织的组织学分析的动物实验研究》

Purpose&Aim:The importance of the soft tissue-implant interface is enhanced by the presence of a micro-gap between the implant and the abutment,which represents a contamination site for bacteria.The aim of this study was to investigate the interface between the ANKYLOS gap-free implant system and the surrounding soft tissues in a dog model.原因与目的:种植体与修复基台的连接处存在着微隙,构成细菌的污染区域,这一特点使得软组织一种植体界面的重要性更加被重视