频率可变的极低频脉冲磁场的生殖效应

初成年雄性ＮＩＨ小鼠、雌性ＮＩＨ小鼠和初孕ＮＩＨ雌鼠分别经３５天、３０天和大部分孕期（１８天）暴露于频率变化的极低频脉冲磁场中，结果发现雄性鼠接触磁场后再与未经接触磁场的健康雌性ＮＩＨ小鼠交配时，其胚胎总死亡率增高，有一个以上死胎的孕鼠率增高。说明磁场能够损伤雄性小鼠的生殖功能     

法莫替丁与H1受体拮抗剂联合治疗慢性荨麻疹124例疗效观察

124例单用H1受体拮抗剂治疗疗效差的慢性荨麻疹患，联合应用法莫替丁治疗4周，结果显示临床痊愈率和显效分别为85．4％和10．5％，表明法莫替丁与H1受体拮抗剂联合用于这类H1受体拮抗剂不能奏效的慢性荨麻疹患是一种有效的治疗方法。     

Differentiation of human epidermal stem cells into fibroblasts induced by TGF-β1 in vitro

Objective To investigate the correlation between human epidermal stem cell (hESCs) and hypertrophic scar or keloid. Methods Improved collagen Ⅳ-coated adhesion methods was used to isolate and culture the epidermal stem cells after neutral protease selectively digested the dermo-epidermal junctions. After the cells were cultured and expanded in vitro, and passage 3 hESCs were induced by different concentrations of TGF-β1 (0.1, 5.0, and 10.0 ng/ml). Morphological fea-tures and identification of these cells were meseasured by HE, Masson, immunohistochemical staining on the days 3 and 7, respectively. Results After induced by TGF-β1 for 3 and 7 days, the morpholo-gy of the epidermal stem cell (hESCs) was changed into fusiform shape, similar to fibroblasts. 70 % ofthe cell which was induced by TGF-β1 were blue stained in the cytoplasm by Masson stain, which is the distinctive method for collagen, suggesting collagen appeared or increased in the cells. The collagen concentrations in supernatants of hESCs were 0.4150±0.0014, 0.3380±0. 0020, and 0.3870±0.0020, much higher than that in control group (0.0780±0.0025) and normal skin fibro-blast group (0.15004±0.0051) (P<0.05). Immunohistochemical staining revealed that positive rates of these cells for anti-vimentin staining were more than (95.00±1.20)% in experiments and (5.70±0.20)% in control group. Conclusion The differentiantion of hESCs induced by TGF-β1 into fibro-blasts indicates that hESCs may play a role in the pathogenesis of hypetrophic scar and keloid.     

以高钙性肾病为突出表现的原发性甲状旁腺功能亢进1例

以高钙性肾病为突出表现的原发性甲状旁腺功能亢进１例大连医科大学附属第二医院肾内科（１１６０２３）尹永红麻军患者男，４２岁。以多饮、多尿２年，恶心、呕吐３个月为主诉入院。２年前出现烦渴、多饮，每日饮水量７５００～１００００ｍｌ，多尿、夜尿增多。未介意。...     

乙型肝炎与肝癌关系的流行病学研究—广西HBsAg携带者及肝损害者的分布及发生肝癌的前瞻性研究

本文对20岁以上22830人按HBsAg状况和肝损害表现分队列进行随访,平均追踪6.8年,在肝癌高发区和低发区均以HBsAg携带者并有重度肝损害者(肝大+肝功能异常)的肝癌死亡率和相对危险性最高,相对危险性分别为37.3和22.5倍。以无肝大和肝功能异常的非携带者最低,肝癌的发生和肝损害的程度呈平行关系。HBsAg携带者发生肝癌死亡的相对危险性高于非携带者7倍,并发现HBsAg携带并有重度肝损害的肝癌死亡的平均年龄显著提前。认为肝癌高发区人群中HBV的持续感染和肝损害的广泛存在是导致肝癌高发和早发的重要因素。     

松节油合成的杀虫增效剂

杀虫增效剂是指对昆虫没有或者很少有杀虫效果的一类化学品,但当它与某些杀虫剂混合使用,能提高杀虫剂的药效,从而达到减少杀虫剂用量,降低成本,减少环境污染的目的。同时,随着长时间的用药,许多害虫对一些杀虫剂均有不同程度的抗性,加入增效剂也是减少抗性的手段之一。 松节油是松脂加工后得到的萜烯类物质,     

“妙方”治疗糖尿病

糖尿病患者要想获得满意的治疗效果,必须三种疗法综合施用。这三种疗法就是:①控 制饮食②长期定量运动③服用降血糖药物或皮下注射胰岛素。其中饮食控制是治疗的基础。没有定量进食,单用任何降血糖药物(包括胰岛素注射〕都不会得到对高血糖的满意控制。这是因为糖尿病人体内没有胰岛素,或是周围组织对胰岛素有抵抗性使之不能充分发挥生物效应,所以病人自身体内没有或很少有降血糖的激素效应。当精神激动、发烧、外伤、失眠等应激引起的肝糖原分解血糖升高时,正常人自动地立即按需分泌出足够的胰     

浅谈气管切开术后气道湿化的护理

我们从1987年10月至1993年6月,共为86例做气管切开术后的患者实施了气道湿化、护理、其中11例患者终因病情危重而死亡,其它患者湿化效果均较好。现谈谈我们的体会。