全程助产责任制与产科质量

目的分析大型医院导乐陪伴分娩模式中全程助产责任制与产科质量的关系.方法把2003年3 671例及1997年3 789例全年随机到保健院产房分娩的产妇分为两组进行对照,一组为全程助产责任制下的导乐陪伴分娩组,另一组为传统产房模式组.结果导乐陪伴分娩组难产率明显低于对照组,第一产程和第二产程明显短于对照组;产时产后2 h内出血量明显少于对照组,新生儿窒息发生率明显低于对照组;两组自然分娩率和剖宫产率相似,无显著差异.结论产程助产责任制度在产妇数量较大的医院实施导乐陪伴分娩中是一种有效的模式,可提高产科质量,保证母婴安全.     

构建医院协会"四位一体"创新模式

介绍了广东省医院协会构建“四位一体”的组织创新模式:医院协会、广东现代医院管理研究所、广东《现代医院》杂志社、广东现代医院管理顾问有限公司的形成、发展成为协会做强做大的载体和基础的体会。     

螺旋CT机图像传输系统与其外设网络传输线路的改建

通过改建图像传输网络线路,使图像传输系统传输CT图像更加方便、稳定、快捷.     

多种工作模式的踝关节活动器的研制

各种原因导致患者长期卧床后将引起严重的并发症:踝关节跖屈畸形。新型踝关节活动器以大扭矩、超低速电机为动力,结合定时控制电路,具有多种工作模式,能使踝关节在被动的情况下背伸20～30°,跖屈40～50°,并能根据患者的个体情况设置不同的运用角度与时间,且能根据需要进行缓慢、连续、往返式运动,这对那些踝关节不能或较难进行主动活动的病人防止踝关节跖屈畸形、踝关节僵硬的及下肢肌肉萎缩有良好的作用。     

BDNF is involved in sympathetic sprouting in the dorsal root ganglia following peripheral nerve injury in rats

Peripheral nerve injury results in sympathetic sprouting around large diameter sensory neurons in the dorsal root ganglia (DRG). The mechanism underlying this pathological phenomenon is not known. Brain-derived neurotrophic factor (BDNF) is up-regulated in large sensory neurons and ensheathing satellite cells following a sciatic nerve injury. In the present study, we investigated the effects of BDNF on the sympathetic sprouting in the DRG, by delivering BDNF antibody or antisense oligodeoxynucleotide to injured DRGs, or by delivering exogenous BDNF to intact DRGs. The sheep antibody to BDNF, characterized by bioassays and dot blots, specifically reacted with BDNF but not other neurotrophins. Noradrenergic fibers were visualized by immunostaining of tyrosine hydroxylase (TH) and quantified by an NIH Imaging program. Two weeks following L5 spinal nerve lesion, a dramatic increase in TH-immunoreactive (-ir) fibres was observed in both ipsi- and contralateral DRGs in normal sheep IgG treated rats. BDNF antibody significantly reduced the sprouting of sympathetic nerves in both ipsi- and contra-lateral DRGs by 67% and 42% respectively. BDNF antisense oligodeoxynucleotide, by inhibiting BDNF synthesis in DRGs, also significantly suppressed the sprouting by 67% and 60% respectively in the ipsi- and contra-lateral DRGs. Delivery of exogenous BDNF into an intact L5 DRGs resulted in an increase in the sprouting by 4.2-fold. Our results clearly indicate that BDNF, synthesized in and secreted from the DRGs, is involved in the sympathetic sprouting in the DRG following the peripheral nerve injury.     

金莲花软胶囊中总黄酮的含量测定

目的建立紫外法测定金莲花软胶囊中总黄酮的含量测定方法。方法采用紫外分光光度计,检测波长500nm,以芦丁为标准品测定本品总黄酮含量。结果测得线性回归方程为y=0.11359x-0.0034,r=0.9999(n=5),平均回收率为99.67%,RSD为0.58%(n=9)。结论本方法简便,准确、重复性好。     

At the heart of the problem: congestive cardiac failure as a cause of ascites: A narrative review

Heart failure leading to cardiac ascites is an extremely rare and underrecognized entity in clinical practice. Recognizing cardiac ascites can be difficult, especially since patients presenting with ascites may have more than 1 etiology. Various biomarkers are available to aid in the diagnosis of cardiac ascites, though with differing sensitivities and specificities. Such biomarkers include serum albumin, ascitic albumin and protein, as well as serum N-terminal pro-brain natriuretic peptide (NT-proBNP). While serum NT-proBNP is a powerful biomarker in distinguishing the etiology of ascites and monitoring treatment progression, its cost can be prohibitive in low-resource settings. Clinicians practicing under these circumstances may opt to rely on other parameters to manage their patients. We go on further to report a series of 3 patients with cardiac ascites to illustrate how these biomarkers may be employed in the management of this patient population. Clinicians should always keep in mind the differential diagnosis of cardiac failure as a cause of ascites. The resolution of cardiac ascites may serve as a surrogate clinical marker for response to antifailure therapy in lieu of NT-proBNP at resource-scarce centers.     

复杂坠落伤28例诊断与治疗体会

坠落伤多为复合伤,患者入院时多有不同程度的休克和昏迷,伤情复杂,患者病史叙述不清,查体难以合作,诊治不当易造成死亡。我院2002年1月~2004年12月收治坠落伤28例,重度多发伤比例高,我们严格按照Crashplan或VIPCO程序进行,遵循边抢救边诊断的原则,治愈20例、好转6例,取得满意疗     

慢性肺源性心脏病急性加重期98例糖代谢异常分析

目的:探讨慢性肺源性心脏病(肺心病)急性加重期糖代谢异常变化及其原因。方法:选择无糖尿病病史的肺心病急性加重期患者98例进行糖耐量试验(OGTT),并同健康对照组相比较。结果:肺心病患者血糖峰值为(8.46±0.61)mmol/L,显著高于对照组(7.59±0.50)mmol/L(P<0.01);平均高峰时间为(0.60±0.18)小时,而对照组为(0.75±0.24)小时,2组差异有显著性意义(P<0.05)。结论:肺心病患者糖代谢异常,可能与胰岛素分泌不足和胰岛素灭活障碍有关。     

A First-Principles Study on the Hydration Behavior of (MgO)n Clusters and the Effect Mechanism of Anti-Hydration Agents

Magnesia-based refractory is widely used in high-temperature industries; its easy hydration is, however, a key concern in refractory processing. Understanding the hydration mechanism of MgO will help in solving its hydration problem. Herein, the hydration behavior of (MgO)_n (n = 1–6) at the molecular level and the effect mechanisms of several anti-hydration agents on the hydration of (MgO)₄ were investigated with first-principles calculations. The results indicated that the following: (1) The smaller the (MgO)_n cluster size, the more favorable the hydration of MgO and the tendency to convert into Mg(OH)₂ crystal; (2) Anti-hydration agents can coordinate with the unsaturated Mg atom of (MgO)₄ to form a bond, increasing the coordination number of Mg, thus reducing its activity when reacting with H₂O; (3) The greater the number of −COOH groups and the longer the chain length in the anti-hydration agents, the better its effect of inhibiting the hydration of MgO. These findings could enhance the understanding of the mechanism of hydration of MgO and provide theoretical guidance for the design of novel anti-hydration agents.