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991.
992.
目的定量描述口部运动时,与其相关联的面部标记点运动,以探索评价面瘫、面肌联带运动的三维定量新方法。方法健康志愿者22人(45-60岁),利用"基于运动捕捉的面肌运动三维动态分析系统",采集"用力示齿"、"向右上拉口角"、"向左上拉口角"、"微笑"四个表情动作时,面部相关联标记点(眉弓点、上下眼睑点、内眦点、外眦点)的运动,以最大移动距离(Smax)和最大速率(Vmax)两个参数描述。结果 1.口周运动为主的表情动作中,面部其他部位标记点均有运动,且与位于口周的标记点在某一表情运动中其达到Smax或Vmax的时间分别是一致的。2."用力示齿"动作:Smax下眼睑点(左3.93mm,右4.15mm)>外眦点>上眼睑点>眉弓点>内眦点(左1.59mm,右1.53mm);Vmax眼睑点左上(42.643mm/s)>余眼睑标记点(31.58mm/s-37.62mm/s)>外眦点>眉弓点>内眦点(左11.71mm/s,右11.09mm/s)。3."微笑"动作:Smax及Vmax上眼睑点(左3.05mm,36.14mm/s;右2.53mm,28.90mm/s)>下眼睑点>外眦点>眉弓点>内眦点(左0.69mm,7.22mm/s;右0.77mm,7.80mm/s)。4."向右上拉口角"动作,Smax及Vmax外眦点及下眼睑点右侧明显大于左侧,内眦点右侧略大于左侧,上眼睑点、眉弓点左侧略大于右侧。5."向左上拉口角"Smax及Vmax外眦点、上眼睑点、下眼睑点左侧明显大于右侧,余标记点左侧略大于右侧。结论健康人进行口部运动时,会引起面部其他部位标记点发生相关联的运动,其达到Smax或Vmax的时间分别是一致的。在同一表情动作中,上、下眼睑点及外眦点的Smax、Vmax大于内眦点、眉弓点。Smax及Vmax的较小值出现于"微笑"动作内眦点;较大值出现于"用力示齿"动作下眼睑点。"向左上拉口角"动作同侧面部标记点Smax及Vmax均大于对侧相对称部位标记点。表情动作时面部无静止点。 相似文献
993.
Comparative study of CD4 and CD45RO T cells and CD20 B cells in cerebrospinal fluid of syphilitic meningitis and tuberculous meningitis patients
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Nian Yu Qiao‐quan Zhang Kang Zhang Yuan Xie Hai‐qing Zhu Xing‐jian Lin Qing Di 《APMIS : acta pathologica, microbiologica, et immunologica Scandinavica》2016,124(9):764-769
This study was to investigate the differences of lymphocyte in the cerebrospinal fluid (CSF) of patients with syphilis meningitis (SM) and tuberculous meningitis (TBM) for new diagnostic insights. Totally, 79 cases of SM and 45 cases of TBM were enrolled. In the CSF, the CD4, CD45RO or CD20 positive lymphocytes were detected by immunohistochemistry. The proportion of CD4 T cells in the CSF lymphocytes in patients with SM was significantly higher than that in patients with TBM (p < 0.05). After medical therapy, there was a significantly decline trend of the CD4 T‐cell proportion in both groups (p < 0.05). The proportion of CD45RO T cells in CSF lymphocytes of patients with SM was less than that of patients with TBM (p < 0.05). After medical therapy, the positive ratio of CD45RO T cells was increased in the CSF of both group patients (p < 0.05). The proportion of CD20B cells in the CSF lymphocytes was not obviously different between the two groups during every stage. In conclusion, there are strong differences of CD4 and CD45RO T‐cell ratio, but not the CD20 B cells in the meningitis. CD4 and CD45RO T cells in CSF are a useful complement in differentially diagnosing SM and TBM; it contributes to further understand the pathogenesis and prognosis of SM and TBM. 相似文献
994.
In this review, some important clinical advances presented at the 2011 American Society of Clinical Oncology (ASCO) meeting
are summarized. Emerging trends in clinical oncology research are also discussed based on an analysis of the ASCO abstract
database in recent years. 相似文献
995.
996.
目的:通过对一组肝脏包虫囊肿和非寄生虫性囊肿进行弥散成像以及囊液的生化值的分析,帮助鉴别仅凭单纯影像和血清学试验无法作出肯定诊断的包虫囊肿,并进一步分析研究包虫囊肿和非寄生虫性囊肿囊液的代谢物、电解质、葡萄糖和蛋白质浓度存在差异。资料和方法:通过对29例肝脏囊型包虫病患者以及17例肝脏单纯性囊肿患者进行弥散成像,取其中20例肝脏囊性病灶囊液(其中包虫囊肿13例,非寄生虫性囊肿7例)进行电解质、葡萄糖和蛋白质浓度生化测定。结果:肝脏包虫囊肿在b值1 000 mm/s2弥散图像上ADC值低于肝脏单纯性囊肿,差异有统计学意义,13例肝脏包虫囊肿囊液中葡萄糖、钙离子浓度高于非寄生虫性囊肿,两者间差异有统计学意义。结论:通过肝脏弥散成像可以帮助鉴别包虫囊肿和单纯性囊肿,尤其是早期包虫囊肿,包虫囊肿囊液的葡萄糖含量高于单纯性囊肿,而蛋白含量两者无统计学差异,推测葡萄糖作为大分子物质吸附水分子而导致水分子弥散受限。 相似文献
997.
目的 评价Peplau人际关系理论对于提高护士沟通能力的影响.方法 对宁波市某三甲医院共50名护士进行了8次的Peplau人际关系理论训练,对训练前后护士的临床沟通能力进行比较.结果 训练后护士的临床沟通能力明显高于训练前,差异有统计学意义.结论 Peplau人际关系理论训练能够有效提升护士的临床沟通能力. 相似文献
998.
Qingying Luo Yanhao Lai Shukun Liu Mei Wu Yuan Liu Zunzhen Zhang 《Environmental and molecular mutagenesis》2012,53(5):325-333
Deregulated expression of DNA polymerase beta (pol β) has been implicated in genomic instability that leads to tumorigenesis, yet the mechanisms underlying the pol β‐mediated genetic instability remain elusive. In this study, we investigated the roles of deregulated expression of pol β in spontaneous and xenobiotic‐induced genetic instability using mouse embryonic fibroblasts (MEFs) that express distinct pol β levels (wild‐type, null, and overexpression) as a model system. Three genetic instability endpoints, DNA strand breaks, chromosome breakage, and gene mutation, were examined under various expression levels of pol β by comet assay, micronuclei test, and hprt mutation assay. Our results demonstrate that neither pol β deficiency nor pol β overexpression is sufficient for accumulation of spontaneous DNA damage that promotes a hyperproliferation phenotype. However, pol β null cells exhibit increased sensitivity to exogenous DNA damaging agents with increased genomic instability compared with pol β wild‐type and overexpression cells. This finding suggests that a pol β deficiency may underlie genomic instability induced by exogenous DNA damaging agents. Interestingly, pol β overexpression cells exhibit less chromosomal or DNA damage, but display a higher hprt mutation frequency upon methyl methanesulfonate exposure compared with the other two cell types. Our results therefore indicate that an excessive amount of pol β may promote genomic instability, presumably through an error‐prone repair response, although it enhances overall BER capacity for induced DNA damage. Environ. Mol. Mutagen. 2012. © 2012Wiley Periodicals, Inc. 相似文献
999.
Jia-Ling Song Yao Yuan Hai-Bo Tan Ri-Ming Huang Hong-Xin Liu Zhi-Fang Xu 《Journal of Asian natural products research》2017,19(3):222-228
Two new coumarins, named (±)-euryacoumarin A (1) and 6-demethylobtusinin (2), and one new natural coumarin, named euryacoumarin B (3), along with two known compounds, scopoletin (4) and obtusinol (5), were isolated from the stems of Eurya chinensis. Their structures were elucidated by means of extensive spectroscopic methods and comparison with data reported in the literatures. Compound 1 exhibited significant inhibition of LPS-induced nitric oxide (NO) production in RAW264.7 cells with IC50 value of 35.64 ± 1.73 μM, and showed marginal antibacterial activities against Bacillus subtilis and B. cereus with MIC values of 50.59 ± 2.12 and 35.42 ± 0.96 μM, respectively. 相似文献
1000.