古尼拟青霉对小鼠缺血性脑损伤保护作用研究

探讨古尼拟青霉对小鼠急性脑损伤的保护作用。发现古尼拟青霉能显著延长小鼠断头后张口呼吸持续的时间,使小鼠双侧颈总动脉（含迷走神经）不完全结扎后的存活时间明显延长,提示该药可能对缺血性脑损伤有一定的保护作用。     

五灵胶囊治疗慢性肝炎的临床随访观察

0　引言　五灵丸治疗慢性病毒性肝炎取得了较好的疗效 [1 ] ,但五灵丸为大蜜丸 ,不易被患者所接受 ,且其消化道副作用较明显 .为此 ,我们改进剂型 ,研制成五灵胶囊 ,为明确其能否保持远期疗效 ,我们对用该药治疗的患者进行随访观察 ,同时与五灵丸的疗效进行比较 .1　对象和方法1.1　病例选择　按慢性肝炎的诊断标准选择住院患者 10 0例 ,随机分为两组 .治疗组为五灵胶囊组 ,对照组为五灵丸组 .每组各 5 0例 .治疗组轻度 19例 ,中度 2 0例 ,重度 11例 .对照组轻度 2 0例 ,中度 18例 ,重度 12例 .两组均选择 18～5 8岁 ,病程 1～ 2 0 a.平均 4…     

综合疗法治愈狼疮性急性肾衰1例

1　病例报告　患者 ,女 ,6 0岁 ,因反复发热 2 5 a、全身性关节疼痛 2 3 a,双下肢水肿 2 mo,腹胀、尿少 1mo,于 1998- 10 - 2 0入院 .1975年患者出现发热 ,全身关节疼痛 ,四肢关节周围皮肤出现结节性红斑 ,触之疼痛 ,多次化验血沉 115 mm· h- 1 ,抗核抗体阴性 ,类风湿因子阳性 ,未找到狼疮细胞 ,诊断为“类风湿性关节炎”.1986年因上述症状复发再次入我院 ,多次检查后发现血抗核抗体 ( ) ,抗双链 DNA抗体 ( ) ,临床确诊为系统性红斑狼疮 (SL E) ,狼疮性肝炎 ,狼疮性胸膜炎 ,狼疮性肺炎 .经治疗好转 ,但上述症状反复发作 .此次上述症状复…     

药疹132例临床分析

目的 :探讨药疹与某些致敏药物的联系。方法 :查阅了 1998年 1月～ 1999年 12月我院药疹病历 132例 ,对致敏药物的种类及疹型进行了统计分析。结果 :怀疑致敏药物 6 5种 ,药疹的分型以荨麻疹型最多 ,其次为麻疹样型和猩红热型。结论 :引发药疹最多的药物是抗菌药物 ,其次是解热镇痛药和中药     

甲状腺激素在慢性肾功能不全患者血清中的变化

目的 :为研究慢性肾功能不全 (CRF)时甲状腺激素的变化及其临床意义。方法 :应用放射免疫法 (RIA)检测 47例CRF患者 ,2 1例肾功能正常的肾脏疾病患者和 2 4例正常人 T3、T4、FT3、FT4、TSH。结果 :CRF患者血清 T3、T4、FT3、FT4明显降低 (P<0 .0 5 ,P<0 .0 1) ,并与 Scr呈显著负相关 (P<0 .0 5 ,P<0 .0 1)。结论 :CRF病例存在继发性甲状腺功能减退症 ,甲状腺激素可作为判定肾功能受损程度的参考指标。     

COMPLICATIONS IN LAPAROSCOPIC GYNECOLOGIC SURGERY

Objective. To investigate retrospectively the complications and associated factors of gynecological laparescopies.Methods. 1769 laparoscopic surgeries were carried out from January 1994 to October 1999 at our department. The procedures included 1421 surgeries of ovary and tube, 52 myomectomies and 296 cases of laproscopic-assisted vaginal hysterectomy (LAVH). A total of 312 patients had a history of prior laparotomy (17.6%). Results. Complications occured in 34 cases, the overall complication rate was 1.92%. Unintended laparotomies occured in 6 cases(0.34% ). 12 complications were associated with insertion of Veress needle or trocar and creation of pneumoperitoneum, including 5 severe emphysema and 7 vascular injuries, this figure represents 35.3% of all complications of this series. Five intraopemtive complications (14.7 % ) occured during the laparescopic surgery (3 severe bleedings, one bladder injury and one skin bum of leg caused by damaged electrode plate), laparotomy was re-quired in four of these cases. Seventeen complications occured during postoperative stage: 2 intraperitoneal hemor-rhages needing laparotomy, 2 bowel injuries, 4 nerve paresis and 9 febrile morbidities. Cordusions. Operative gynecologic laparoscopy is associated with acceptable morbidity rate, but can not be over-looked. Complication rate seems to be higher in advanced procedures such as LAVH.     

STUDY ON MODIFIED COLD STORAGE METHOD OF RAT LIVERS WITH SELF-MADE HYD SOLUTION

ＩＮＴＲＯＤＵＣＴＩＯＮ　　Ｔｈｅｍｅｔｈｏｄｏｆｃｏｌｄｌｉｖｅｒｐｒｅｓｅｒｖａｔｉｏｎｉｓａｃｒｕｃｉａｌｌｉｍｉｔ ｉｎｇｆａｃｔｏｒｉｎｔｈｅｄｕｒａｔｉｏｎｏｆｌｉｖｅｒｐｒｅｓｅｒｖａｔｉｏｎ .Ｅｘｐｅｒｉｍｅｎｔａｌｅｖｉｄｅｎｃｅｈａｓｓｈｏｗｎｔｈａｔｎｏｎｐａｒｅｎｃｈｙｍａｌｃｅｌｌｓａｒｅｍｏｒｅｖｕｌｎｅｒａｂｌｅｔｏｈｙｐｏｔｈｅｒｍｉｃｓｔｏｒａｇｅｔｈａｎｈｅｐａｔｏｃｙｔｅ,ｉｎｄｉｃａｔｉｎｇｔｈａｔｐｒｏｔｅｃｔｉｏｎｏｆｔｈｅｍｉｃｒｏｖａｓｃｕｌａｔｕｒ…     

严重烧伤病人早期肾功能损害与早期糖尿症的相关性研究

目的 :通过对严重烧伤病人进行应激性糖尿症和早期肾功能损害等并发症观察研究 ,进一步了解其发病机制。方法 :对重度烧伤病人进行血 BS、BUN、Cr、UA、TNFα、INS、β2 - MG及尿糖、尿 PRO、尿 p H、尿β2 - MG等进行监测。结果 :发现 5例病人在血糖不高的情况下出现糖尿和不同程度的肾功能损害。结论 :部分严重烧伤病人早期糖尿是由肾脏近曲小管吸收障碍引起。     

重型胆源性胰腺炎术后死亡原因分析

目的：分析重型胆源性胰腺炎的死亡原因,方法：对我院自１９８８年４月至１９９８年１２月间行早期手术的重型胆源性胰腺炎６３例,术后死亡２６例作回顾性分析,结果：术后３ｄ内死亡１２例,其余术后２４ｄ死亡,死亡主要原因为休克、ＡＲＤＳ等。结论早期手术仍有较高的病死亡率。     

Simultaneous Construct Surface Microstructural and Internal Network-Like Conductive Pathways of Poly(l-lactic acid)/Carbon Nanomaterials Composite Foams

The poly(l -lactic acid) (PLLA)/carbon nanomaterials composite foams with hierarchical surface microstructural and internal conductive pathways are successfully prepared by a simple crystallization-assisted rapid phase separation (CARPS). The dimension and morphology of carbon nanomaterials can induce different crystallization forms to construct the hierarchical surface microstructure, and they are distributed on the phase interface of solvent and non-solvent to form conductive pathways. It is found that the heterogeneous nucleation of nanomaterials promotes a significant increase in crystallinity, and a stacked granular structure formed on the surface promotes the increase of the water contact angle to 148.7°. Foams with interconnecting pore structures contribute to the formation of 85.3% porosity and 12.33 g g⁻¹ oil absorption. Carbon nanomaterials are distributed on the pore walls of the porous foam, which converts the foam from an insulating material to a conducting polymer. Furthermore, the uniform distribution of nanomaterials significantly affects the thermal stability of the PLLA. In belief, the multifunctional biodegradable foam, prepared by a CARPS method, makes it promising for industrial production and has potential applications in electrical conductivity, oil-water separation, and many other fields.