全文获取类型
收费全文 | 8232篇 |
免费 | 555篇 |
国内免费 | 178篇 |
专业分类
耳鼻咽喉 | 165篇 |
儿科学 | 94篇 |
妇产科学 | 115篇 |
基础医学 | 1405篇 |
口腔科学 | 108篇 |
临床医学 | 606篇 |
内科学 | 1914篇 |
皮肤病学 | 258篇 |
神经病学 | 616篇 |
特种医学 | 533篇 |
外科学 | 1059篇 |
综合类 | 35篇 |
一般理论 | 2篇 |
预防医学 | 253篇 |
眼科学 | 327篇 |
药学 | 704篇 |
中国医学 | 91篇 |
肿瘤学 | 680篇 |
出版年
2024年 | 3篇 |
2023年 | 61篇 |
2022年 | 224篇 |
2021年 | 336篇 |
2020年 | 149篇 |
2019年 | 231篇 |
2018年 | 314篇 |
2017年 | 209篇 |
2016年 | 414篇 |
2015年 | 499篇 |
2014年 | 517篇 |
2013年 | 620篇 |
2012年 | 882篇 |
2011年 | 831篇 |
2010年 | 480篇 |
2009年 | 403篇 |
2008年 | 499篇 |
2007年 | 484篇 |
2006年 | 365篇 |
2005年 | 363篇 |
2004年 | 285篇 |
2003年 | 221篇 |
2002年 | 183篇 |
2001年 | 86篇 |
2000年 | 74篇 |
1999年 | 53篇 |
1998年 | 31篇 |
1997年 | 15篇 |
1996年 | 9篇 |
1995年 | 14篇 |
1994年 | 8篇 |
1993年 | 10篇 |
1992年 | 12篇 |
1991年 | 9篇 |
1990年 | 9篇 |
1989年 | 15篇 |
1988年 | 4篇 |
1987年 | 10篇 |
1986年 | 5篇 |
1985年 | 3篇 |
1984年 | 2篇 |
1983年 | 2篇 |
1982年 | 1篇 |
1979年 | 6篇 |
1978年 | 1篇 |
1977年 | 3篇 |
1976年 | 4篇 |
1975年 | 4篇 |
1973年 | 1篇 |
1967年 | 1篇 |
排序方式: 共有8965条查询结果,搜索用时 15 毫秒
91.
The aim of the present study was to investigate the impact of perceived stress and self‐esteem on work‐related stress and depression. Two hundred and eighty‐four Korean nurses participated in the study. The participants completed four questionnaires, including the Korean short version of the occupational stress scale, the perceived stress scale, the Rosenberg self‐esteem scale and the Beck depression inventory. Structural equation modelling was used to determine the relationships among work‐related stress, perceived stress, self‐esteem, and depression. Work‐related stress was positively associated with depression. Perceived stress was inversely related to self‐esteem and positively associated with work‐related stress and depression, respectively. Self‐esteem was negatively associated with work‐related stress and depression. Structural equation modelling revealed that self‐esteem and perceived stress fully mediate the relationship between work‐related stress and depression. Future studies should further investigate the effect of psychological characteristics on work‐related stress and symptoms of depression. Copyright © 2012 John Wiley & Sons, Ltd. 相似文献
92.
93.
Tai Kyung Noh Seok Joo Choi Bo Young Chung Jin Soo Kang Jong Hee Lee Mi Woo Lee Sung Eun Chang 《The Journal of dermatology》2014,41(9):788-794
Melasma is triggered by various factors including ultraviolet radiation and estrogen; however, its pathogenesis is unclear. To investigate the inflammatory features of melasma lesions as triggers for this disorder, 197 women with melasma who attended Asan Medical Center and Kangskin Clinic, Seoul, from June 2011 to October 2011 completed a questionnaire concerning triggering or aggravating factors. These cases were divided into “non‐inflammatory” and “inflammatory” groups. Skin biopsies and immunostaining for CD68, CD117, and leukocyte common antigen (LCA) were performed in the lesional and peri‐lesional skin of ten cases in the non‐inflammatory group and nine cases in the inflammatory group. Among the 197 subjects (mean age, 41.5 years; mean age of melasma onset, 33.8 years), 50 patients (25.4%) were categorized into the inflammatory group. This group comprised cases that had inflammatory symptoms and events that triggered the melasma lesions. The lesional dermis contained more CD68+ melanophages, CD117+ mast cells, and LCA+ leukocytes in the inflammatory group than in the non‐inflammatory group. Inflammatory clinical features and an increased number of inflammatory cells in the lesion may be involved in the development of melasma in Asian skin. 相似文献
94.
Mi Young Jung Jae Hyoung Lee Cho Rok Kim Hyun Je Kim Won Jung Koh Chang Suk Ki Joo Heung Lee Jun Mo Yang Dong Youn Lee 《ANNALS OF DERMATOLOGY》2014,26(1):92-95
Mycobacterium massiliense which is recognized as a separate species from M. abscessus is little known regarding its clinical patterns and the response to treatment. We present a case of a localized cutaneous infection due to M. massiliense of the sole associated with acupuncture. M. massiliense was identified via polymerase chain reaction-hybridization analysis. We treated the patient with single-drug therapy consisting of clarithromycin for 4 months and the patient showed a significant response to this treatment. 相似文献
95.
Cynthia X. L. Chang Anthony T. Tan Ming Yan Or Kai Yee Toh Pei Yiing Lim Adeline S. E. Chia Thomas M. Froesig Karen D. Nadua Hsueh‐Ling J. Oh Hoe Nam Leong Sine R. Hadrup Adam J. Gehring Yee‐Joo Tan Antonio Bertoletti Gijsbert M. Grotenbreg 《European journal of immunology》2013,43(4):1109-1120
Conditional ligands have enabled the high‐throughput production of human leukocyte antigen (HLA) libraries that present defined peptides. Immunomonitoring platforms typically concentrate on restriction elements associated with European ancestry, and such tools are scarce for Asian HLA variants. We report 30 novel irradiation‐sensitive ligands, specifically targeting South East Asian populations, which provide 93, 63, and 79% coverage for HLA‐A, ‐B, and ‐C, respectively. Unique ligands for all 16 HLA types were constructed to provide the desired soluble HLA product in sufficient yield. Peptide exchange was accomplished for all variants as demonstrated by an ELISA‐based MHC stability assay. HLA tetramers with redirected specificity could detect antigen‐specific CD8+ T‐cell responses against human cytomegalovirus, hepatitis B (HBV), dengue virus (DENV), and Epstein‐Barr virus (EBV) infections. The potential of this population‐centric HLA library was demonstrated with the characterization of seven novel T‐cell epitopes from severe acute respiratory syndrome coronavirus, HBV, and DENV. Posthoc analysis revealed that the majority of responses would be more readily identified by our unbiased discovery approach than through the application of state‐of‐the‐art epitope prediction. This flow cytometry‐based technology therefore holds considerable promise for monitoring clinically relevant antigen‐specific T‐cell responses in populations of distinct ethnicity. 相似文献
96.
Chang Kyu Park Dong Chan Lee Chan Joo Park Jang Hoe Hwang 《Journal of Korean Neurosurgical Society》2013,54(5):423-425
We present a case report to remind surgeons of this unusual complication that can occur in any surgery, even posterior cervical spine surgery under general anesthesia and discuss its causes, treatment methods, and the follow-up results in the literature. The peripheral Tapia''s syndrome is a rare complication of anesthetic airway management. Main symptoms are hoarseness of voice and difficulty of tongue movement. Tapia''s syndrome after endotracheal general anesthesia is believed to be due to pressure neuropathy of the vagus nerve and the hypoglossal nerve caused by the endotracheal tube. To our knowledge, no report has been published or given an explanation for Tapia''s syndrome after posterior cervical spine surgery. Two patients who underwent posterior cervical surgery complained hoarseness and tongue palsy postoperatively. There is no direct anatomical relation between the operation, the vagus nerves and the hypoglossal nerves, and there is no record of displacement or malposition of the endotracheal tube. After several months, all symptoms are resolved. To avoid this problem in posterior cervical spine surgery, we suggest paying special attention to the position of the endotracheal tube to avoid excessive neck flexion before and during the positioning of the patient. 相似文献
97.
Urine clusterin/apolipoprotein J is linked to tubular damage and renal outcomes in patients with type 2 diabetes mellitus 下载免费PDF全文
98.
Changsun Kim Bo Seung Kang Hyuk Joong Choi Young Joo Lee Gu Hyun Kang Wook Jin Choi In Ho Kwon 《J Am Med Inform Assoc》2014,21(1):17-22
To examine the use of online social networking for cardiovascular care using Facebook. All posts and comments in a Facebook group between June 2011 and May 2012 were reviewed, and a survey was conducted. A total of 298 members participated. Of the 277 wall posts, 26.7% were question posts requesting rapid replies, and 50.5% were interesting cases shared with other members. The median response time for the question posts was 16 min (IQR 8–47), which tended to decrease as more members joined the group. Many members (37.4%) accessed the group more than once a day, and more than half (64%) monitored the group posts in real time with automatic notifications of new posts. Most members expressed confidence in the content posted. Facebook enables online social networking between physicians in near-real time and appears to be a useful tool for physicians to share clinical experience and request assistance in decision-making. 相似文献
99.
100.
Kyung Kgi Park Young Joo Kim Sung Dae Kim Jung Sik Huh 《Neurourology and urodynamics》2014,33(4):469-470